Publications
To view all of Dr. Perou’s publications visit: PubMed
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Aleix Prat, Et al. | Development and validation of the new HER2DX assay for predicting pathological response and survival outcome in early-stage HER2-positive breast cancer | The Lancet | 2022 | |
| Joe Dennis, Et al. | Rare germline copy number variants (CNVs) and breast cancer risk | Communications Biology | 2022 | |
| Jonathan H. Shepherd, Et al. | CALGB 40603 (Alliance): Long-Term Outcomes and Genomic Correlates of Response and Survival After Neoadjuvant Chemotherapy With or Without Carboplatin and Bevacizumab in Triple-Negative Breast Cancer |
Journal of Clinical Oncology | 2022 | |
| Siegel, R.L., Et al. | Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis | Nature | 2022 | |
| Andrea Walens, Et. al. | RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer | American Association for Cancer Research | 2022 | |
| Alina M. Hamilton, Et al. | The landscape of immune microenvironments in racially-diverse breast cancer patients | American Association for Cancer Research | 2022 | |
| Amber N. Hurson, Et al. | Prognostic significance of RNA-based TP53 pathway function among estrogen receptor positive and negative breast cancer cases | Nature | 2022 | |
| Sarah Asad, Et al. | Challenges and Gaps in Clinical Trial Genomic Data Management | American Society of Clinical Oncology | 2022 | |
| Aatish Thennavan, Et al. | Molecular signatures of in situ to invasive progression for basal-like breast cancers: An integrated mouse model and human DCIS study | Nature | 2022 | |
| Youli Xia, Et al. | Integrated DNA and RNA Sequencing Reveals Drivers of Endocrine Resistance in Estrogen Receptor–Positive Breast Cancer | American Association for Cancer Research | 2022 | |
| Xiaoliang Wang, Et al. | Genome‑wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women | Nature | 2022 | |
| Aleix Prat, Et al. | Development andvalidationofthenewHER2DXassay for predicting pathological response and survival outcome in early-stageHER2-positive breast cancer | The Lancet Oncology | 2022 | |
| Fara Braso-Maristany, Et al. | HER2DX ERBB2 mRNA expression in advanced HER2-positive breast cancer treated with T-DM1 | Journal of the National Cancer Institute | 2022 | |
| Valentina Guarneri, Et al. | HER2DX genomic test in HER2-positive/hormone receptor-positive breast cancer treated with neoadjuvant trastuzumab and pertuzumab: A correlative analysis from the PerELISA trial | Ebiomedicine | 2022 | |
| Carey K Anders, Et al. | Evaluating the efficacy of a priming dose of cyclophosphamide prior to pembrolizumab to treat metastatic triple negative breast cancer | Journal for Immunotherapy of Cancer | 2022 | |
| Swarnima Singh, Et al. | Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer | Cancer Research | 2022 | |
| Danielle M. File, Et al. | Clinical subtype, treatment response, and survival in De Novo and recurrent metastatic breast cancer | Breast Cancer Research and Treatment | 2022 | |
| Sonam Bhatia, Et al. | Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics | Cancer Research | 2022 | |
| Jung, A. Y., Et al. | Distinct reproductive risk profiles for intrinsic-like breast cancer subtypes: pooled analysis of population-based studies | Journal of the National Cancer Institute | 2022 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Tomas Pascual, Et al. | Independent Validation of the PAM50-Based Chemo-Endocrine Score (CES) in Hormone Receptor-Positive HER2-Positive Breast Cancer Treated with Neoadjuvant Anti–HER2-Based Therapy | American Association for Cancer Research | 2021 | |
| Lindsay M. Morton, Et al. | Radiation-related genomic profile of papillary thyroid carcinoma after the Chernobyl accident | Science | 2021 | |
| Tom Walsh, Et al. | Inherited predisposition to breast cancer in the Carolina Breast Cancer Study | Nature | 2021 | |
| Amber N. Hurson, Et al. | TP53 pathway function, estrogen receptor status, and breast cancer risk factors in the Carolina Breast Cancer Study | American Association for Cancer Research | 2021 | |
| Iain Carmichael, Et al. | Joint and Individual Analysis of Breast Cancer Histologic Images and Genomic Covariates | The Annuals of Applied Statistics | 2021 | |
