Pengda Liu Archives - UNC Lineberger Comprehensive Cancer Center

August 27, 2026

Health Medicine Network: How Biochemists discover new strategy to combat pediatric bone cancer

Pengda Liu, PhD, and colleagues are investigating a new way to tackle Ewing sarcoma, an aggressive and rare pediatric cancer that develops in the bones and soft tissues, while minimizing toxicity typically associated with chemotherapy.

Pengda Liu was presented a $40,000 check from the Strides for Sarcoma Foundation.

Pengda Liu, PhD, was awarded $40,000 from the Strides for Sarcoma Foundation to support his work developing novel antibody-drug conjugates to facilitate the clinical translation of new targeted therapies for Ewing sarcoma.

Headshots of Xiaodong Wang and Pengda Liu.

Xiaodong Wang, PhD, and Pengda Liu, PhD, were awarded a $3.8 million NCI grant to develop a promising targeted treatment for a rare and aggressive pediatric cancer.

Illustration of a cancer cell with a target highlighted over the cell.

UNC Eshelman School of Pharmacy’s Chemical Biology and Medicinal Chemistry Division is a central hub for cancer therapeutics. Its faculty members are studying the chemical and biological mechanisms that promote cancer growth and persistence.

A dermatologist examines the skin of a patient's arm with a dermatoscope.

Researchers found that inhibiting a problematic protein in the body helps immunotherapies and CAR-T therapy to better fight off melanoma.

Ewing's sarcoma that has metastasized to the pleura fluid.

Pengda Liu, PhD, and colleagues have created a small molecule that targets and breaks down a protein linked to Ewing sarcoma, an aggressive cancer that mostly affects children and teens.

AACR (American Association for Cancer Research) Annual Meeting 2025 Chicago.

Nearly 30 UNC Lineberger and UNC faculty and trainees will present findings and participate during the American Association for Cancer Research annual meeting in Chicago, April 25-30.

Pengda Liu, PhD, and colleagues have identified an unexpected biological function of 2’3’-cGAMP, one that can facilitate cell migration and how cancer spreads.

Tag: Pengda Liu

Health Medicine Network: How Biochemists discover new strategy to combat pediatric bone cancer

FirstWord Pharma: UNC Biochemists Discover New Method to Combat Pediatric Bone Cancer

UNC biochemists discover new method to combat pediatric bone cancer

Liu Lab receives Maia James Sarcoma Innovation Grant Award

Advancing new Ewing sarcoma therapy

Priming the pump for new cancer treatments

UNC researchers unlock new way to help fight skin cancer

Researchers develop molecule that targets Ewing sarcoma

UNC Lineberger and UNC faculty and trainees present findings at AACR annual meeting

Researchers identify new protein pathway, biological function important for cell migration, cancer metastasis