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Andrew Olshan, PhD, Professor and Associate Director for Population Sciences at UNC Lineberger Comprehensive Cancer Center

June 17, 2015

Early menarche may be important in development of aggressive breast cancer in African-American women

A multicenter research team known as the African American Breast Cancer Epidemiology and Risk Consortium (AMBER), which includes UNC Lineberger's Andrew Olshan, PhD has uncovered differences in ER-positive & ER-negative breast cancer pathways. The team examined whether relationships between age at menarche and breast cancer are the same for tumors that are ER-positive or ER-negative, particularly among African-American women. ER-negative breast cancer is generally more aggressive and known to be associated with a poorer prognosis than ER-positive disease.