| Feng Bai, Et al. | PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors | Breast Cancer Research | 2021 | |
| Nuria Chic, Et al. | Oestrogen receptor activity in hormone-dependent breast cancer during chemotherapy | Elsevier | 2021 | |
| Binita Chakraborty, Et al. | Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma | The Journal of Clinical Investigation | 2021 | |
| Patrick D Radler, Et al. | Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells | Nature Communications | 2021 | |
| Andrew S. Truong, Et al. | Entinostat induces antitumor immune responses through immune editing of tumor neoantigens | The Journal of Clinical Investigation | 2021 | |
| Matthew J. Regner, Et al. | A multi-omic single-cell landscape of human gynecologic malignancies | Molecular Cell | 2021 | |
| Aatish Thennavan, Et al. | Molecular analysis of TCGA breast cancer histologic types | Cell Genomics | 2021 | |
| Yundong He, Et al. | FOXA1 overexpression suppresses interferon signaling and immune response in cancer | The Journal of Clinical Investigation | 2021 | |
| Achal Patel, Et al. | Gene level germline contributions to clinical risk of recurrence scores in Black and White breast cancer patients | American Association for Cancer Research | 2021 | |
| Yang Gao, Et al. | Tumor Suppressor PLK2 May Serve as a Biomarker in Triple-Negative Breast Cancer for Improved Response to PLK1 Therapeutics | American Association for Cancer Research | 2021 | |
| Sunny Z. Wu, Et al. | A single-cell and spatially resolved atlas of human breast cancers | Nature Genetics | 2021 | |
| Siyao Liu, Et al. | MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data | Genome Biology | 2021 | |
| Sung Gwe Ahn, Et al. | Clinical and genomic assessment of PD‑L1 SP142 expression in triple‑negative breast cancer | Springer | 2021 | |
| Sarah C. Vick, Et al. | Anti-PD-1 Checkpoint Therapy Can Promote the Function and Survival of Regulatory T Cells | The Journal of Immunology | 2021 | |
| Jiehui Deng, Et al. | ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer | Nature Cancer | 2021 | |
| Nathan F. Schachter, Et al. | Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer | Nature Communications | 2021 | |
| Steven P. Angus, Et al. | FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036 | Nature Partner Journals | 2021 | |
| Chengheng Liao, Et al. | Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers | American Association for Cancer Research | 2021 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Aranzazu Fernandez-Martinez, MD, Et al. | Survival, Pathologic Response, and Genomics in CALGB 40601 (Alliance), a Neoadjuvant Phase III Trial of Paclitaxel-Trastuzumab With or Without Lapatinib in HER2-Positive Breast Cancer | American Society of Clinical Oncology | 2020 | |
| Chengheng Liao, Et al. | Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer | American Association for Cancer Research | 2020 | |
| Halei C. Benefield, PhD, Et al. | Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features | Oxford University Press | 2020 | |
| Aleix Prat, Et al. | A multivariable prognostic score to guide systemic therapy in early-stage HER2-positive breast cancer: a retrospective study with an external evaluation | The Lancet Oncology | 2020 | |
| Daniel J. Luckett, Et al. | Receiver operating characteristic curves and confidence bands for support vector machines | Biometric Methodology | 2020 | |
| Erika J. Crosby, Et al. | Stimulation of Oncogene-Specific Tumor-Infiltrating T Cells through Combined Vaccine and  Enable Sustained Antitumor Responses against Established HER2 Breast Cancer |
American Association for Cancer Research | 2020 | |
| Multiple Authors | Combined associations of a polygenic risk score and classical risk factors with breast cancer risk | Oxford University Press | 2020 | |
| Multiple Authors | Pan-cancer analysis of whole genomes | Nature | 2020 | |
| E.L. Mayer, Et al. | TBCRC 030: a phase II study of preoperative cisplatin versus paclitaxel in triple-negative breast cancer: evaluating the homologous recombination deficiency (HRD) biomarker | Elsevier | 2020 | |
| Jiehui Deng, Et al. | Serial single‑cell profiling analysis of metastatic TNBC during Nab‑paclitaxel and pembrolizumab treatment | Springer Nature | 2020 | |
| Yongchao Dou, Et al. | Proteogenomic Characterization of Endometrial Carcinoma | Cell | 2020 | |
