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Precision oncology insights revealed for colorectal cancer

March 19, 2019

Next-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to different survival and treatment outcomes in an analysis led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher. The findings, published in the Journal of Clinical Oncology, could help define strategies to more effectively treat colorectal … Continued

Study by UNC Lineberger scientist details role of tumor suppressor

October 15, 2015

UNC Lineberger Comprehensive Cancer Center researchers are working to better understand the cell-to-cell signaling that can cause precancerous polyps in the colon when signaling goes awry. In a study published in the open-access journal eLife, they describe the role of a key tumor suppressor protein called APC in helping to keep cells in the colon crypts from growing out of control.