Generation of genetically engineered mice
- Sophisticated targeting allele design and production
- ES production and blastocyst injection
- Transgenic production through pronuclear injection
- GEMM support technologies
- Test novel therapeutics using GEMMs in a manner faithful to human cancers
This core facility is under the direction of faculty directors Bernard Weissman, PhD, and Norman Sharpless, MD, and facility director Dale Cowley, PhD.