UNC Lineberger researchers led by Yuliya Pylayeva-Gupta, PhD, have identified the culprit that keeps cancer-killing immune cells from reaching pancreatic cancer tumors.
Tumors can create a hostile environment for cancer-fighting immune cells. In a new study, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method for engineering immune cells to improve their survival and proliferation, even within a hostile tumor. Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, report in the journal Nature … Continued
A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects. In a study published in Cancer Cell, researchers led by UNC Lineberger’s Gianpietro Dotti, … Continued
Yuliya Pylayeva-Gupta, PhD, and Gaorav Gupta, MD, PhD, use their natural curiosity and drive to tackle cancer through their research at UNC Lineberger.
The U.S. Army has awarded a $559,799 grant to University of North Carolina Lineberger Comprehensive Cancer Center researcher Yuliya Pylayeva-Gupta, PhD, to investigate the role of the immune system in promoting pancreatic cancer’s spread. Pancreatic cancer is the third leading cause of cancer death in the United States, and it is one of the deadliest … Continued
Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have designed and validated a model for predicting what might make an effective cancer vaccine against a patient’s tumor. This finding could help overcome a significant obstacle in the development of personalized cancer vaccines. In a study published in the journal Cancer Immunology Research, … Continued
Jenny P. Ting, PhD, the William Kenan Professor of Genetics and Microbiology & Immunology has been elected to serve as vice president of the American Association of Immunologists for the 2019-2020 term. Ting has been an active member of the organization for since 1997. AAI is dedicated to advancing the field of immunology and fostering … Continued
The National Cancer Institute has awarded a grant for more than $2.2 million across five years to UNC Lineberger’s Yuliya Pylayeva-Gupta, PhD, to support her research into the immune response in pancreatic cancer, one of the deadliest cancers. “Understanding the role of immune regulation in pancreatic cancer represents a crucial stepping stone on our way … Continued
University of North Carolina Lineberger Comprehensive Cancer Center researchers presented innovative new strategies for using tiny particles – particles the size of a DNA molecule or the width of a human hair – to boost cancer treatment as part of the Carolina Center of Cancer Nanotechnology Excellence/National Cancer Institute site visit on Tuesday. The researchers, … Continued
The University of North Carolina System recently awarded UNC Lineberger’s Andrew Wang, MD, and Jonathan Serody, MD, a four year, $2.09 million Research Opportunities Initiative grant to support their research using pharmacoengineering approaches to develop more effective personalized cancer vaccines. The grant was one of 15 awarded to scientists across the UNC System, with the specific intent to support … Continued