Publications
2022
- Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection. Matthew Bowler, Marta Glavatskikh, Chad V. Pecot, Dmitri Kireev, Albert Bowers. American Chemical Society Chemical Biology (Accepted ahead of Press), 2022. 8 pages. PMID: 36490372
- Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer. Ryan M. Murphy, Jason Tasoulas, Alessandro Porello, Miranda B. Carper, Yi-Hsuan Tsai, AlishaCoffey, Sunil Kumar, Bentley R. Midkiff, Stephanie Cohen, Ashley Salazar, Michele Hayward, DavidN. Hayes, Andrew Olshan, Gaorav P. Gupta, Wendell Yarbrough, Chad V. Pecot, Antonio L. Amelio. Cancer Research Communications (Accepted ahead of Press), 2022. 8 pages. PMID: 36148399
- Targeting Brain Lesions of Non-Small Cell Lung Cancer by Enhancing CCL2-Mediated CAR-T Cell Migration. Hongxia Li, Emily Harrison, Huizhong Li, Koichi Hirabayashi, Jing Chen,Qi-xiang Li, Jared Gunn, Jared Weiss, Barbara Savoldo, Joel Parker, Chad V. Pecot, Gianpietro Dotti, and Hongwei Du. Nature Communications, 2022. 8 pages. PMID: 35443752
- Rapid Idiosyncratic Mechanisms of Clinical Resistance to KRAS G12C Inhibition. Yihsuan S. Tsai, Mark G. Woodcock, Salma H. Azam, Leigh B. Thorne, Joel S. Parker, Benjamin G.Vincent, Chad V. Pecot. Journal of Clinical Investigation, 2022. 8 pages.PMID: 34990404 #Corresponding Author (*Journal Cover)
- Cancer Discovery Commentary, “Multiple Mechanisms Underlie the Acquired Resistance to KRAS G12C Inhibition
- Journal of Clinical Investigation Commentary, “Remodeling of the tumor/tumor microenvironment ecosystem during KRAS G12C inhibitor clinical resistance in lung cancer”
2021
- Targeting Disialoganglioside GD2 with Chimeric Antigen Receptor-Redirected T cells in Lung Cancer. Loïc Reppel, Ourania Tsahouridis, Jason Akulian, Ian Davis, Giovanni Fucá, Lee Hong, Jared Weiss, Gianpietro Dotti, Chad V. Pecot, and Barbara Savoldo. Journal for ImmunoTherapy in Cancer, 2021. 8 pages. PMID: 35022195
- Consolidation with pembrolizumab and nab-paclitaxel after induction platinum-based chemotherapy for advanced non-small cell lung cancer (NSCLC). Shetal A. Patel, David E Gerber, Allison Deal, Kathe Douglas, Chad V. Pecot, Carrie Lee, Joan Schiller, Nirav Dhruva, Jared Weiss. Frontiers in Oncology, 2021. 8 pages.PMID: 33912470
- Silencing of oncogenic KRAS by mutant-selective small interfering RNA. Bjoern Papke*, Salma H. Azam*, Anne Y. Feng, Amanda E. D. Van Swearingen, Christina Gutierrez-Ford, Pradeep S. Pallan, Martin Egli, Adrienne D. Cox, Channing J. Der, Chad V. Pecot. ACS Pharmacology and Translational Science. 4; 4(2):703-712, 2021. PMID: 33860195 *Contributed Equally #Corresponding Author
- Preparation and Characterization of Poly(2-oxazoline) Micelles for the Solubilization and Delivery of Water Insoluble Drugs. Natasha Vinod, Duhyeong Hwang, Salma H Azam, Amanda E DVan Swearingen, Elizabeth Wayne, Sloane Christian Fussell, Marina Sokolsky-papkov, Chad V. Pecot, Alexander V Kabanov. Bio-Protocols, 2021. 8 pages, PMID: 33855110
- Preparation of an Orthotopic, Syngeneic Model of Lung Adenocarcinoma and the Testing of the Antitumor Efficacy of Poly(2-oxazoline) Formulation of Chemo-and Immunotherapeutic Agents. Natasha Vinod, Duhyeong Hwang, Salma H Azam, Amanda E DVan Swearingen, Elizabeth Wayne, Sloane Christian Fussell, Marina Sokolsky-papkov, Chad V. Pecot, Alexander V Kabanov. Bio-Protocols, 2021. 8 pages, PMID: 33855115
