CAR-T therapy gives patient options after cancer returns
February 13, 2020
When traditional cancer treatment options failed, Sabrina Shelton’s care team referred her to UNC for a CAR-T therapy clinical trial.
Tag: Cellular Immunotherapy
UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells
January 30, 2020
A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects. In a study published in Cancer Cell, researchers led by UNC Lineberger’s Gianpietro Dotti, … Continued
UNC Lineberger researchers to share data, expertise at 61st ASH Annual Meeting
December 6, 2019
University of North Carolina Lineberger Comprehensive Cancer Center researchers will be well-represented at the 61st American Society of Hematology Annual Meeting in Orlando, Florida, Dec. 7-10. ASH is the world’s largest professional society of hematologists and is dedicated to understanding, diagnosing, treating and preventing blood disorders. The society expects more than 20,000 hematologists and health … Continued
UNC Lineberger designs, develops and delivers CAR-T therapy to attack cancers
May 20, 2019
Jonathan Serody, MD, explains in a two-minute video the action behind chimeric antigen T-cell, or CAR-T, immunotherapy and how UNC Lineberger is designing, developing and delivering CAR-T therapies to treat cancers that fail to respond to standard treatments.
Stand Up To Cancer names UNC Lineberger researchers to ‘Dream Team’
January 30, 2019
The multi-institutional team, which is co-led by UNC Lineberger’s Gianpietro Dotti, MD, and includes six UNC Lineberger researchers, will focus on developing chimeric antigen receptor T-cell (CAR-T) therapies to recognize and attack T-cell lymphoma, a group of rare cancers of the blood and immune system.
Researchers identify molecular target for brain cancer, develop immunotherapy approach to attack it
February 28, 2018
A team led by UNC Lineberger’s Gianpietro Dotti, MD, has engineered immune cells to hunt glioblastoma, the most lethal primary brain tumor. They presented their findings in Science Translational Medicine.
UNC Lineberger receives $4 million gift to support promising new cancer treatment
April 10, 2017
Seeking to help in the development of treatments for metastatic cancer, Alice Lehman of Charlotte has donated $4 million to further the work of UNC Lineberger’s new cellular immunotherapy research program.