Researchers unlock mechanism of drug resistance in aggressive breast cancer

January 20, 2017

In the journal Cancer Discovery, UNC Lineberger’s Gary Johnson, PhD, and colleagues published findings on how triple negative breast cancer cells are able to bypass treatment with trametinib, an FDA-approved kinase inhibitor. They also demonstrated in a laboratory model a potential treatment approach that could prevent the onset of resistance.

In memoriam: Oliver Smithies, DPhil

January 11, 2017

UNC Lineberger member and Nobel Laureate Oliver Smithies, DPhil, passed away Jan. 10. UNC Lineberger Director Norman E. Sharpless, MD, said Smithies “played a critical role in the university’s evolution into a world-leading scientific juggernaut.”

Scientists use light to control the logic networks of a cell

January 5, 2017

Scientists at the University of North Carolina at Chapel Hill have developed a method to control proteins inside live cells with the flick of a switch, giving researchers an unprecedented tool for pinpointing the causes of disease using the simplest of tools: light.