Neuro-oncology Clinical Program Archives

Shawn Hingtgen, PhD, and his lab team have developed a method they call a “slice platform” that may help clinicians choose the best treatment for their brain tumor patients.

David Hesmer is a volunteer in a UNC Lineberger lab, helping to further the study of glioblastoma, something he knows a lot about: he was treated for glioblastoma at the N.C. Cancer Hospital.

Shawn Hingtgen, PhD, said removing a glioblastoma causes any tumor cells that remained in the brain to grow at a much faster rate than the original tumor.

A study led by UNC Lineberger member Shawn Hingtgen, PhD, has determined that removing a glioblastoma tumor from the brain causes any cancer left behind to grow much faster than the original tumor did. The findings from the Neuro-Oncology paper illustrate the effect of surgery on the brain and tumor and the need to rethink how to treat the disease differently after the surgery.

Using a new ‘chemogenetic’ technique invented at UNC, scientists turn neurons ‘on’ and ‘off’ to demonstrate how brain circuits control behavior in mice. This unique tool – the first to result from the NIH BRAIN Initiative – will help scientists understand how to modulate neurons to more effectively treat diseases.

Tag: Neuro-oncology Clinical Program

Devising a smarter way to treat brain tumors

Grateful patient works with lab team to find cancer therapies

Removing a brain tumor makes remaining cancer more aggressive

A BRAIN Initiative first: new tool can switch behavior ‘on’ and ‘off’