February 13, 2020
CAR-T therapy gives patient options after cancer returns
When traditional cancer treatment options failed, Sabrina Shelton's care team referred her to UNC for a CAR-T therapy clinical trial.
Tag: clinical trials
January 30, 2020
UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells
A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects. In a study published in Cancer Cell, researchers led by UNC Lineberger’s Gianpietro Dotti, …
August 18, 2015
Working wonders
UNC Lineberger member Frances Collichio, MD, was an investigator for a clinical trial for a treatment that uses a modified virus against melanoma. The treatment meant remission for Willis Davis, who had been diagnosed with stage IIIc melanoma in 2009.
August 13, 2015
Landmark study validates method for patient reporting of cancer drug-related adverse events
In an article published in JAMA Oncology today, a study led by UNC Lineberger's Ethan Basch and colleagues shows that a system they developed accurately and reliably captures the patient experience with cancer drug side effects.
June 10, 2015
Precision medicine at UNC: Looking for cancer-driving gene mutations across cancers
UNC Lineberger will be enrolling patients into a new, national clinical trial, known as NCI-MATCH, that will group patients based on the genetics of their tumors as opposed to where their cancer is located. The new initiative will test more than 20 drugs or drug combinations targeting specific genetic mutations.
May 27, 2015
UNC Lineberger member to lead NCI grant to improve clinical trials for cancer patients
UNC Lineberger member Michael R. Kosorok, PhD, W.R. Kenan Jr. Distinguished Professor and chair of biostatistics at UNC’s Gillings School of Global Public Health, is the contact principal investigator for an multi-institution effort to continue to find ways to develop more powerful clinical trials for cancer patients. The project is backed by a five-year, $10.4 million grant from the National Cancer Institute.
April 12, 2015
UNC Lineberger members to share research, expertise at 2015 AACR meeting
UNC Lineberger Comprehensive Cancer Center researchers will share their study findings and expertise at the American Association for Cancer Research’s annual meeting, which is expected to draw thousands to Philadelphia April 18-22 to discuss advances in cancer science.
March 30, 2015
UNC Lineberger-led study tests drug strategy for aggressive breast cancer in the brain
Results from a UNC Lineberger-led study were published Monday in the journal Molecular Cancer Therapeutics. The pre-clinical study was the first to investigate one particular drug strategy as a treatment for breast cancer after it's spread to the brain.
March 3, 2015
UNC Lineberger’s Muss honored as exemplary cancer caregiver
The American Cancer Society has honored Hyman B. Muss, MD, director of the UNC Lineberger Comprehensive Cancer Center Geriatric Oncology Program, with a prestigious national award that recognizes providers who show compassion and dedication beyond the call of duty.
February 5, 2015
UNC-Chapel Hill spinout secures $33 million investment to advance novel cancer treatments
One of nation’s top universities yields more than 150 startup companies to date, including G1 Therapeutics, creating jobs and advancing innovation and entrepreneurship.