Teaming up in the lab and in life: researchers make an impact on cancer science

January 16, 2020

From an early age, they were both fascinated by science; he was amazed by advances in genetic engineering, and she was learning everything she could about plants. Fast forward to today, and UNC Lineberger researchers Gaorav Gupta, MD, PhD, and Yuliya Pylayeva-Gupta, PhD, are using their natural curiosity and drive to tackle the problem of … Continued

Pancreatic cancer patient beats the odds to thrive after diagnosis

January 9, 2020

Mary Gillam never thought she’d be celebrating the Tar Heels winning the NCAA Men’s Basketball Championship from a hospital ER. Instead, while students partied joyfully outside, Gillam had to face a hard diagnosis — a mass on her pancreas that was later determined to be pancreatic cancer. “I thought to myself, ‘This has to be … Continued

Der named AAAS Fellow

November 26, 2019

The American Association for the Advancement of Science has named Channing Der, PhD, the Sarah Graham Kenan Distinguished Professor of Pharmacology and member of the UNC Lineberger Comprehensive Cancer Center, as an AAAS Fellow. The honor recognizes Der’s “distinguished contributions to the field of cancer research through the discovery of RAS in cancer and the … Continued

Pancreatic cancer tumor classification could optimize treatment choices

November 21, 2019

A study from the University of North Carolina Lineberger Comprehensive Cancer Center could help predict resistance to treatments for pancreatic cancer, one of the deadliest cancer types. In Clinical Cancer Research, a journal of the American Association for Cancer Research, researchers led by UNC Lineberger’s Jen Jen Yeh, MD, and Naim Rashid, PhD, reported findings … Continued

Researchers develop method for separating tissue types in tumor samples

October 21, 2019

A dense web of tissue can surround pancreatic cancer tumors, impeding treatment and sometimes acting as a barrier to the tumor’s spread. Researchers want to distinguish cancerous tissue from the surrounding connective tissue and cells known as stroma as well as from immune cells in the tumor’s environment in order to drive personalized treatment strategies. … Continued

Der leads study published in Science Signaling

August 13, 2019

UNC Lineberger’s Channing Der, PhD, Kenan Distinguished Professor in the UNC School of Medicine Department of Pharmacology, was corresponding author of a paper published in Science Signaling. The study identified a potential therapeutic target for patients with KRAS-mutant pancreatic ductal adenocarcinoma. Der and his colleagues described in the paper the use of a screening strategy … Continued