Cancer Cell Biology Research Program Archives - Page 6 of 7

UNC Lineberger’s Greg Wang, PhD, has been honored as one of four recipients of this year’s Phillip and Ruth Hettleman Prizes for Artistic and Scholarly Achievement. The late Phillip Hettleman, a member of the UNC-Chapel Hill class of 1921, and his wife, Ruth, established the prestigious award in 1986 to recognize the achievements of outstanding junior faculty. The recipients …

E-cigarette usage may impair fertility and pregnancy outcomes, according to a study Kathleen Caron, PhD, and colleagues published in the Journal of the Endocrine Society.

E-cigarette “vaping” is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers with emphysema. In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC scientists found that the lungs of vapers …

The idea was simple: find the faulty signals that drive cancerous growth in cells, and block them. But what University of North Carolina Lineberger Comprehensive Cancer Center researcher Pengda Liu, PhD, has discovered, when it comes to cancer, even straightforward concepts can become complicated. “When you find a target and inhibit it, you find the …

Basal-like breast cancer is the most aggressive and difficult-to-treat subtype of breast cancer, and it largely overlaps with the triple-negative classification of the disease. Patients are in dire need of improved therapies that attack the underlying cellular features of these types of breast cancer. Now scientists at the University of North Carolina Lineberger Comprehensive Cancer …

UNC Lineberger awarded grants to 14 scientists and research teams in the fall grant awards cycle. Applications for the next round of funding will be due March 15.

Megan Agajanian, Alison Axtman, M. Ben Major, PhD

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have discovered how a cellular signal that’s abnormally hyperactive in cancer can be deactivated. In the journal Cell Reports, UNC Lineberger’s M. Ben Major, PhD, and colleagues published a paper on how the WNT signaling pathway is regulated. WNT proteins increase tumor onset, growth …

University of North Carolina Lineberger Comprehensive Cancer Center scientist Antonio “Tony” Amelio, PhD, is not necessarily looking for the “smoking gun” of cancer biology, or one single cause of cancer. Instead, he’s looking into how a family of newly described proteins involved in the cellular stress response can cause a complex ripple effect of changes …

H. Shelton Earp, MD, and G. Greg Wang, PhD, have published a study that describe the role of androgen receptor variant 7 (AR-V7), an alternative form of the androgen receptor, that plays a key role in prostate cancer development.

In the journal Molecular Cell, researchers led by UNC Lineberger's G. Greg Wang, PhD, and H. Shelton Earp, MD, describe the role of a protein variant called androgen receptor variant 7 (AR-V7), which is an alternative form of the androgen receptor that plays a key role in prostate cancer development and treatment.

Tag: Cancer Cell Biology Research Program

Wang honored as one of four recipients of Phillip and Ruth Hettleman Prizes for Artistic and Scholarly Achievement

Vaping may harm fertility in young women

HealthDay News: Vaping May Trigger Lung Damage Like That Seen in Emphysema

E-cigs can trigger same lung changes seen in smokers, emphysema

Study provides insights behind hyperactivation of key cell proliferation signal

Scientists discover key enzyme in breast cancer proliferation, treatment resistance

UNC Lineberger awards $1.35M for cancer research

Scientists uncover mechanism cells use to deactivate a signal that’s hyperactive in cancer

Researchers publish milestone review on the role of cell signaling proteins in cancer

Insights about prostate cancer resistance could lead to treatment strategies