Study sheds light on why some breast cancers have limited response to immunotherapy

August 21, 2017

Jonathan Serody, MD, Benjamin Vincent, MD, and a team of UNC Lineberger investigators published findings in the Journal of Clinical Investigation that may explain why drugs designed to unleash the immune system against cancer were ineffective in treating a type of triple negative breast cancer. They determined “claudin-low” tumors were releasing a chemical signal to attract regulatory T-cells, which prevented the immune system from rejecting the cancer.

Breast cancer researchers receive $2.5 million in Susan G. Komen grants

September 19, 2016

Susan G. Komen has announced more than $2.5 million in grants for UNC Lineberger Comprehensive Cancer Center researchers. The organization, which funded eight grants for nearly $2.97 million to researchers in North Carolina, has a goal of reducing breast cancer deaths in the U.S. by 50 percent across the next decade.

On the hunt for genetic clues to breast cancers that spread to the brain

August 11, 2016

UNC Lineberger researcher Carey Anders, MD, wants to understand why some breast cancers metastasize to the brain, and what drives them. She recently was awarded a three-year, $450,000 grant to study genetic features of breast cancer brain metastases to try to answer those questions.

Insurance, distance to care can be barriers to breast reconstruction

July 28, 2016

Researchers say breast reconstruction can help with self-esteem, sexuality and body image after cancer treatment. But a UNC Lineberger study led by Michelle Roughton, MD, has found that the type of insurance a woman has as well as distance to a plastic surgeon’s office can be barriers to the procedure.

UNC Lineberger hosts National Cancer Moonshot regional summit

June 30, 2016

Members from North Carolina’s three National Cancer Institute-designated comprehensive cancer centers, together with care providers, researchers, advocates and patients from the state, met in Chapel Hill to be part of a national discussion on how to speed the pace of cancer discovery and clinical advances.

UNC Lineberger hosts Cancer Moonshoot regional summit

June 30, 2016

Members from North Carolina’s three National Cancer Institute-designated comprehensive cancer centers, together with care providers, researchers, advocates and patients from the state, met in Chapel Hill to be part of a national discussion on how to speed the pace of cancer discovery and clinical advances.

Carey to co-chair national breast cancer clinical trials group

June 1, 2016

UNC Lineberger member Lisa A. Carey, MD, has been appointed co-chair of the Alliance for Clinical Trials in Oncology Breast Committee. The national organization is responsible for developing new trials, ensuring each project’s scientific excellence, operational efficiency and productivity, and promoting collaboration with other NCI-funded clinical trials groups.

Menopausal status may be more important than age in breast cancer screening frequency, study finds

October 28, 2015

A study published in JAMA Oncology found that pre-menopausal women who were diagnosed with breast cancer following a biennial screening mammogram were likely to have more advanced tumors than woman screened annually. UNC Lineberger researcher Louise Henderson was a co-author on the study, which was co-led by researchers at the University of California-Davis School of Medicine and the Dana-Farber Cancer Institute.