| Kimberly H. Allison, MD, Et al. | Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update | Journal of Clinical Oncology | 2020 | |
| Arran K. Turnbull, Et al. | Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: comparison of gene expression profiling approaches | BMC Bioinformatics | 2020 | |
| Francesco Schettini, Et al. | HER2-enriched subtype and pathological complete response in HER2-positive breast cancer: A systematic review and meta-analysis | Elsevier | 2020 | |
| Shankha Satpathy, Et al. | Microscaled proteogenomic methods for precision oncology | Nature Communications | 2020 | |
| Meichen Dong, Et al. | SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references | Oxford University Press | 2020 | |
| Sara R. Selitsky, Et al. | Virus expression detection reveals RNAsequencing contamination in TCGA | BMC Genomics | 2020 | |
| Arian Lundberg, Et al. | A pan-cancer analysis of the frequency of DNA alterations across cell cycle activity levels | Springer Nature | 2020 | |
| Susana Garcia-Recio, Et al. | FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease | The Journal of Clinical Investigation | 2020 | |
| Arjun Bhattacharya, Et al. | A framework for transcriptome-wide association studies in breast cancer in diverse study populations | Genome Biology | 2020 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Halei C. Benefield, Et al. | Borderline estrogen receptor-positive breast cancers in black and white women | Journal of the National Cancer Institute | 2019 | |
| Emma H. Allott, Et al. | Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications | Breast Cancer Research and Treatment | 2019 | |
| Emma H. Allott, Et al. | Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium | Springer Nature | 2019 | |
| Pooja Middha Kapoor, Et al. | Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium | International Journal of Epidemiology | 2019 | |
| Lisle E Mose, Charles M Perou, and Joel S Parker | Improved indel detection in DNA and RNA via realignment with ABRA2 | Bioinformatics | 2019 | |
| Kin Yau Wong, Et al. | I-Boost: an integrative boosting approach for predicting survival time with multiple genomics platforms | Genome Biology | 2019 | |
| Mohammad A. Alzubi, Et al. | Separation of breast cancer and organ microenvironment transcriptomes in metastases | Breast Cancer Research | 2019 | |
| Arian Lundberg, Et al. | The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours | Breast Cancer Research | 2019 | |
| Lindsay A. Williams, Et al. | Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas | Cancer Causes & Control | 2019 | |
| Anonymous Authors | Task-Driven Deep Canonical Correlation Analysis | Under review | 2019 | |
| Daniel P. Hollern, Et al. | B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer | Cell | 2019 | |
| Lindsay A. Williams, Katherine A. Hoadley, Et al. | Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas | Springer Nature | 2019 | |
| Arian Lundberg, Et al. | The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours | Breast Cancer Research | 2019 | |
| Youli Xia, Cheng Fan, Et al. | Genetic determinants of the molecular portraits of epithelial cancers | Nature Communications | 2019 | |
| Anonymous Authors | Task-Driven Canonical Correlation Analysis | Anonymous Institution | 2019 | |
| Adrienne G. Waks, Et al. | The immune microenvironment in hormone receptor-positive breast cancer before and after preoperative chemotherapy | AACR Publications | 2019 | |
| Yao Jiang, Et al. | MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression | Nature Communications | 2019 | |
| Adam D. Pfefferle, Et al. | The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor | The Company of Biologists | 2019 | |
| Mohammad A. Alzubi, Et al. | Separation of breast cancer and organ microenvironment transcriptomes in metastases | Breast Cancer Research | 2019 | |
| Glada Zurlo, Et al. | Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer | Nature Communications | 2019 | |
| A.C. Picornell, Et al. | Breast cancer PAM50 signature: correlation and concordance between RNA-Seq and digital multiplexed gene expression technologies in a triple negative breast cancer series | BMC Genomics | 2019 | |
