Clinical Immunotherapy Program Archives - UNC Lineberger Comprehensive Cancer Center

August 10, 2026

WCHL: UNC’s Comprehensive Cancer Center Receives $20 Million Donation to Expand Research

Drs. Barbara Savoldo, Gianpietro Dotti, Robert L. Ferris, Natalie Grover and Jonathan S. Serody at the UNC Health Foundation’s Game Changers event on November 4, 2025

This gift will fuel the next generation of cancer treatments, supporting all aspects of the UNC Lineberger Cellular Immunotherapy Program with an emphasis on clinical trials, expansion of the cellular therapeutics facility, and faculty recruitment and retention.

Human cells with acute myelocytic leukemia (AML) in the pericardial fluid, shown with an esterase stain at 400x magnification.

Gianpietro Dotti, MD, Paul Armistead, MD, PhD, and colleagues have created a new cellular immunotherapy that targets acute myeloid leukemia (AML) cells without impacting normal blood production, which is one of the major challenges associated with AML treatment.

A person wearing head-to-toe medical protective garments at a hooded work station in the Advanced Cellular Therapeutics Facility. They are pipetting into a container.

The Foundation for the Accreditation of Cellular Therapy awarded accreditation without any deficiency citations to UNC Lineberger’s Advanced Cellular Therapeutics Facility.

Scientific illustration of a CAR-T cell attacking a cancer cell.

Gianpietro Dotti, MD, and colleagues report in Nature Immunology they have identified a cocktail of three different drugs that can be used to generate more robust CAR-Ts to fight cancer.

Headshots of Jonathan Serody and Jen Jen Yeh.

Jonathan Serody, MD, and Jen Jen Yeh, MD, were named the 2023 recipients of the Hyman L. Battle Distinguished Cancer Research Award, recognizing their significant scientific achievements.

Jonathan Serody, MD, Ian Davis, MD, PhD, and colleagues report ILC2s can change functions after a patient receives stem cells, thereby preventing a healthy rebuilding of the immune system.

A person wearing PPE looking into a microscope.

UNC Lineberger researchers are using CAR-T to create better and personalized cancer treatments in one of the largest cell therapy facilities on the East Coast.

Speakers of the inaugural Shea Symposium

The inaugural symposium featured talks on adoptive cellular therapy for lymphoid malignancies and novel approaches for the treatment of acute myeloid leukemia, myelodysplastic syndromes and myeloproliferative neoplasms.

Tag: Clinical Immunotherapy Program

WCHL: UNC’s Comprehensive Cancer Center Receives $20 Million Donation to Expand Research

Transformational $20 million commitment will support UNC Lineberger’s Cellular Immunotherapy Program

UNC researchers create more effective, less toxic immunotherapy to combat blood cancer

UNC Lineberger’s Advanced Cellular Therapeutics Facility earns accreditation

Three drug cocktail shows potential to boost CAR-T cancer therapy

Serody and Yeh honored with Battle Distinguished Cancer Research Award

Immune cell transformation can influence stem cell transplant success in cancer patients

Ivanhoe Broadcast News: Brain Cancer: Targeted by Immunotherapy

Curated cancer care

Thomas C. Shea Clinical Cancer Symposium brings together national leaders in blood cancers