Other Cancers
Integrated single-dose kinome profiling data is predictive of cancer cell line sensitivity to kinase inhibitors – PubMed (nih.gov) PeerJ. 2023 Nov 16;11:e16342. doi: 10.7717/peerj.16342. eCollection 2023.
Joisa CU, Chen KA, Berginski ME, Golitz BT, Jenner MR, Herrera Loeza G, Yeh JJ, Gomez SM
Sub-Cluster Identification through Semi-Supervised Optimization of Rare-Cell Silhouettes (SCISSORS) in single-cell RNA-sequencing. Bioinformatics. 2023 Aug 1;39(8):btad449. doi: 10.1093/bioinformatics/btad449.
Promise of bile circulating tumor DNA in biliary tract cancers. Cancer. 2023 Jun 1;129(11):1643-1645. doi: 10.1002/cncr.34715. Epub 2023 Mar 18.
Kearney JF, Weighill D, Yeh JJ.
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth. Cancer Res. 2022 Jan 1;82(1):90-104. doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 4.
Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ.
Pathway and network analysis of more than 2500 whole cancer genomes. Nat Commun. 2020 Feb 5;11(1):729. doi: 10.1038/s41467-020-14367-0. PubMed PMID: 32024854; PubMed Central PMCID: PMC7002574.
Pan-cancer analysis of whole genomes. Nature. 2020 Feb;578(7793):82-93. doi: 10.1038/s41586-020-1969-6. Epub 2020 Feb 5. PubMed PMID: 32025007; PubMed Central PMCID: PMC7025898.
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature. 2020 Feb;578(7793):102-111. doi: 10.1038/s41586-020-1965-x. Epub 2020 Feb 5. PubMed PMID: 32025015; PubMed Central PMCID: PMC7054214.
MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma. Bailey ST, Smith AM, Kardos J, Wobker SE, Wilson HL, Krishnan B, Saito R, Lee HJ, Zhang J, Eaton SC, Williams LA, Manocha U, Peters DJ, Pan X, Carroll TJ, Felsher DW, Walter V, Zhang Q, Parker JS, Yeh JJ, Moffitt RA, Leung JY, Kim WY. Nat Commun. 2017 Jun 8;8:15770. doi: 10.1038/ncomms15770.
N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration. Rigoutsos I, Lee SK, Nam SY, Anfossi S, Pasculli B, Pichler M, Jing Y, Rodriguez-Aguayo C, Telonis AG, Rossi S, Ivan C, Catela Ivkovic T, Fabris L, Clark PM, Ling H, Shimizu M, Redis RS, Shah MY, Zhang X, Okugawa Y, Jung EJ, Tsirigos A, Huang L, Ferdin J, Gafà R, Spizzo R, Nicoloso MS, Paranjape AN, Shariati M, Tiron A, Yeh JJ, Teruel-Montoya R, Xiao L, Melo SA, Menter D, Jiang ZQ, Flores ER, Negrini M, Goel A, Bar-Eli M, Mani SA, Liu CG, Lopez-Berestein G, Berindan-Neagoe I, Esteller M, Kopetz S, Lanza G, Calin GA. Genome Biol. 2017 May 24;18(1):98. doi: 10.1186/s13059-017-1224-0.
Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MC, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Bertherat J, Fassnacht M, Wheeler DA; Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RG. Cancer Cell. 2016 Aug 8;30(2):363. doi: 10.1016/j.ccell.2016.07.013. Epub 2016 Aug 8. No abstract available.
Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain. Allali I, Delgado S, Marron PI, Astudillo A, Yeh JJ, Ghazal H, Amzazi S, Keku T, Azcarate-Peril MA. Gut Microbes. 2015;6(3):161-72. doi: 10.1080/19490976.2015.1039223. PMID: 25875428
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs. Londin E, Loher P, Telonis AG, Quann K, Clark P, Jing Y, Hatzimichael E, Kirino Y, Honda S, Lally M, Ramratnam B, Comstock CE, Knudsen KE, Gomella L, Spaeth GL, Hark L, Katz LJ, Witkiewicz A, Rostami A, Jimenez SA, Hollingsworth MA, Yeh JJ, Shaw CA, McKenzie SE, Bray P, Nelson PT, Zupo S, Van Roosbroeck K, Keating MJ, Calin GA, Yeo C, Jimbo M, Cozzitorto J, Brody JR, Delgrosso K, Mattick JS, Fortina P, Rigoutsos I. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1106-15. doi: 10.1073/pnas.1420955112. Epub 2015 Feb 23. PMID: 25713380
mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma. Bailey ST, Zhou B, Damrauer JS, Krishnan B, Wilson HL, Smith AM, Li M, Yeh JJ, Kim WY. PLoS One. 2014 Sep 2;9(9):e104413. doi: 10.1371/journal.pone.0104413. eCollection 2014. PMID: 25180793
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology. Damrauer JS, Hoadley KA, Chism DD, Fan C, Tiganelli CJ, Wobker SE, Yeh JJ, Milowsky MI, Iyer G, Parker JS, Kim WY. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3110-5. doi: 10.1073/pnas.1318376111. Epub 2014 Feb 11. PMID: 24520177
The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration. Cook DR, Solski PA, Bultman SJ, Kauselmann G, Schoor M, Kuehn R, Friedman LS, Cowley DO, Van Dyke T, Yeh JJ, Johnson L, Der CJ. Genes Cancer. 2011 Oct;2(10):932-42. doi: 10.1177/1947601912437035. PMID: 22701760
Phosphorylation by protein kinase Cα regulates RalB small GTPase protein activation, subcellular localization, and effector utilization. Martin TD, Mitin N, Cox AD, Yeh JJ, Der CJ. J Biol Chem. 2012 Apr 27;287(18):14827-36. doi: 10.1074/jbc.M112.344986. Epub 2012 Mar 5. PMID: 22393054
Differential gene expression between African American and European American colorectal cancer patients. Jovov B, Araujo-Perez F, Sigel CS, Stratford JK, McCoy AN, Yeh JJ, Keku T. PLoS One. 2012;7(1):e30168. doi: 10.1371/journal.pone.0030168. Epub 2012 Jan 19. PMID: 22276153
Activation and involvement of Ral GTPases in colorectal cancer. Martin TD, Samuel JC, Routh ED, Der CJ, Yeh JJ. Cancer Res. 2011 Jan 1;71(1):206-15. doi: 10.1158/0008-5472.CAN-10-1517. PMID: 21199803
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. Kim WY, Perera S, Zhou B, Carretero J, Yeh JJ, Heathcote SA, Jackson AL, Nikolinakos P, Ospina B, Naumov G, Brandstetter KA, Weigman VJ, Zaghlul S, Hayes DN, Padera RF, Heymach JV, Kung AL, Sharpless NE, Kaelin WG Jr, Wong KK. J Clin Invest. 2009 Aug;119(8):2160-70. PMID: 19662677
KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer. Yeh JJ, Routh ED, Rubinas T, Peacock J, Martin TD, Shen XJ, Sandler RS, Kim HJ, Keku TO, Der CJ. Mol Cancer Ther. 2009 Apr;8(4):834-43. doi: 10.1158/1535-7163.MCT-08-0972. PMID: 19372556