Pancreatic cancer tumor classification could optimize treatment choices

November 22, 2019

A study from the University of North Carolina Lineberger Comprehensive Cancer Center could help predict resistance to treatments for pancreatic cancer, one of the deadliest cancer types. In the journal Clinical Cancer Research, a journal of the American Association for Cancer Research, researchers led by UNC Lineberger’s Jen Jen Yeh, MD, and Naim Rashid, PhD, reported … Continued

Researchers develop method for separating tissue types in tumor samples

October 21, 2019

In the journal Nature Communications, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center reported they have designed a computational method for separating the different tissues in a particular sample – whether that is stroma in the case of pancreatic cancer, immune cells or cancer cells.

Matt Lipner successfully completes PhD defense

February 19, 2019

We are thrilled to congratulate Matthew Lipner of Yeh lab on successfully completing his PhD defense, an achievement that follows years of hard work. A successful PhD defense is one of the landmark achievements of a researcher’s career and is sure to be only the first step in Matt’s journey.

Jen Jen Yeh named Smithies Investigator

May 8, 2018

The UNC School of Medicine has selected Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, and joint professor of pharmacology, for one of two annual awards in honor of Oliver Smithies, UNC’s first Nobel Prize winner.

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

December 17, 2017

Richard Moffitt, a post-doctoral fellow in our group and now a tenure-track assistant professor at SUNY Stonybrook, led the mRNA and integrative analysis for the TCGA PAAD (pancreatic cancer) working group. The TCGA PAAD team performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic ductal adenocarcinoma specimens, including samples with characteristic low neoplastic cellularity. … Continued