September 27, 2021
January 18, 2017
Study: Pro-inflammatory stress response promotes chemotherapy side effects and cancer relapse
A team of researchers, including UNC Lineberger's Norman E. Sharpless, MD, has shown that chemotherapy triggers a pro-inflammatory stress response termed cellular senescence, promoting the adverse effects of chemotherapy as well as cancer relapse and metastasis. Eliminating the senescent cells in mice prevented the side effects and relapse.
August 18, 2015
Wang published in ACS Nano
UNC Lineberger member Andrew Wang, MD, was senior author of a preclinical study published in the journal ACS Nano. Wang and collaborators found that they could improve cancer chemotherapy and chemoradiotherapy treatments by delivering a combination of cancer-fighting drugs using nanoparticles.
February 12, 2015
Sleep for Cells
With new funding, a UNC startup is poised to halt the most devastating effects of chemotherapy.
February 4, 2015
Potential pancreatic cancer treatment could increase life expectancy
Device that drives drugs into solid tumors that are poorly vascularized opens the possibility of life-saving surgeries in cancer patients.
December 3, 2014
UNC researchers pinpoint chemo effect on brain cells
UNC Lineberger members and UNC School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of “chemo brain” – the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble concentrating that many cancer patients experience while on chemotherapy to treat tumors in other parts of the body.
March 28, 2014
UNC researchers show cancer chemotherapy accelerates ‘molecular aging’
Physicians have long suspected that chemotherapy can accelerate the aging process in patients treated for cancer. Using a test developed at UNC Lineberger Comprehensive Cancer Center to determine molecular aging, UNC oncologists have directly measured the impact of anti-cancer chemotherapy drugs on biological aging.
March 5, 2014
Endeavors – Chasing Pac-Man
Two UNC researchers design a biological test to individualize chemotherapy.
February 6, 2014
NIH grant to improve efficiency of chemotherapy drugs
A team led by Cyrus Vaziri, PhD, and William Janzen at the University of North Carolina at Chapel Hill has received a grant from the National Institutes of Health for research that could help make chemotherapy drugs more effective.
December 16, 2013
Combined therapy reduces recurrence in women with small, HER2+ breast cancers
A new study shows combined therapy is linked to a lower chance of recurrence in women with small, HER2+ breast cancers.