- Tumor-targeted gene therapy with lipid nanoparticles inhibits tumor-associated adipocytes and remodels the immunosuppressive tumor microenvironment in triple-negative breast cancer. Yun Liu, Karthik Tiruthanni, Menglin Wang, Xuefei Zhou, Nasha Qiu, Yang Xiong, Chad V Pecot, Rihe Liu, Leaf Huang. Nanoscale Horizons, 2021. 8 pages. PMID: 33587080
- RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry. April E. Deveaux, Tyler A. Allen, Muthana Al Abo, Xiaodi Qin, Dadong Zhang, Brendon M. Patierno, Lin Gu, Jhanelle E. Gray, Chad V Pecot, Holly K. Dressman, Shannon J. McCall, Rick A. Kittles,Terry Hyslop, Kouros Owzar, Jeffrey Crawford, Steven R. Patierno, Jeffrey M. Clarke, Jennifer A.Freedman. Lung Cancer, 2021. 8 pages.PMID:33465699
2020
- A circle RNA regulatory axis promotes lung squamous metastasis via CDR1-mediated regulation of Golgi trafficking.Harrison EB, Porrello A, Bowman BM, Belanger AR, Yacovone G, Azam SH, Windham IA, Ghosh SK, Wang M, McKenzie N, Waugh TA, Van Swearingen AED, Cohen SM, Allen DG, Goodwin TJ, Mascenik T, Bear JE, Cohen S, Randell SH, Massion PP, Major MB, Huang L, Pecot CV. Cancer Research. 2020 Sep 25:canres.1162.2020. doi: 10.1158/0008-5472.CAN-20-1162. Online ahead of print.PMID: 32978168
- Targeting Epigenetics in Lung Cancer.Chao YL, Pecot CV. Cold Spring Harbor Perspectives in Medicine. 2020 Sep 8:a038000. doi: 10.1101/cshperspect.a038000. Online ahead of print.PMID: 32900703
- Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion.Tagliatela AC, Hempstead SC, Hibshman PS, Hockenberry MA, Brighton HE, Pecot CV, Bear JE. Scientific Reports. 2020 Jul 20;10(1):11958. doi: 10.1038/s41598-020-67465-w.PMID: 32686704
- High-capacity poly(2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of lung adenocarcinoma.Vinod N, Hwang D, Azam SH, Van Swearingen AED, Wayne E, Fussell SC, Sokolsky-Papkov M, Pecot CV, Kabanov AV. Science Advances. 2020 Jun 17;6(25):eaba5542. doi: 10.1126/sciadv.aba5542. eCollection 2020 Jun.PMID: 32596460
- Pulmonary Delivery of Nanoparticle-Bound Toll-like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer.Perry JL, Tian S, Sengottuvel N, Harrison EB, Gorentla BK, Kapadia CH, Cheng N, Luft JC, Ting JP, DeSimone JM, Pecot CV. ACS Nano. 2020 Jun 23;14(6):7200-7215. doi: 10.1021/acsnano.0c02207. Epub 2020 Jun 2.PMID: 32463690
2019
- Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes. Leslie PL, Chao YL, Tsai YH, Ghosh SK, Porrello A, Van Swearingen AED, Harrison EB, Cooley BC, Parker JS, Carey LA, Pecot CV. Nature Communications. 2019 Sep 13;10(1):4192.
- Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis. Azam SH, Porrello A, Harrison EB, Leslie PL, Liu X, Waugh TA, Belanger A, Mangala LS, Lopez-Berestein G, Wilson HL, McCann JV, Kim WY, Sood AK, Liu J, Dudley AC, Pecot CV. Oncogene. 2019 Jun
- Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1. McCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC. Journal of Clinical Investigation. 2019 Mar 11
- Phase II study of stereotactic radiosurgery for the treatment of patients with oligoprogression on erlotinib. Weiss J, Kavanagh B, Deal A, Villaruz L, Stevenson J, Camidge R, Borghaei H, West J, Kirpalani P, Morris D, Lee C, Pecot CV, Zagar T, Stinchcombe T, Pennell N. Cancer Treat Res Commun. 2019 Feb 26.
- Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity. Miret JJ, Kirschmeier P, Koyama S, Zhu M, Li YY, Naito Y, Wu M, Malladi VS, Huang W, Walker W, Palakurthi S, Dranoff G, Hammerman PS, Pecot CV, Wong KK, Akbay EA. Journal of Immunotherapy in Cancer. 2019
2018
- KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Vaseva AV, Blake DR, Gilbert TSK, Ng S, Hostetter G, Azam SH, Ozkan-Dagliyan I, Gautam P, Bryant KL, Pearce KH, Herring LE, Han H, Graves LM, Witkiewicz AK, Knudsen ES, Pecot CV, Rashid N, Houghton PJ, Wennerberg K, Cox AD, Der CJ. Cancer Cell. 2018 Nov 12
- Immunotherapy combinations emerging in non-small-cell lung cancer. Chao YL, Pecot CV.Immunotherapy. 2018 Jun
- A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. Bensen JT, Graff M, Young KL, Sethupathy P, Parker J, Pecot CV, Currin K, Haddad SA, Ruiz-Narváez EA, Haiman CA, Hong CC, Sucheston-Campbell LE, Zhu Q, Liu S, Yao S, Bandera EV, Rosenberg L, Lunetta KL, Ambrosone CB, Palmer JR, Troester MA, Olshan AF. Breast Cancer Res. 2018 Jun
- Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Porrello A, Leslie PL, Harrison EB, Gorentla BK, Kattula S, Ghosh SK, Azam SH, Holtzhausen A, Chao YL, Hayward MC, Waugh TA, Bae S, Godfrey V, Randell SH, Oderup C, Makowski L, Weiss J, Wilkerson MD, Hayes DN, Earp HS, Baldwin AS, Wolberg AS, Pecot CV. Nat Commun. 2018 May 18
- Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment. Harrison EB, Azam SH, Pecot CV. Front Pharmacol. 2018 Apr 4
- Incorporating Pericytes into an Endothelial Cell Bead Sprouting Assay. Azam SH, Smith M, Somasundaram V, Pecot CV. J Vis Exp. 2018 Feb 16
2017
- Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location. Perry JL, Reuter KG, Luft JC, Pecot CV, Zamboni W, DeSimone JM. Nano Lett. 2017 May 10
- Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers. Van Roosbroeck K, Fanini F, Setoyama T, Ivan C, Rodriguez-Aguayo C, Fuentes-Mattei E, Xiao L, Vannini I, Redis RS, D’Abundo L, Zhang X, Nicoloso MS, Rossi S, Gonzalez-Villasana V, Rupaimoole R, Ferracin M, Morabito F, Neri A, Ruvolo PP, Ruvolo VR, Pecot CV, Amadori D, Abruzzo L, Calin S, Wang X, You MJ, Ferrajoli A, Orlowski R, Plunkett W, Lichtenberg TM, Davuluri RV, Berindan-Neagoe I, Negrini M, Wistuba II, Kantarjian HM, Sood AK, Lopez-Berestein G, Keating MJ, Fabbri M, Calin GA. Clin Cancer Res. 2017 Jun 1
2016
- FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK. J Clin Invest. 2016 May 2
- A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK. Nat Commun. 2016 Apr 4
- miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer. Pan Y, Robertson G, Pedersen L, Lim E, Hernandez-Herrera A, Rowat AC, Patil SL, Chan CK, Wen Y, Zhang X, Basu-Roy U, Mansukhani A, Chu A, Sipahimalani P, Bowlby R, Brooks D, Thiessen N, Coarfa C, Ma Y, Moore RA, Schein JE, Mungall AJ, Liu J, Pecot CV, Sood AK, Jones SJ, Marra MA, Gunaratne PH. Oncotarget. 2016 May 3
- Cancer’s got nerve: Schwann cells drive perineural invasion. Azam SH, Pecot CV. J Clin Invest. 2016 Apr 1
- Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer. Seviour EG, Sehgal V, Lu Y, Luo Z, Moss T, Zhang F, Hill SM, Liu W, Maiti SN, Cooper L, Azencot R, Lopez-Berestein G, Rodriguez-Aguayo C, Roopaimoole R, Pecot CV, Sood AK, Mukherjee S, Gray JW, Mills GB, Ram PT. Oncogene. 2016 Feb 11
- Role of Increased n-acetylaspartate Levels in Cancer. Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK. J Natl Cancer Inst. 2016 Jan 26
- Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK. Oncogene. 2016 Aug
- Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients With Lung Adenocarcinoma. Lou Y, Pecot CV, Tran HT, DeVito VJ, Tang XM, Heymach JV, Luthra R, Wistuba II, Zuo Z, Tsao AS. Clin Lung Cancer. 2016 Mar
2015
- A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. Shields BB, Pecot CV, Gao H, McMillan E, Potts M, Nagel C, Purinton S, Wang Y, Ivan C, Kim HS, Borkowski RJ, Khan S, Rodriguez-Aguayo C, Lopez-Berestein G, Lea J, Gazdar A, Baggerly KA, Sood AK, White MA. Mol Syst Biol. 2015 Dec 11
- Erythropoietin Stimulates Tumor Growth via EphB4. Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK. Cancer Cell. 2015 Nov 9;28(5):610-622. doi: 10.1016/j.ccell.2015.09.008. Epub 2015 Oct 17
- Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers. Liu G, Yang D, Rupaimoole R, Pecot CV, Sun Y, Mangala LS, Li X, Ji P, Cogdell D, Hu L, Wang Y, Rodriguez-Aguayo C, Lopez-Berestein G, Shmulevich I, De Cecco L, Chen K, Mezzanzanica D, Xue F, Sood AK, Zhang W. J Natl Cancer Inst. 2015 May 20
2014
- Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers. Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB. Cancer Cell. 2014 Dec 8
- Differential platelet levels affect response to taxane-based therapy in ovarian cancer. Bottsford-Miller J, Choi HJ, Dalton HJ, Stone RL, Cho MS, Haemmerle M, Nick AM, Pradeep S, Zand B, Previs RA, Pecot CV, Crane EK, Hu W, Lutgendorf SK, Afshar-Kharghan V, Sood AK. Clin Cancer Res. 2015 Feb 1
- Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER. van den Beucken T, Koch E, Chu K, Rupaimoole R, Prickaerts P, Adriaens M, Voncken JW, Harris AL, Buffa FM, Haider S, Starmans MHW, Yao CQ, Ivan M, Ivan C, Pecot CV, Boutros PC, Sood AK, Koritzinsky M, Wouters BG. Nat Commun. 2014 Oct 29
- Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK. Nat Commun. 2014 Oct 29
- Therapeutic silencing of KRAS using systemically delivered siRNAs. Pecot CV, Wu SY, Bellister S, Filant J, Rupaimoole R, Hisamatsu T, Bhattacharya R, Maharaj A, Azam S, Rodriguez-Aguayo C, Nagaraja AS, Morelli MP, Gharpure KM, Waugh TA, Gonzalez-Villasana V, Zand B, Dalton HJ, Kopetz S, Lopez-Berestein G, Ellis LM, Sood AK. Mol Cancer Ther. 2014 Dec
- Hematogenous metastasis of ovarian cancer: rethinking mode of spread. Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK. Cancer Cell. 2014 Jul 14
- Notch3 pathway alterations in ovarian cancer. Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK. Cancer Res. 2014 Jun 15
- Antagonism of tumoral prolactin receptor promotes autophagy-related cell death. Wen Y, Zand B, Ozpolat B, Szczepanski MJ, Lu C, Yuca E, Carroll AR, Alpay N, Bartholomeusz C, Tekedereli I, Kang Y, Rupaimoole R, Pecot CV, Dalton HJ, Hernandez A, Lokshin A, Lutgendorf SK, Liu J, Hittelman WN, Chen WY, Lopez-Berestein G, Szajnik M, Ueno NT, Coleman RL, Sood AK. Cell Rep. 2014 Apr 24
- 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK. Nat Commun. 2014 Mar 12
- Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib. Huang J, Hu W, Bottsford-Miller J, Liu T, Han HD, Zand B, Pradeep S, Roh JW, Thanapprapasr D, Dalton HJ, Pecot CV, Rupaimoole R, Lu C, Fellman B, Urbauer D, Kang Y, Jennings NB, Huang L, Deavers MT, Broaddus R, Coleman RL, Sood AK. Clin Cancer Res. 2014 Apr 1
2013
- Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Cell. 2013 Oct 24
- Targeting SRC and tubulin in mucinous ovarian carcinoma. Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK. Clin Cancer Res. 2013 Dec 1
- Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. Kang Y, Hu W, Ivan C, Dalton HJ, Miyake T, Pecot CV, Zand B, Liu T, Huang J, Jennings NB, Rupaimoole R, Taylor M, Pradeep S, Wu SY, Lu C, Wen Y, Huang J, Liu J, Sood AK. J Natl Cancer Inst. 2013 Oct 2
