Yeh Lab
Located within the UNC Lineberger Comprehensive Cancer Center, the Yeh Lab’s focus is to identify and study novel therapeutic targets for the treatment of pancreatic cancer. Pancreatic cancer in particular continues to be a lethal disease with few therapeutic options. Our research therefore centers on target identification through genomic, and more recently proteomic analyses of patient samples.
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Research
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Jen Jen Yeh named Smithies Investigator
The UNC School of Medicine has selected Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, and joint professor of pharmacology, for one of two annual awards in honor of Oliver Smithies, UNC’s first Nobel Prize winner.
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Narrowing the gap toward precision medicine for pancreatic cancer
To improve treatment and our understanding of one of the deadliest cancers in the United States, UNC Lineberger’s Jen Jen Yeh, MD, was involved in two studies that take different approaches to precision medicine for pancreatic cancer.
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Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
Richard Moffitt, a post-doctoral fellow in our group and now a tenure-track assistant professor at SUNY Stonybrook, led the mRNA and integrative analysis for the TCGA PAAD (pancreatic cancer) working group. The TCGA PAAD team performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic ductal adenocarcinoma specimens, including samples with characteristic low neoplastic cellularity. … Continued