| S. J. Kim, Et al. | Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression | Springer Nature | 2019 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Julija Hmeljak, Et al. | Integrative Molecular Characterization of Malignant Pleural Mesothelioma | Cancer Discovery | 2018 | PubMed |
| Maki Tanioka, Et al. | Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer | Genome Medicine | 2018 | |
| Daniel P. Hollern, Et al. | A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer | Breast Cancer Research and Treatment | 2018 | |
| Yeji An, Et al. | Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast | Cell Reports | 2018 | PubMed |
| Xiang Shu, Et al. | Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis | International Journal of Epidemiology | 2018 | |
| Heather D. Couture, et al. | Multiple Instance Learning for Heterogeneous Images: Training a CNN for Histopathology | International Conference on Medical Image Computing and Computer-Assisted Intervention | 2018 | |
| Heather D. Couture, Et al. | Image analysis with deep learning to predict breast cancer grade, ER status, histologic subtype, and intrinsic subtype | Nature | 2018 | |
| Jonathan T. Lei, Et al. | Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer | Cell Reports | 2018 | |
| Rajshekhar R. Giraddi, Et al. | Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development | Cell Reports | 2018 | |
| Tuan M. Nguyen, Et al. | FGFR1-activated Translation of WNT Pathway Components with Structured 5′ UTRs is Vulnerable to Inhibition of EIF4A-dependent Translation Initiation | AACR Publications | 2018 | |
| Priyanka Sharma, Et al. | Pathological response and survival in triple-negative breast cancer following neoadjuvant carboplatin plus docetaxel | AACR Publications | 2018 | |
| Maki Tanioka, Et al. | Integrated Analysis of RNA and DNA from the Phase III Trial CALGB 40601 Identifies Predictors of Response to Trastuzmab-Based Neoadjuvant Chemotherpy in HER2-Positive Breast Cancer | AACR Publications | 2018 | |
| Jing Zhang, Et al. | VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma | Science | 2018 | |
| Neelam V. Desai, Et al. | Intrinsic molecular subtypes of breast cancers categorized as HER2-positive using an alternative chromosome 17 probe assay | Breast Cancer Research | 2018 | |
| Lindsay A. Williams, Et al. | TP53 protein levels, RNA-based pathway assessment, and race among invasive breast cancer cases” | Nature | 2018 | |
| Hui Shen, Et al. | Integrated Molecular Characterization of Testicular Germ Cell Tumors | Cell Reports | 2018 | PubMed |
| Juan Miguel Cejalvo, Et al. | Clinical implications of the non-luminal intrinsic subtypes in hormone receptor-positive breast cancer | ELSEVIER | 2018 | |
| Andrew Tutt, Et al. | Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial | Nature Medicine | 2018 | |
| Samantha Puvanesrajah, Et al. | PAM50 and risk of recurrence scores for interval breast cancers | Cancer Prevention Research | 2018 | |
| Katherine A. Hoadley, Et al. | Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer | Cell | 2018 | PubMed |
| Isabel Echavarria, Et al. | Pathological Response in a Triple-Negative Breast Cancer Cohort Treated with Neoadjuvant Carboplatin and Docetaxel According to Lehmann’s Refined Classification | Clinical Cancer Research | 2018 | |
| Motoki Takaku, Et al. | GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network | Nature Communications | 2018 | |
| Alexandra Thomas, Et al. | Tumor mutational burden is a determinant of immune-mediated survival in breast cancer | OncoImmunology | 2018 | PubMed |
| Marni B. Siegel, Et al. | Integrated RNA and DNA Sequencing Reveals Early Drivers of Metastatic Breast Cancer | The Journal of Clinical Investigation | 2018 | |
| Wei Sun, Et al. | The association between copy number aberration, DNA methylation and gene expression in tumor samples | Nucleic Acids Research | 2018 | |
| Marni B. Siegel, Et al. | Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer |
2018 | ||
| Simon R. V. Knott, Et al. | Asparagine bioavailability governs metastasis in a model of breast cancer | Nature | 2018 | |
| Milan Radovich, Et al. | The Integrated Genomic Landscape of Thymic Epithelial Tumors |
Cancer Cell | 2018 | PubMed |
| Emma H. Allott, Et al. | Frequency of breast cancer subtypes among African American women in the AMBER consortium | Breast Cancer Research | 2018 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Emma Nolan, Et al. | Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancerr | Science Translational Medicine | 2017 | |
