This course is designed for LCCC Training Grant Fellows and is led by Dr. Stephanie Montgomery, a board-certified veterinary pathologist and Faculty Director of the Animal Histopathology and Laboratory Medicine Core. Topics covered include best practices for necropsy techniques, tissue sampling & preservation, and tissue immunohistochemistry/immunofluorescence. Emphasis is placed on ensuring rigor & reproducibility in pathology. … Read more
This workshop, led by Bob Duronio and Brian Strahl, will highlight the power of smaller eukaryotes (e.g., yeast and flies) to uncover basic principles of cell biology, and thus, how discoveries made in these organisms have led the way in our understanding of disease pathways. We also will cover how model organisms have been a … Read more
The Models Systems II workshop will focus on the use of mice to model human cancer, discussing traditional xenograft studies, genetically engineered models, and patient-derived tumor xenografts (PDXs). We will discuss models of KRAS-driven cancer (pancreatic, lung); prostate cancer via the PTEN-deletion model; GBM models for low grade and high grade tumors; and models for … Read more
Led by Dirk Dittmer, registration will be required, details will be available closer to the date.
This workshop will focus on defining general aspects and approaches to drug discovery, the challenges and opportunities in academic drug discovery, and case histories of drug and probe discovery at UNC. Workshop leader: Stephen Frye Register: http://tinyurl.com/vsy6te9
This workshop, led by Dr. Dirk Dittmer, will be an overview of data science and statistical topics that may be of particular interest to basic science researchers. For example, when do I have to stop using Excel, — switch to R, and ask a real statistician. (1) Everyone, please bring a laptop with excel (2) Please send questions … Read more
Register Now for this Workshop Advancements in technology have led to a myriad of high dimensional genomic, genetic, and proteomic technologies now being applied to human tumors. Much of these data are now in public databases. This workshop focuses on how to find and use the data (TCGA, dbGaP, GEO, EGA, cBioPortal, among others), data … Read more
Proteomics (elective) - This workshop covers the basic principles, experimental design, and data analysis platforms for protein mass spectrometry experiments. Discussion topics include highlights of several upstream biochemical approaches, an overview of peptide fractionation by liquid chromatography, and the inner workings of ion trap mass spectrometers, including principles of ion detection and fragmentation. Lastly, the … Read more
This workshop focuses on defining general aspects and approaches to drug discovery, the challenges and opportunities in academic drug discovery, and case histories of drug and probe discovery at UNC. It is led by ITCMS preceptor Stephen Frye, Director of the Center for Integrative Chemical Biology and Drug Discovery, UNC Eshelman School of Pharmacy. He … Read more
This workshop highlights the power of smaller eukaryotes (e.g., yeast and flies) to uncover basic principles of cell biology, and thus, how discoveries made in these organisms have led the way in our understanding of disease pathways. We also cover how model organisms have been a powerful tool for drug discovery. ITCMS fellows are encouraged … Read more
