Findings could help identify which aggressive breast cancers will respond to immune treatments

November 14, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer. The U.S. Food and Drug Administration recently approved a treatment that combines an immunotherapy drug and chemotherapy for triple negative breast cancer, but … Continued

Scientists implicate genes behind faulty DNA repair in breast cancer

September 20, 2019

While mutations in BRCA genes are well known to increase breast cancer risk, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have uncovered a different series of genes they believe might be contributing to breast cancer through a lesser-known mechanism. Mutations in BRCA cause cells to lose the ability to repair errors … Continued

Susan G. Komen awards nearly $1.5M in breast cancer research grants to UNC Lineberger

September 16, 2019

Susan G. Komen® today announced it was providing $1.45 million in research grants to three UNC Lineberger Comprehensive Cancer Center members as part of a national campaign focused on metastatic breast cancer, developing new, more-effective treatments, and addressing disparities in breast cancer outcomes. The grants support Komen’s commitment to achieve its Bold Goal to reduce … Continued

Researchers identify strategy to block immunosuppressive signals in melanoma

September 16, 2019

Cancer cells have a clever approach to avoid key immune cells intent on killing them. Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center report in the journal Cancer Immunology Research they have developed a strategy to shut down signals that keep cancer-killing immune cells from infiltrating melanoma. By blocking receptors on the … Continued

Researchers develop method for identifying aggressive breast cancer drivers

August 13, 2019

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method to precisely identify individual … Continued