| Juan M. Cejalvo, Et al. | Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer | Cancer Research | 2017 | |
| Dezheng Huo, Et al. | Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in the Cancer Genome Atlas | JAMA Oncology | 2017 | |
| Hawazin Faruki, Et al. | Lung Adenocarcinoma and Squamous Cell Carcinoma Gene Expression Subtypes Demonstrate Significant Differences in Tumor Immune Landscape | JTO | 2017 | |
| Jon S. Zawistowski, Et al. | Enhancer Remodeling during Adaptive Bypass to MEK Inhibition is Attenuated by Pharmacologic Targeting of the P-TEFb Complex | Cancer Discovery | 2017 | |
| K Roarty, Et al. | Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression | Nature | 2017 | |
| Kuan-lin Huang, Et al. | Proteogenomic integration reveals therapeutic targets in breast cancer xenografts | Nature Communications | 2017 | |
| Charles Bowerman, Et al. | Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer | Nano Letters | 2017 | |
| Paola A. Rojas, Et al. | Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness | JNCI | 2017 | |
| Jacquelyn J. Bower, Et al. | Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells | NPJ | 2017 | |
| Gaurav A. Mehta, Et al. | Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer | Breast Cancer Research Treatment | 2017 | |
| Daniel Kechele, Et al. | Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation | Journal of Clinical Investigation | 2017 | |
| Grace O. Silva, Et al. | SynthEx: a synthetic-normal-based DNA sequencing tool for copy number alteration detection and tumor heterogeneity profiling | Genome Biology | 2017 | |
| The Cancer Genome Atlas Research Network | Integrated genomic and molecular characterization of cervical cancer | Genome Biology | 2017 | |
| Farshad Farshidfar, Et al. | Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles | Genome Biology | 2017 | |
| The Cancer Genome Atlas Research Network | Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma | Cell | 2017 | |
| Lauren Fishbein, Et al. | Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma | Cancer Cell | 2017 | |
| Andrew D. Cherniack, Et al. | Integrated Molecular Characterization of Uterine Carcinosarcoma | Cancer Cell | 2017 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Philipp Mertins, Et al. | Proteogenomics connects somatic mutations to signalling in breast cancer |
Macmillan Publishers Limited | 2016 | |
| Haikuo Zhang, Et al. | Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer |
American Association for Cancer Research | 2016 | |
| Michael D. Iglesia, Et al. | Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types | Oxford | 2016 | |
| Zhijian He, Et al. | A high capacity polymeric micelle of paclitaxel: Implication of high dose drug therapy to safety and in vivo anti-cancer activity | Elsevier | 2016 | |
| Jennifer B. Dennison, Et al. | High intra-tumoral stromal content defines Reactive breast cancer as a low-risk breast cancer subtype | American Association for Cancer Research | 2016 | |
| Wei Zhao, Et al. | Identification of mRNA isoform switching in breast cancer | BMC Genomics | 2016 | |
| Michele Ceccarelli, Et al. | Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma | CellPress | 2016 | |
| Joshua D Campbell, Et al. | Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas | Nature Genetics | 2016 | |
| Adam D. Pfefferle, Et al. | Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers | The Company of Biologists | 2016 | |
| Minetta C. Liu, Et al. | PAM50 gene signatures and breast cancer prognosis with adjuvant anthracycline- and taxane-based chemotherapy:correlative analysis of C9741 (Alliance) | npj Breast Cancer | 2016 | |
| Emma H. Allott, Et al. | Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium | Cancer, Epidemiology, Biomarkers & Prevention | 2016 | |
| Priyanka Sharma1, Et al. | Efficacy of neoadjuvant carboplatin plus docetaxel in triple negative breast cancer: Combined analysis of two cohorts | AACR Publications | 2016 | |
| Jerry Usary, David Darr, Adam Pfefferle and Charles Perou | Overview of Genetically Engineered UNIT 14.38 Mouse Models of Distinct Breast Cancer Subtypes | Current Protocols in Pharmacology | 2016 | |
