April 28, 2016
A study, authored by UNC Lineberger member Stacie Dusetzina, PhD, found that oral cancer drugs introduced in 2014 were, on average, six times more expensive than those introduced in the year 2000. The findings, published in JAMA Oncology, raised concerns as patients may increasingly take on the cost burden of those increases.
April 20, 2016
Sequencing a tumor's RNA in addition to its DNA makes it possible to better characterize the cancer’s mutations, reported Neil Hayes, MD, MPH, at the American Association for Cancer Research’s annual meeting. This additional information, said Hayes, may help improve a cancer patient’s treatment.
April 18, 2016
A potential new blood test is sensitive enough to detect changes in numbers of head and neck cancer cells circulating in the blood, a pilot study by UNC Lineberger Comprehensive Cancer Center researchers and collaborators has found. The findings from the study will be presented at the American Association for Cancer Research Annual Meeting in New Orleans on Tuesday, April 19.
April 18, 2016
UNC Lineberger Comprehensive Cancer Center researchers have identified a combination of investigational drugs that have been shown to be effective together at targeting triple negative breast cancer in the brain in preclinical studies. Their findings will be presented at the American Association for Cancer Research Annual Meeting in New Orleans, Tuesday, April 19.
April 18, 2016
A study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and other institutions found a link between higher intake of dietary saturated fat, a type of fat found commonly in foods such as fatty beef and cheese, and risk of aggressive prostate cancer. The preliminary results were presented at the American Association for Cancer Research Annual Meeting in New Orleans on Monday, April 18.
April 17, 2016
More than 440 people recently attended the 40th Annnual UNC Lineberger Scientific Symposium, which featured talks on treatments and ongoing research that target the RAS-RAF-MEK-ERK and other signaling pathways in cancer.
April 5, 2016
Two UNC Lineberger Comprehensive Cancer Center members - Drs. Deborah Mayer and Barbara Rimer - have been honored with appointments to the National Cancer Moonshot Initiative's Blue Ribbon Panel. They will join a team of cancer experts to provide advice and vision in the implementation of the national program.
March 18, 2016
Researchers at UNC Lineberger and at other institutions developed a new potential treatment for acute myeloid leukemia. In the journal JCI Insight, they report that the compound MRX-2843 more than doubled the median days of survival in laboratory models with a drug-resistant form of the disease.
March 10, 2016
In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.
February 29, 2016
In a first-of-its-kind-study, researchers have discovered and applied a new screening technique capable of testing thousands of potential drug compounds to see if those compounds can reverse abnormal DNA unwinding in Ewing sarcoma, a bone and soft tissue cancer that’s most common in teens and young adults.
