43rd Annual UNC Lineberger Scientific Symposium

UNC Lineberger Comprehensive Cancer Center will host its 43rd annual scientific symposium on April 29-30, 2019, at the William and Ida Friday Center for Continuing Education in Chapel Hill, North Carolina.

**Online registration is now closed. Onsite registration will be available.**

Syllabus

“Dysregulated Signaling Pathways in Cancer: Insights into Novel Mechanisms and Therapeutic Approaches”

Organizers

Albert S. Baldwin, PhD, Greg Wang, PhD, Yue Xiong, PhD, and Qing Zhang, PhD

Confirmed Speakers

C. David Allis, PhD
Rockefeller University
“When Genetics and Epigenetics Collide: Insights Gained into Human Cancer”

Scott Armstrong, MD, PhD
Dana-Farber Cancer Institute
“Targeting Chromatin Complexes to Modulate Gene Expression in Cancer”

Arul Chinnaiyan, MD, PhD
University of Michigan
“The Application of Integrative Sequencing for Precision Oncology”

Michael Emanuele, PhD
UNC Lineberger Comprehensive Cancer Center
“Ubiquitin Signaling in Cell Cycle Control and Cancer”

Kun-Liang Guan, PhD
University of California, San Diego
“The Hippo Pathway in Cell Growth, Organ Size, and Tumorigenesis”

Guang Hu, PhD
National Institute of Environmental Health Sciences
“Regulation of the Naïve and Primed Pluripotent State”

William G. Kaelin, Jr, MD
Dana-Farber Cancer Institute
“The von Hippel-Lindau Tumor Suppressor: Insights into Oxygen Sensing and Drugging the Undruggable”

William Kim, MD
UNC Lineberger Comprehensive Cancer Center
“Regulation of the Bladder Cancer Microenvironment”

Christine Lovly, MD
Vanderbilt University
“New Ways to Target EGFR Signaling in Lung Cancer”

Charles Sawyers, MD
Memorial Sloan Kettering Cancer Center
“Lineage Plasticity in Prostate Cancer”

Mario Suva, MD, PhD
Massachusetts General Hospital
“Dissecting Human Gliomas by Single-Cell Genomics”

Cheryl Walker, PhD
Baylor College of Medicine
“A New Role for Epigenetic “Readers, Writers and Erasers” in Cytoskeleton Remodeling”

Greg Wang, PhD
UNC Lineberger Comprehensive Cancer Center
“DNMT3A, de novo DNA Methylation and Blood Cancer”

Yue Xiong, PhD
UNC Lineberger Comprehensive Cancer Center
“TET DNA Dioxygenases in Interferon Signaling and Tumor Immunity”

Jen Jen Yeh, MD
UNC Lineberger Comprehensive Cancer Center
“Pancreatic Cancer Subtypes for Precision Medicine”

Qing Zhang, PhD
UNC Lineberger Comprehensive Cancer Center
“Novel von Hippel-Lindau Regulatory Pathways in Cancer”

Jean Zhao, PhD
Dana-Farber Cancer Institute
“Harnessing the Synergy of Immunotherapy and Targeted Therapy for Cancer Treatment: From Mouse Models to Human Therapy”

Sponsors