July 27, 2016
When Beth Silverstein tested positive for the BRCA1 gene mutation, she knew she had to make some tough decisions about her health. But she wasn't alone. Her faith, her family and her multi-disciplinary health care team at UNC Lineberger were with her every step of the way.
October 8, 2015
UNC Lineberger Comprehensive Cancer Center researchers helped lead an effort by The Cancer Genome Atlas Network of researchers to map the genetic drivers of invasive lobular carcinoma, the second most commonly diagnosed invasive form of breast cancer. They found that this cancer type may be at least three different diseases that differ in their microenvironmental features and outcomes.
September 22, 2015
UNC Lineberger Comprehensive Cancer Center researchers and eight other leading cancer research institutions have won a five-year, $12 million grant to try to find treatments for a group of cancers linked to mutations in the NF1 gene.
September 21, 2015
Researchers from Norway visited UNC Lineberger Comprehensive Cancer Center to learn firsthand about UNCseq, a clinical trial launched in 2011 at the N.C. Cancer Hospital. In the trial, researchers use a profile of the genetic and molecular alterations in patients' tumors to try to identify targeted treatments for them.
September 7, 2015
A UNC Lineberger-led study, published today in Nature Genetics, paves the way for potential personalized medicine approaches for the deadly cancer type.
June 10, 2015
UNC Lineberger will be enrolling patients into a new, national clinical trial, known as NCI-MATCH, that will group patients based on the genetics of their tumors as opposed to where their cancer is located. The new initiative will test more than 20 drugs or drug combinations targeting specific genetic mutations.
May 27, 2015
UNC Lineberger researchers are collaborating through the ClinGen consortium - a program launched to evaluate the clinical relevance of genetic variants - to help physicians make predictions about an individual’s risk of disease, develop more accurate clinical trials and design individualized treatments and care for patients.
May 5, 2015
UNC Lineberger will be one of more than a dozen leading cancer centers tapping IBM's Watson to accelerate DNA analysis and inform personalized treatment options for patients. The project is part of IBM’s broader Watson Health initiative to advance patient-centered care and improve health.
May 1, 2015
The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.
April 20, 2015
A cancer genomics study led by UNC Lineberger researchers and other scientists involved in The Cancer Genome Atlas (TCGA) project, a National Cancer Institute and National Human Genome Research Institute-backed effort to create a comprehensive atlas of the genetic changes in cancer, was selected as one of the top 10 clinical research achievements of the year. The project characterized molecular changes in 12 different cancers and revealed a new approach to classifying cancers.
