Researchers find clues to drug resistance in medulloblastoma subtype

January 13, 2020

University of North Carolina Lineberger Comprehensive Cancer Center researchers have new evidence to explain how drug resistance develops in a major subtype of medulloblastoma, the most common invasive brain tumor in children. A UNC Lineberger team led by Timothy Gershon, MD, PhD and Kirk Wilhelmsen MD, PhD, reported in the journal Nature Communications that they … Continued

Researchers identify possible approach to block medulloblastoma growth

October 23, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children. UNC Lineberger’s Timothy Gershon, MD, PhD and colleagues reported in the journal Development that by blocking a signal called GSK-3, they could control tumor growth in a … Continued

Grateful patient works with lab team to find cancer therapies

June 28, 2019

Once cancer treatment ends, hopefully with a clean bill of health, most patients hightail it away from the hospital, putting the endless batteries of tests, needle sticks and scans in their rearview mirror. So it’s a rare patient that returns of their own volition, and rarer still, becomes a lab volunteer. But that’s exactly what David Hesmer did.

Removing a brain tumor makes remaining cancer more aggressive

July 5, 2016

A study led by UNC Lineberger member Shawn Hingtgen, PhD, has determined that removing a glioblastoma tumor from the brain causes any cancer left behind to grow much faster than the original tumor did. The findings from the Neuro-Oncology paper illustrate the effect of surgery on the brain and tumor and the need to rethink how to treat the disease differently after the surgery.

Lynn Latchford

March 20, 2015

In early 2013, while pursuing a doctoral degree in theological anthropology at Trinity College in Dublin, Ireland, Lynn Latchford began to experience some puzzling symptoms. Routine academic tasks suddenly became difficult. Mental fogginess was accompanied by fatigue, weight gain and changes in her sense of smell, taste and hearing. Doctors attributed her symptoms to a chronic thyroid disorder and stress.