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Aggressive breast cancer grows faster in obese environment

March 31, 2017

In an abstract presented at the American Association for Cancer Research Annual Meeting 2017, UNC Lineberger’s Liza Makowski, PhD, reported her and her colleagues’ preliminary findings that breast cancer cells grew larger when they were transplanted into fatty, obese tissue.

Spring deadline is March 15 for cancer research grant proposals

February 28, 2017

There are two categories of awards offered this spring for the UNC Lineberger Developmental Funding Award: Pilot Awards of up to $50,000 for one-year projects involving one principal investigator, and Stimulus Awards of up to $100,000 per year for one or two years for projects that enhance our scientific understanding of cancer basic mechanisms or clinical and public health practice.

Pecot awarded $400,000 Free to Breathe grant

January 31, 2017

Funding will support research to evaluate whether targeting inflammatory monocytes through the use of CCR2 inhibitors will blunt or prevent metastasis in squamous cell lung cancer.

With gift of scarves, women address cancer’s impact on image

January 25, 2017

Thanks to the donation of handmade scarves from community groups, UNC Lineberger’s Patient and Family Resource Center staff are helping women to counter some of the side effects of cancer treatments. In addition to receiving a beautiful scarf, the women were taught different ways to wear it.

Researchers unlock mechanism of drug resistance in aggressive breast cancer

January 20, 2017

In the journal Cancer Discovery, UNC Lineberger’s Gary Johnson, PhD, and colleagues published findings on how triple negative breast cancer cells are able to bypass treatment with trametinib, an FDA-approved kinase inhibitor. They also demonstrated in a laboratory model a potential treatment approach that could prevent the onset of resistance.

Inside the world of cell signaling: a G-protein breakthrough

December 21, 2016

Scientists led by UNC Lineberger member John Sondek, PhD, created a new biochemical tool to block specific types of downstream G-protein signaling, opening new avenues of research and potential drug design and discovery.