| Michael Iglesia, Et al. | Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types | JNCI | 2016 | |
| Marc A. Becker, Et al. | Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer | PLOS One | 2016 | |
| George W. Sledge, Anees Chagpar and Charles Perou | Collective Wisdom: Lobular Carcinoma of the Breast | ASCO | 2016 | |
| Hui Li, Et al. | MR Imaging Radiomics Signatures for Predicting the Risk of Breast Cancer Recurrence as Given by Research Versions of MammaPrint, Oncotype DX, and PAM50 Gene Assays | Breast Imaging | 2016 | |
| Hui Li, Et al. | Quantitative MRI radiomics in the prediction of molecular classifications of breast cancer subtypes in the TCGA/TCIA data set | npj Breast Cancer | 2016 | |
| Edith A. Perez, Et al. | Intrinsic Subtype and Therapeutic Response Among HER2-Positive Breast Tumors from the NCCTG (Alliance) N9831 Trial |
JNCI | 2016 | |
| Miguel Martin, Et al. | Prognostic ability of EndoPredict compared to research-based versions of the PAM50 risk of recurrence (ROR) scores in nodepositive, estrogen receptor-positive, and HER2-negative breast cancer. A GEICAM/9906 sub-study | Breast Cancer Res. Treat. | 2016 | |
| Campbell D. Lawson, Et al. | Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-activating Proteins in Basal-like Breast Cancers |
AACR | 2016 | |
| Yujing J. Heng, Et al. | The molecular basis of breast cancer pathological phenotypes | Pathology | 2016 | |
| Melissa A. Troester, Et al. | DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas | npj Breast Cancer | 2016 | |
| Cancer Genome Atlas Research Network | Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma | NEJM | 2016 | |
| Lisle E. Mose, Et al. | Assembly-based inference of B-cell receptor repertoires from short read RNA sequencing data with V’DJer |
Bioinformatics Advance Access | 2016 | |
| Aleix Prat, Et al. | A PAM50-Based Chemoendocrine Score for HormoneReceptor–Positive Breast Cancer with an Intermediate Risk of Relapse |
Clinical Cancer Research | 2016 | |
| Denise K. Reaves, Et al. | Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis | Molecular Cancer Research | 2016 | |
| Katherine A. Hoadley, Et al. | NTumor Evolution in Two Patients with Basallike Breast Cancer: A Retrospective Genomics Study of Multiple Metastases | PLOS | 2016 | |
| Charles J. Bowerman, Et al. | Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer | Nano Letters | 2016 |
| AUTHOR | TITLE | JOURNAL | YEAR | DOWNLOAD |
| Justin L. Black, Et al. | CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer |
Breast Cancer Res. Treat. | 2015 | |
| J Knezevic, Et al. | Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential |
Oncogene advance online publication | 2015 | |
| Ze-Yi Zheng, Et al. | Wild-Type N-Ras, Overexpressed in Basal-likeBreast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation |
Cell Reports | 2015 | |
| Pu Wang, Et al. | Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents |
Cell Reports | 2015 | |
| Christian D. Young, Et al. | Activating PIK3CA mutations induce an EGFR/ERK paracrine signaling axis in basal-like breast cancer |
MCP Papers in Press | 2015 | |
| Hisham Mohammed, Et al. | Progesterone receptor modulates ERa action in breast cancer | Nature | 2015 | |
| Kelly V. Ruggles, Et al. | An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer | MCP Papers in Press | 2015 | |
| Christopher Dravis, Et al. | Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells | Cell Reports | 2015 | |
| Giovanni Ciriello, Et al. | Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer |
Cell | 2015 | |
| The Cancer Genome Atlas Network | Genomic Classification of Cutaneous Melanoma | Cell | 2015 | |
| The Cancer Genome Atlas Research Network |
The Molecular Taxonomy of Primary Prostate Cancer | Cell | 2015 | |
| Michael A. Cantrell, Et al. | c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression | Impact Journals | 2015 | |
| J Knezevic1, Et al. | Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential |
Oncogene advance online publication | 2015 | |
| Christian D. Young, Et al. | Activating PIK3CA mutations induce an EGFR/ERK paracrine signaling axis in basal-like breast cancer | MCP Papers in Press | 2015 | |
| Joshua D Welch, Et al. | Pseudogenes transcribed in breast invasive carcinoma show subtype-specific expression and ceRNA potential | BMC Genomics | 2015 | |
