July 22, 2019
Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer. They also developed an experimental therapeutic to block the signal and slow tumor growth. In the journal Proceedings of the National Academy of Sciences, the researchers reported they have identified a …
July 12, 2019
A new study led by UNC Lineberger’s Antonio “Tony” Amelio, PhD, and colleagues was published in the journal Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, and featured on the cover of the July issue. Amelio is an assistant professor in the UNC Adams School of Dentistry Division of Oral and Craniofacial Health Sciences. …
July 12, 2019
University of North Carolina Lineberger Comprehensive Cancer Center researchers have published a review of experimental cancer vaccines that identified areas of promise and challenges for the field. In the Nature Reviews Cancer, researchers outlined current research into targets for therapeutic cancer vaccines, an area of active investigation focused on boosting immune responses to cancer. “Generally, …
June 13, 2019
Using a new blood test that’s in development, University of North Carolina Lineberger Comprehensive Cancer Center researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection. Researchers believe the findings, published in the journal Clinical Cancer Research, could help identify those …
April 19, 2019
The idea was simple: find the faulty signals that drive cancerous growth in cells, and block them. But what University of North Carolina Lineberger Comprehensive Cancer Center researcher Pengda Liu, PhD, has discovered, when it comes to cancer, even straightforward concepts can become complicated. “When you find a target and inhibit it, you find the …
April 17, 2019
A study by University of North Carolina Lineberger Comprehensive Cancer Center researchers helps explain how tumors recruit blood vessels that provide fuel for their growth as well as an avenue for the tumors to spread. In the journal Oncogene, the researchers also reported they built on these findings to uncover a potential treatment strategy to …
March 12, 2019
Basal-like breast cancer is the most aggressive and difficult-to-treat subtype of breast cancer, and it largely overlaps with the triple-negative classification of the disease. Patients are in dire need of improved therapies that attack the underlying cellular features of these types of breast cancer. Now scientists at the University of North Carolina Lineberger Comprehensive Cancer …
February 28, 2019
A pair of studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers could aid in improved diagnosis for melanoma, the deadliest form of skin cancer. The studies, led by UNC Lineberger’s Nancy Thomas, MD, PhD, Irene & Robert Alan Briggaman Distinguished Professor and Chair in the UNC School of Medicine Department of …
February 18, 2019
University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered county-level factors linked to higher colorectal cancer mortality rates in a cluster of counties in northeastern North Carolina. In the journal Cancer Epidemiology, researchers report 10 counties in northeastern North Carolina are part of a cluster of counties with higher rates of colorectal cancer …
February 11, 2019
UNC Lineberger awarded grants to 14 scientists and research teams in the fall grant awards cycle. Applications for the next round of funding will be due March 15.