Researchers develop method to engineer immune cells so they grow even in hostile tumors

February 3, 2020

Tumors can create a hostile environment for cancer-fighting immune cells. In a new study, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method for engineering immune cells to improve their survival and proliferation, even within a hostile tumor. Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, report in the journal Nature … Continued

UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells

January 30, 2020

A discovery by University of North Carolina Lineberger Comprehensive Cancer Center researchers could allow scientists to fine-tune genetically engineered immune cells to heighten their killing power against tumors or to decrease their activity level in the case of severe side effects. In a study published in Cancer Cell, researchers led by UNC Lineberger’s Gianpietro Dotti, … Continued

Scientists use ‘biological flashlight’ to control cell function

January 24, 2020

Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center can illuminate cells from within using an embedded “biological flashlight,” and then use the light to control the cell’s function. In a proof-of-concept study published in the journal ACS Synthetic Biology, researchers describe an advance in “optogenetics,” a field in which scientists use light … Continued

Comparing cancer costs is challenging, despite new price transparency rules

January 16, 2020

Comparison shopping for airfare, a TV, or a car can be straightforward online. The same cannot be said for checking what hospitals charge for a standard radiation treatment for prostate cancer, according to a report published in JAMA Oncology. Trevor Royce, MD, MPH, MS, of the University of North Carolina Lineberger Comprehensive Cancer Center, is … Continued

Prostate Cancer Foundation awards grant to Coombs

December 17, 2019

The Prostate Cancer Foundation has awarded $225,000 across three years to UNC Lineberger’s Catherine C. Coombs, MD, to study whether genetic mutations that accumulate in the blood over time are linked to worse outcomes for prostate cancer. Coombs, an assistant professor in the UNC School of Medicine Division of Hematology/Oncology, received the Young Investigator Award … Continued

Lung Cancer Initiative awards research grant to Du to investigate novel treatment

December 16, 2019

The Lung Cancer Initiative of North Carolina (LCI) has awarded The Vicky Amidon Innovation in Lung Cancer Research Award to Hongwei Du, PhD, a postdoctoral fellow at University of North Carolina School of Medicine and Lineberger Comprehensive Cancer Center. The award also was presented to Kenneth Adler, PhD, at the North Carolina State University College … Continued