Scientists use ‘biological flashlight’ to control cell function

January 24, 2020

Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center can illuminate cells from within using an embedded “biological flashlight,” and then use the light to control the cell’s function. In a proof-of-concept study published in the journal ACS Synthetic Biology, researchers describe an advance in “optogenetics,” a field in which scientists use light … Continued

Researchers find clues to drug resistance in medulloblastoma subtype

January 13, 2020

University of North Carolina Lineberger Comprehensive Cancer Center researchers have new evidence to explain how drug resistance develops in a major subtype of medulloblastoma, the most common invasive brain tumor in children. A UNC Lineberger team led by Timothy Gershon, MD, PhD and Kirk Wilhelmsen MD, PhD, reported in the journal Nature Communications that they … Continued

Der named AAAS Fellow

November 26, 2019

The American Association for the Advancement of Science has named Channing Der, PhD, the Sarah Graham Kenan Distinguished Professor of Pharmacology and member of the UNC Lineberger Comprehensive Cancer Center, as an AAAS Fellow. The honor recognizes Der’s “distinguished contributions to the field of cancer research through the discovery of RAS in cancer and the … Continued

Feast or famine: Scientists find key bio ‘switch’ that helps cells adapt

November 5, 2019

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments. In a study published in Molecular Cell, the scientists found that a chemical mark on histones – a key protein involved in the function of our … Continued

Researchers use genetic insights to develop model for HPV-linked head and neck cancer

November 5, 2019

A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different … Continued