April 23, 2021
Scientists make donation when cancer hits close to home
Barbara Savoldo, MD, PhD, and Gianpietro Dotti, MD, have established a fund to develop a CAR-T therapy for glioblastoma in honor of Savoldo's sister, Sonia.
Tag: CAR-T
March 4, 2021
Engineered safety switch curbs severe side effects of CAR-T immunotherapy
As part of a study led by Matthew Foster, MD, the advance was seen in a patient enrolled in a clinical trial using CAR-T to treat refractory acute B-cell leukemia.
January 25, 2021
European Medicines Agency awards priority designation for Hodgkin lymphoma CAR-T therapy
The European Medicines Agency granted priority medicines designation to Tessa Therapeutics’ CD30 targeted CAR-T therapy for patients with relapsed or refractory Hodgkin lymphoma.
January 6, 2021
Pharmacy Times: Study Suggests Way to Boost Immunotherapy Against Breast Cancer, Other Solid Tumors
January 4, 2021
Fierce Biotech: Research Putting the ‘STING’ on CAR-T cells to turn them against breast cancer and other solid tumors
January 4, 2021
Drug Target Review: Activating STING enhances CAR T-cell activity in solid tumours, shows study
December 31, 2020
United Press International: Study: Modified immunotherapy may work in advanced breast cancer
December 31, 2020
Study points the way to boosting immunotherapy effectiveness against breast cancer and other solid tumors
CAR-T therapy has proven effective for some blood cancers. New research by Jonathan S. Serody, MD, and colleagues suggests ways to use it effectively to attack solid tumors.
November 10, 2020
NCI Cancer Currents: For Childhood Eye Cancer, Researchers Investigating “Packaged” CAR T Cells
October 12, 2020
Therapy using immune system cells preserves vision in mice implanted with rare eye cancer
Zongchao Han, MD, PhD, Barbara Savoldo, MD, PhD, and colleagues report in Nature Cancer they used a combination of CAR-Ts and interleukin (IL)-15 to treat retinoblastoma in a mouse model.