Monday, April 29

Time Speaker Title
8:50-9 a.m. H. Shelton Earp, MD
UNC Lineberger Comprehensive Cancer Center
Opening Remarks
9-9:35 a.m. William G. Kaelin, Jr, MD
Dana-Farber Cancer Institute
Lineberger Lecture
The von Hippel-Lindau Tumor Suppressor: Insights into Oxygen Sensing and Drugging the Undruggable
9:35-10 a.m. Qing Zhang, PhD
UNC Lineberger Comprehensive Cancer Center
Novel von Hippel-Lindau Regulatory Pathways in Cancer
10-10:25 a.m. Jen Jen Yeh, MD
UNC Lineberger Comprehensive Cancer Center
Pancreatic Cancer Subtypes for Precision Medicine
10:25-10:55 a.m. Break
10:55-11:20 a.m. William Kim, MD
UNC Lineberger Comprehensive Cancer Center
Regulation of the Bladder Cancer Microenvironment
11:20-11:55 a.m. Kun-Liang Guan, PhD
University of California, San Diego
The Hippo Pathway in Cell Growth, Organ Size, and Tumorigenesis
11:55 a.m.-1 p.m. Lunch
1-1:35 p.m. Charles Sawyers, MD
Memorial Sloan Kettering Cancer Center
Lineberger Lecture
Lineage Plasticity in Prostate Cancer
1:35-2:10 p.m. Christine Lovly, MD, PhD
Vanderbilt University
New Ways to Target EGFR Signaling in Lung Cancer
2:10-2:35 p.m. Mike Emanuele, PhD
UNC Lineberger Comprehensive Cancer Center
Ubiquitin Signaling in Cell Cycle Control and Cancer
2:35-3:05 p.m. Break
3:05-3:40 p.m. Mario Suva, PhD
Massachusetts General Hospital
Dissecting human gliomas by single-cell genomics
3:40-4:05 p.m. Guang Hu, PhD
National Institute of Environmental Health Sciences
Regulation of the Naïve and Primed Pluripotent State
4:05-4:40 p.m. Jean Zhao, PhD
Dana-Farber Cancer Institute
Harnessing the Synergy of Immunotherapy and Targeted Therapy for Cancer Treatment: From Mouse Models to Human Therapy
4:40-5:15 p.m. Arul Chinnaiyan, MD, PhD
University of Michigan
The Application of Integrative Sequencing for Precision Oncology


Tuesday, April 30

Time Speaker Title
9-9:35 a.m.
C. David Allis, PhD
Rockefeller University
Lineberger Lecture
When Genetics and Epigenetics collide: Insights Gained into Human Cancer
9:35-10 a.m.
Greg Wang, PhD
UNC Lineberger Comprehensive Cancer Center
DNMT3A, de Novo DNA Methylation and Blood Cancer
10-10:35 a.m.
Cheryl Walker, PhD
Baylor College of Medicine
A New Role for Epigenetic “Readers, Writers and Erasers” in Cytoskeleton Remodeling
10:35-11:05 a.m.
11:05-11:15 a.m.
Company Presentation
11:15-11:40 a.m.
Yue Xiong, PhD
UNC Lineberger Comprehensive Cancer Center
TET DNA Dioxygenases in Interferon Signaling and Tumor Immunity
11:40 a.m.-12:15 p.m.
Scott Armstrong, MD, PhD
Dana-Farber Cancer Institute
Targeting Chromatin Complexes to Modulate Gene Expression in Cancer
12:15-12:30 p.m. Closing Remarks
12:30 p.m.