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Charles M. Perou, PhD, Faculty Director
Jason Merker, MD, PhD, Faculty Director
Adam Pfefferle, PhD, Director


The UNC Lineberger Comprehensive Cancer Center Translational Genomics Lab (TGL) is a medium throughput facility providing comprehensive genomic services for investigators by employing Next Generation Sequencing (NGS) and NanoStringTM technologies. In addition, TGL can produce single-cell gene expression libraries using the 10X platform. The mission of TGL is to support translational human cancer genomics research at the University of North Carolina – Chapel Hill. The TGL facility performs sample processing and analyses for the molecular, pathologic, and genomic characterization of patient-derived specimens in preclinical research projects and clinical protocols. Our laboratory employs highly-automated, as well as manual, platforms for reproducible medium-throughput nucleic acid extraction, library preparation, and next-generation sequencing of tissue, cells, and blood samples. Our goal is to provide a resource that balances rigor and flexibility to meet the needs of academic and clinical research, and that can ultimately produce optimized and validated processes for adoption in clinical labs.


Kay Chao, Development Technologist
Stacey Donelan, Research Specialist
Xiaoyan Luo, Research Specialist
Julia Anne Portocarrero, Research Specialist
Tulay Yilmaz-Swenson, Research Specialist


Adam Pfefferle, PhD, Facility Director —

TGL partners with the UNC Lineberger Office of Genomics Research (OGR) for project management support. For a project consultation, email


5119 Marsico Hall
University of North Carolina – Chapel Hill


Monday – Friday
8 a.m. – 4 p.m.