Genomic analysis paves way for personalized treatment of invasive lobular carcinoma

October 8, 2015

UNC Lineberger Comprehensive Cancer Center researchers helped lead an effort by The Cancer Genome Atlas Network of researchers to map the genetic drivers of invasive lobular carcinoma, the second most commonly diagnosed invasive form of breast cancer. They found that this cancer type may be at least three different diseases that differ in their microenvironmental features and outcomes.

UNC Lineberger researchers help map genetic mutations in skin cancer

June 18, 2015

UNC Lineberger researchers significantly contributed to a better understanding of the genetic alterations found in cutaneous melanoma as part of a multi-institution, international effort of The Cancer Genome Atlas (TCGA). Researchers collected samples from 331 patients and used several molecular methodologies to complete the study, the largest of its kind to-date for cutaneous melanoma. The findings were published in the journal Cell.

Clinical Research Forum selects genomic analysis as top 10 research achievement

April 20, 2015

A cancer genomics study led by UNC Lineberger researchers and other scientists involved in The Cancer Genome Atlas (TCGA) project, a National Cancer Institute and National Human Genome Research Institute-backed effort to create a comprehensive atlas of the genetic changes in cancer, was selected as one of the top 10 clinical research achievements of the year. The project characterized molecular changes in 12 different cancers and revealed a new approach to classifying cancers.