- Tumour angiogenesis regulation by the miR-200 family. Pecot CV, Rupaimoole R, Yang D, Akbani R, Ivan C, Lu C, Wu S, Han HD, Shah MY, Rodriguez-Aguayo C, Bottsford-Miller J, Liu Y, Kim SB, Unruh A, Gonzalez-Villasana V, Huang L, Zand B, Moreno-Smith M, Mangala LS, Taylor M, Dalton HJ, Sehgal V, Wen Y, Kang Y, Baggerly KA, Lee JS, Ram PT, Ravoori MK, Kundra V, Zhang X, Ali-Fehmi R, Gonzalez-Angulo AM, Massion PP, Calin GA, Lopez-Berestein G, Zhang W, Sood AK. Nat Commun. 2013
- Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. Nishimura M, Jung EJ, Shah MY, Lu C, Spizzo R, Shimizu M, Han HD, Ivan C, Rossi S, Zhang X, Nicoloso MS, Wu SY, Almeida MI, Bottsford-Miller J, Pecot CV, Zand B, Matsuo K, Shahzad MM, Jennings NB, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Calin GA. Cancer Discov. 2013 Nov
- Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer. Yang D, Sun Y, Hu L, Zheng H, Ji P, Pecot CV, Zhao Y, Reynolds S, Cheng H, Rupaimoole R, Cogdell D, Nykter M, Broaddus R, Rodriguez-Aguayo C, Lopez-Berestein G, Liu J, Shmulevich I, Sood AK, Chen K, Zhang W. Cancer Cell. 2013 Feb 11
2012
- Metronomic activity of CD44-targeted hyaluronic acid-paclitaxel in ovarian carcinoma. Lee SJ, Ghosh SC, Han HD, Stone RL, Bottsford-Miller J, Shen DY, Auzenne EJ, Lopez-Araujo A, Lu C, Nishimura M, Pecot CV, Zand B, Thanapprapasr D, Jennings NB, Kang Y, Huang J, Hu W, Klostergaard J, Sood AK. Clin Cancer Res. 2012 Aug 1
- Added value of a serum proteomic signature in the diagnostic evaluation of lung nodules. Pecot CV, Li M, Zhang XJ, Rajanbabu R, Calitri C, Bungum A, Jett JR, Putnam JB, Callaway-Lane C, Deppen S, Grogan EL, Carbone DP, Worrell JA, Moons KG, Shyr Y, Massion PP. Cancer Epidemiol Biomarkers Prev. 2012 May
- Paraneoplastic thrombocytosis in ovarian cancer. Stone RL, Nick AM, McNeish IA, Balkwill F, Han HD, Bottsford-Miller J, Rupairmoole R, Armaiz-Pena GN, Pecot CV, Coward J, Deavers MT, Vasquez HG, Urbauer D, Landen CN, Hu W, Gershenson H, Matsuo K, Shahzad MM, King ER, Tekedereli I, Ozpolat B, Ahn EH, Bond VK, Wang R, Drew AF, Gushiken F, Lamkin D, Collins K, DeGeest K, Lutgendorf SK, Chiu W, Lopez-Berestein G, Afshar-Kharghan V, Sood AK. N Engl J Med. 2012 Feb 16
2011
- A novel platform for detection of CK+ and CK- CTCs. Pecot CV, Bischoff FZ, Mayer JA, Wong KL, Pham T, Bottsford-Miller J, Stone RL, Lin YG, Jaladurgam P, Roh JW, Goodman BW, Merritt WM, Pircher TJ, Mikolajczyk SD, Nick AM, Celestino J, Eng C, Ellis LM, Deavers MT, Sood AK. Cancer Discov. 2011 Dec
- Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles. Shahzad MM, Mangala LS, Han HD, Lu C, Bottsford-Miller J, Nishimura M, Mora EM, Lee JW, Stone RL, Pecot CV, Thanapprapasr D, Roh JW, Gaur P, Nair MP, Park YY, Sabnis N, Deavers MT, Lee JS, Ellis LM, Lopez-Berestein G, McConathy WJ, Prokai L, Lacko AG, Sood AK. Neoplasia. 2011 Apr
- RNA interference in the clinic: challenges and future directions. Pecot CV, Calin GA, Coleman RL, Lopez-Berestein G, Sood AK. Nat Rev Cancer. 2011 Jan
2010
- Diagnostic characteristics of a serum biomarker in patients with positron emission tomography scans. Grogan EL, Deppen S, Pecot CV, Putnam JB Jr, Nesbitt JC, Shyr Y, Rajanbabu R, Ory B, Lambright ES, Massion PP. Ann Thorac Surg. 2010 Jun
2009
- A very late stent thrombosis in a patient with diabetes: a call for lifelong dual anti-platelet therapy. Pecot CV, Fuller M, Muldowney JA 3rd, Misra S. Tenn Med. 2009 May