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Cancer Model Systems Workshop: Part 2 Vertebrate Models
December 8, 2017 @ 1:00 pm - 3:00 pm
The Models Systems II workshop will focus on the use of mice to model human cancer, discussing traditional xenograft studies, genetically engineered models, and patient-derived tumor xenografts (PDXs). We will discuss models of KRAS-driven cancer (pancreatic, lung); prostate cancer via the PTEN-deletion model; GBM models for low grade and high grade tumors; and models for melanoma and renal cancer. We will discuss PDXs derived from pancreatic, breast, and bladder cancers. Advantages and disadvantages of each model will be discussed. Workshop will be led by Al Baldwin, Jen Jen Yeh, David Darr, Billy Kim, and Ryan Miller.