New details revealed to explain how tumors recruit blood vessels

April 17, 2019

A study by University of North Carolina Lineberger Comprehensive Cancer Center researchers helps explain how tumors recruit blood vessels that provide fuel for their growth as well as an avenue for the tumors to spread. In the journal Oncogene, the researchers also reported they built on these findings to uncover a potential treatment strategy to … Continued

NCI awards $2.2M to Pylayeva-Gupta to investigate immune responses in pancreatic cancer

April 17, 2019

The National Cancer Institute has awarded a five-year grant of more than $2.2 million to UNC Lineberger’s Yuliya Pylayeva-Gupta, PhD, to support her research into the immune response in pancreatic cancer, one of the deadliest cancers. “Understanding the role of immune regulation in pancreatic cancer represents a crucial stepping stone on our way to advancing … Continued

Researchers study strategies for using nanotechnology to boost cancer therapeutics

April 11, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers presented innovative new strategies for using tiny particles – particles the size of a DNA molecule or the width of a human hair – to boost cancer treatment as part of the Carolina Center of Cancer Nanotechnology Excellence/National Cancer Institute site visit on Tuesday. The researchers, … Continued

Estrogen byproducts linked to survival in breast cancer patients

March 31, 2019

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found preliminary evidence that measuring byproducts of the hormone estrogen can help them predict survival for women with breast cancer. In an abstract presented at the American Association for Cancer Research Annual Meeting, researchers report findings from a study in which they measured levels … Continued

Studies explore mechanisms behind obesity-cancer link

March 31, 2019

New studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers explore biological mechanisms behind obesity and its link with cancer. Research findings presented at the American Association for Cancer Research Annual Meeting 2019 explore possible reasons for obesity-related resistance to breast cancer treatment and possible strategies to overcome obesity-related immune suppression in … Continued

UNC Lineberger members to share expertise, findings at AACR Annual Meeting

March 26, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers will share their expertise and latest findings at the American Association for Cancer Research Annual Meeting 2019, which is expected to draw thousands of scientists, physicians, advocates and others to Atlanta March 29-April 3. New findings will be presented revealing insights behind connection between obesity and … Continued

Wang named American Institute for Medical and Biological Engineering fellow

March 26, 2019

WASHINGTON D.C. — The American Institute for Medical and Biological Engineering (AIMBE) has inducted of University of North Carolina Lineberger Comprehensive Cancer Center member Andrew Wang, MD, into its College of Fellows. Wang, an associate professor in the UNC School of Medicine Department of Radiation Oncology and director of clinical and translational research in the … Continued

UNC Lineberger to hold 43rd annual scientific symposium April 29-30

March 19, 2019

The University of North Carolina Lineberger Comprehensive Cancer Center’s 43rd annual Scientific Symposium will feature talks by scientists from UNC Lineberger and from around the country, including three recipients of the prestigious Lasker Award, on the topic of dysregulated signaling in cancer. The symposium, which will be held April 29-30 at the William and Ida … Continued

Scientists discover key enzyme in breast cancer proliferation, treatment resistance

March 12, 2019

Basal-like breast cancer is the most aggressive and difficult-to-treat subtype of breast cancer, and it largely overlaps with the triple-negative classification of the disease. Patients are in dire need of improved therapies that attack the underlying cellular features of these types of breast cancer. Now scientists at the University of North Carolina Lineberger Comprehensive Cancer … Continued