Researchers find clues to drug resistance in medulloblastoma subtype

January 13, 2020

University of North Carolina Lineberger Comprehensive Cancer Center researchers have new evidence to explain how drug resistance develops in a major subtype of medulloblastoma, the most common invasive brain tumor in children. A UNC Lineberger team led by Timothy Gershon, MD, PhD and Kirk Wilhelmsen MD, PhD, reported in the journal Nature Communications that they … Continued

Der named AAAS Fellow

November 26, 2019

The American Association for the Advancement of Science has named Channing Der, PhD, the Sarah Graham Kenan Distinguished Professor of Pharmacology and member of the UNC Lineberger Comprehensive Cancer Center, as an AAAS Fellow. The honor recognizes Der’s “distinguished contributions to the field of cancer research through the discovery of RAS in cancer and the … Continued

Feast or famine: Scientists find key bio ‘switch’ that helps cells adapt

November 5, 2019

Scientists from the UNC School of Medicine and Stanford University have uncovered what may be a fundamental biological mechanism that helps organisms adapt to rapid changes to nutrients in their environments. In a study published in Molecular Cell, the scientists found that a chemical mark on histones – a key protein involved in the function of our … Continued

Researchers use genetic insights to develop model for HPV-linked head and neck cancer

November 5, 2019

A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different … Continued

Researchers identify possible approach to block medulloblastoma growth

October 23, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children. UNC Lineberger’s Timothy Gershon, MD, PhD and colleagues reported in the journal Development that by blocking a signal called GSK-3, they could control tumor growth in a … Continued

Legant Named 2019 Packard Fellow

October 21, 2019

UNC Lineberger’s Wesley Legant, PhD, assistant professor in the UNC-NC State Joint Department of Biomedical Engineering and the Department of Pharmacology, received a prestigious Packard Fellowship to enhance his research on new kinds of microscopy techniques to further biomedical discoveries at the UNC School of Medicine and beyond. Legant was one of 22 early-career scientists … Continued

Wang honored as one of four recipients of Phillip and Ruth Hettleman Prizes for Artistic and Scholarly Achievement

September 23, 2019

UNC Lineberger’s Greg Wang, PhD, has been honored as one of four recipients of this year’s Phillip and Ruth Hettleman Prizes for Artistic and Scholarly Achievement. The late Phillip Hettleman, a member of the UNC-Chapel Hill class of 1921, and his wife, Ruth, established the prestigious award in 1986 to recognize the achievements of outstanding junior faculty. The recipients … Continued

Vaping may harm fertility in young women

September 6, 2019

E-cigarette usage may impair fertility and pregnancy outcomes, according to a study Kathleen Caron, PhD, and colleagues published in the Journal of the Endocrine Society.