An Update on CAR T Therapy (Medical and Surgical Oncology Lecture)

Natalie Grover, MD

Assistant Professor
UNC Lineberger Comprehensive Cancer Center
UNC School of Medicine
University of North Carolina at Chapel Hill

Lecture Description

This lecture will give an overview of CAR-T cells, discuss recent clinical trial results and FDA approvals as well as current clinical applications. This lecture will also cover the management of the unique toxicities of CAR-T therapy. Finally, this lecture will discuss some of the ongoing trial of CAR-T therapy as well as future directions of the field.

Lecture Objectives:

• Discuss the current approved indications for CAR-T cells
• Describe presentation and management of unique toxicities associated with CAR-T therapy
• Describe challenges of developing CAR-T cells for solid tumors