Mauro Calabrese, PhD, will be presenting at the bi-monthly CETP Colloquium for CETP trainees. His topic is “Long non-coding, micro and e-RNAs.” Dr. Calabrese is an Associate Professor the Director of Graduate Studies in the UNC-Chapel Hill Department of Pharmacology.
Jason Stein and Rob McGinty's labs will be presenting via Zoom.
DNA methylation (led by Dr. Ideraabdullah)- Alternations in DNA methylation constitute one of the best-known features of the cancer genome. Cancer-associated mutations in regulators of methylation such as IDH1 and cancers seemingly linked exclusively to alteration in DNA methylation point to the importance of these modifications. Dr. Ideraabdullah will review the discovery of DNA methylation … Read more
bioinformatics and statistical approaches to large data analysis (led by Dr. Furey)- The exploration of large datasets has become critical for many studies of the cancer epigenome. Although impossible to fully cover in a single colloquium, Dr. Furey will highlight the available approaches and resources to test large datasets with hypothesis-directed questions. He will also … Read more
mutations of epigenetic machinery in cancer (led by Dr. Wang)- Mutations in genes that regulate the epigenome occur commonly in a wide range of human cancers. Dr. Wang will survey the nature of the mutations that alter the activity of a broad range of chromatin regulators, (examples include EZH2, ATRX, SETD2) and their roles in … Read more