Researchers identify traits linked to better outcomes in HPV-linked head and neck cancer

June 13, 2019

Using a new blood test that’s in development, University of North Carolina Lineberger Comprehensive Cancer Center researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection. Researchers believe the findings, published in the journal Clinical Cancer Research, could help identify those … Continued

UNC Lineberger recognizes 2018 Pagano Award recipients

June 10, 2019

UNC Lineberger presented three postdoctoral fellows with the 2018 Joseph S. Pagano Award to recognize their leadership of notable scientific publications. Kirsten Bryant, PhD, Ari Pani, PhD, and John Pryor, PhD, were selected through a competitive process for the honor, which comes with a $2,500 award. The three recipients will be formally recognized in a … Continued

Study co-led by Vincent published in Immunity’s ‘Best of 2018’

June 3, 2019

UNC Lineberger’s Benjamin Vincent, MD, an assistant professor in the UNC School of Medicine Division of Hematology/Oncology, was co-corresponding author of a study included in the journal Immunity’s “Best of 2018” reprint collection.  Jonathan Serody, MD, UNC Lineberger’s associate director for translational sciences and the Elizabeth Thomas Professor of Medicine, Microbiology and Immunology in the … Continued

Scientists uncover mechanism of action for promising cancer compound

May 31, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered the mechanism that explains how an investigational cancer therapeutic might be working – a finding that they believe could be important for the design of potential new therapies. In the journal ACS Chemical Biology, researchers explain how the investigational compound ONC201 may be working … Continued

Melanoma survivor shares story to inspire hope

May 30, 2019

When Judith Edmonds discovered an itchy, raised freckle on her leg, she knew something was wrong. At that time, she didn’t realize how important this was going to be to her life. Edmonds, who now lives in Bullock, N.C., was diagnosed with melanoma, a potentially deadly form of skin cancer, and she had the cancer … Continued

UNC Lineberger researchers convene panel to examine thyroid cancer trends in NC

May 20, 2019

University of North Carolina Lineberger Comprehensive Cancer Center leaders brought together a team of doctors, epidemiologists and environmental scientists on May 13 to discuss patterns and causes of thyroid cancer in North Carolina – a meeting convened in response to community concerns about thyroid cancer trends in Iredell County. Experts from the National Cancer Institute, … Continued

A caring cancer community: mom, daughter support other pediatric patients

May 10, 2019

Lorelei Partin’s cancer journey has led her mom, Katie Ware, to discover a whole new community of friends and a hidden talent for fundraising along the way. Diagnosed two years ago, Lorelei cannot wait to ring the bell to mark the end of her leukemia treatments, but she’s going to miss the people at the N.C. Cancer Hospital’s Pediatric Hematology Oncology Clinic, including her doctor, UNC Lineberger’s Thomas Alexander, MD, MPH.

UNC Lineberger’s research symposium draws more than 500 registrants

May 2, 2019

Can scientists wake up sleeping tumor suppressor molecules in cancer cells? What are the genetic features of cancer cells that contribute to some forms of prostate cancer developing resistance to multiple lines of treatment? Those were some of the topics covered at UNC Lineberger Comprehensive Cancer Center’s 43rd Annual Scientific Symposium at the William & … Continued

Marzluff lab to collaborate on gene editing project

May 2, 2019

UNC Lineberger’s William Marzluff, PhD, William Rand Kenan Professor in the UNC School of Medicine Department of Biochemistry & Biophysics, will collaborate with Research Triangle Park-based Cell Microsystems in an effort to speed the use of CRISPR technology in lab experiments. The company was awarded two federal Small Business Innovation and Research awards totaling $1.9 … Continued

Study provides insights behind hyperactivation of key cell proliferation signal

April 19, 2019

The idea was simple: find the faulty signals that drive cancerous growth in cells, and block them. But what University of North Carolina Lineberger Comprehensive Cancer Center researcher Pengda Liu, PhD, has discovered, when it comes to cancer, even straightforward concepts can become complicated. “When you find a target and inhibit it, you find the … Continued