| Elvin Wagenblast, Et al. | A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis | Macmillan Publishers | 2015 | |
| William T. Barry, Et al. | The Use of Bayesian Hierarchical Models for Adaptive Randomization in Biomarker-Driven Phase II Studies | Journal of Biopharmaceutical Statistics | 2015 | |
| William F. Anderson, Et al. | Response | JNCI | 2015 | |
| Torsten O. Nielsen and Charles M. Perou | CCR 20th Anniversary Commentary: The Development of Breast Cancer Molecular Subtyping | AACR | 2015 | |
| Adam D. Pfefferle, Et al. | Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy | Breast Cancer Res Treat | 2015 | |
| Mei Zhang, Et al. | Intratumoral heterogeneity in a p53 null mouse model of human breast cancer | Cancer Discovery | 2015 | |
| Zhijian He, Et al. | Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: Preparation, in vitro and in vivo evaluation | Journal of Controlled Release | 2015 | |
| Maggie C.U. Cheang, Et al. | Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor Expression | The Oncologist | 2015 | |
| The Cancer Genome Atlas Network | Comprehensive genomic characterization of head and neck squamous cell carcinomas | Nature | 2015 | |
| Yi-Juan Hu, Et al. | Proper Use of Allele-Specific Expression Improves Statistical Power for cis-eQTL Mapping with RNA-Seq Data | Journal of the American Statistical Association | 2015 | |
| Ligibel, Jennifer A., Et al. | Body Mass Index, PAM50 Subtype, and Outcomes in Node-Positive Breast Cancer: CALGB 9741 (Alliance) | JNCI | 2015 | |
| Carey, Lisa A., Et al. | Molecular Heterogeneity and Response to Neoadjuvant Human Epidermal Growth Factor Receptor 2 Targeting in CALGB 40601, a Randomized Phase III Trial of Paclitaxel Plus Trastuzumab With or Without Lapatinib | Journal of Clinical Oncology | 2015 | |
| Silva, Grace O., Et al. | Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer | Breast Cancer Research Treatment | 2015 | |
| Voduc, K. David, Et al. | αB-crystallin expression in breast cancer is associated with brain metastasis | Nature | 2015 | |
| Allott, Emma H., Et al. | Performance of Three Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium | CEBP | 2015 | |
| Faruki, Hawazin, Et al. | Validation of the Lung Subtyping Panel in Multiple Fresh-Frozen and Formalin-Fixed, Paraffin-Embedded Lung Tumor Gene Expression Data Sets |
Archives of Pathology & Laboratory Medicine | 2015 | |
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| Jason I Herschkowitz, Et al. | Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors | Genome Biology | 2007 | |
| Michael Mullins, Et al. | Agreement in Breast Cancer Classification between Microarray and Quantitative Reverse Transcription PCR from Fresh-Frozen and Formalin-Fixed, Paraffin-Embedded Tissues | Clinical Chemistry | 2007 | |
| Robert C. Millikan, Et al. | Epidemiology of basal-like breast cancer | Breast Cancer Research and Treatment | 2007 | |
| Mark F. Burkart, Et al. | Clustering Microarray-Derived Gene Lists Through Implicit Literature Relationships | Bioinformatics | 2007 | |
| SJ Bultman, Et al. | Characterization of mammary tumors from Brg1 heterozygous mice | Oncogene | 2007 | |
| Jian Jiang, Et al. | Development of an immuno tandem mass spectrometry (iMALDI) assay for EGFR diagnosis | Propeomics Clinical Applications | 2007 | |
| Katherine A Hoadley, Et al. | EGFR associated expression profiles vary with breast tumor subtype | BMC Genomics | 2007 | |
| Sunil Badve, Et al. | FOXA1Expression in Breast CancerCorrelationwith Luminal SubtypeA and Survival |
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| Montserrat Garcia-Closas, Et al. | Common Genetic Variation in GATA-Binding Protein 3 and Differential Susceptibility to Breast Cancer by Estrogen Receptor A Tumor Status | Cancer Epidemiology Biomarkers and Prevention | 2007 | |
| Chad A. Livasy MD, Et al. | Identification of a basal-like subtype of breast ductal carcinoma in situ | Human Pathology | 2007 | |
| Zhe Li, Et al. | ETV6-NTRK3 Fusion Oncogene Initiates Breast Cancer from Committed Mammary Progenitors via Activation of AP1 Complex | Cancer Cell | 2007 | .pdf |
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| Jose V. Moyano, Et al. | B-Crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer | The Journal of Clinical Investigations | 2006 | |
