February 11, 2019
UNC Lineberger awards $1.35M for cancer research
UNC Lineberger awarded grants to 14 scientists and research teams in the fall grant awards cycle. Applications for the next round of funding will be due March 15.
Tag: Cancer Cell Biology Research Program
January 31, 2019
Scientists uncover mechanism cells use to deactivate a signal that’s hyperactive in cancer
University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have discovered how a cellular signal that’s abnormally hyperactive in cancer can be deactivated. In the journal Cell Reports, UNC Lineberger’s M. Ben Major, PhD, and colleagues published a paper on how the WNT signaling pathway is regulated. WNT proteins increase tumor onset, growth …
January 29, 2019
Researchers publish milestone review on the role of cell signaling proteins in cancer
University of North Carolina Lineberger Comprehensive Cancer Center scientist Antonio “Tony” Amelio, PhD, is not necessarily looking for the “smoking gun” of cancer biology, or one single cause of cancer. Instead, he’s looking into how a family of newly described proteins involved in the cellular stress response can cause a complex ripple effect of changes …
October 5, 2018
Insights about prostate cancer resistance could lead to treatment strategies
In the journal Molecular Cell, researchers led by UNC Lineberger's G. Greg Wang, PhD, and H. Shelton Earp, MD, describe the role of a protein variant called androgen receptor variant 7 (AR-V7), which is an alternative form of the androgen receptor that plays a key role in prostate cancer development and treatment.
July 19, 2018
Discovery of kidney cancer driver could lead to new treatment strategy
In a study published in the journal Science, researchers led by UNC Lineberger's Qing Zhang, PhD, suggest that ZHX2 is a potential new therapeutic target for clear cell renal cell carcinoma, which is the most common type of kidney cancer.