| Michael L. Whitfield, Et al. | Common markers of proliferation | Nature Reviews Cancer | 2006 | |
| V Ciocca, Et al. | Cytokeratin profiles of male breast cancers | Histopathology | 2006 | |
| Daniel S. Oh, Et al. | Estrogen-Regulated Genes Predict Survival in Hormone Receptor–Positive Breast Cancers | Journal of Clinical Oncology | 2006 | |
| Laurent Perreard, Et al. | Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay | Breast Cancer Research | 2006 | |
| Zhiyuan Hu, Et al. | The molecular portraits of breast tumors are conserved across microarray platforms |
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| Lisa A. Carey, Et al. | Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study | JAMA | 2006 | |
| Cheng Fan, Et al. | Concordance among Gene-Expression–Based Predictors for Breast Cancer | MEJM | 2006 | |
| Gro Leite Størvold, Et al. | siRNA: A Potential Tool for Future Breast Cancer Therapy? | Critical Reviews in Oncogenesis | 2006 | |
| Therese Sørlie, Et al. | Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer | Molecular Cancer Therapeutics | 2006 | |
| D. Neil Hayes, Et al. | Gene Expression Profiling Reveals Reproducible Human Lung Adenocarcinoma Subtypes in Multiple Independent Patient Cohorts | Journal of Clinical Oncology | 2006 | |
| Melissa A Troester, Et al. | Gene expression patterns associated with p53 status in breast cancer | BMC Cancer | 2006 | |
| David S. Shames, Et al. | A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies | PLOS Medicine | 2006 |
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| Zhiyuan Hu, Et al. | High reproducibility using sodium hydroxide-stripped long oligonucleotide DNA microarrays | Biotechniques | 2005 | |
| Members of the Toxicogemoics Research Consortium | Standardizing global gene expression analysis between laboratories and across platforms | Nature Methods | 2005 | |
| Roman Rouzier, Et al. | Breast CancerMolecular Subtypes Respond Differently to Preoperative Chemotherapy |
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| Britta Weigelt, Et al. | Molecular Portraits and 70-Gene Prognosis Signature Are Preserved throughout the Metastatic Process of Breast Cancer |
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| Chad A Livasy, Et al. | Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma | Modern Pathology | 2005 |
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| Tatyana A. Grushko, Et al. | MYC Is Amplified in BRCA1-Associated Breast Cancers | Clinical Cancer Research | 2004 | |
| Natalia Novoradovskaya, Et al. | Universal Reference RNA as a standard for microarray experiments | BMC Genomics | 2004 | |
| Christine H. Chung, Et al. | Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression | Cancer Cell | 2004 | |
| Jerry Usary, Et al. | Mutation of GATA3 in human breast tumors | Oncogene | 2004 | |
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| Torsten O. Nielsen, Et al. | Immunohistochemical and Clinical Characterization of the Basal- Like Subtype of Invasive Breast Carcinoma |
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| Melissa A. Troester, Et al. | Prediction of Toxicant-Specific Gene Expression Signatures after Chemotherapeutic Treatment of Breast Cell Lines |
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| Therese Sørlie, Et al. | Repeated observation of breast tumor subtypes in independent gene expression data sets | PNAS | 2003 | |
| Charles M Perou Et al. | DNA microarrays in breast cancer: the promise of personalised medicine | The Lancet | 2003 | |
| Matt van de Rijn, Et al. | Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome | American Journal of Pathology | 2003 | |
| Michael L. Whitfield, Et al. | Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors | Molecular Biology of the Cell | 2002 | |
| Jonathan R. Pollack, Et al. | Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors | PNAS | 2002 | |
| Christine H. Chung, Et al. | Molecular portraits and the family tree of cancer | Nature Genetics | 2002 | |
| Brian S. Finlin, Et al. | RERG Is a Novel ras-related, Estrogen-regulated and Growth-inhibitory Gene in Breast Cancer | The Journal of Biological Chemistry | 2001 | |
| Charles M Perou | Show me the Data! | Nature Genetics | 2001 |