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by sysadmin last modified Aug 20, 2011 03:54 PM
DNA replication protein also has a role in mitosis, cancer

DNA replication protein also has a role in mitosis, cancer

by Mary Ruth Helms last modified May 14, 2012 02:21 PM

The finding presents a possible explanation for why so many cancers possess not just genomic instability, but also more or less than the usual 46 DNA-containing chromosomes.

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Grant to fund use of kinase test in HER2-positive breast cancer

Grant to fund use of kinase test in HER2-positive breast cancer

by Mary Ruth Helms last modified May 15, 2012 03:49 PM

Chapel Hill, NC – Susan G. Komen for the Cure® has awarded a grant of almost $900,000 to Lisa A. Carey, MD, and Gary Johnson, PhD, to research clinical applications for the first broad-based test for protein kinase activation and response to inhibitory drugs in HER2-positive breast cancer.

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Study shows benefit of new maintenance therapy for multiple myeloma

Study shows benefit of new maintenance therapy for multiple myeloma

by Mary Ruth Helms last modified May 14, 2012 12:56 PM

Chapel Hill, NC – Multiple myeloma is a form of cancer where the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anemia, infection and kidney failure. A medical procedure called autologous hematopoietic stem cell transplantation, commonly known as a stem cell transplant, is frequently an important treatment option for many patients.

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Molecular subtypes and genetic alterations may determine response to lung cancer therapy

Molecular subtypes and genetic alterations may determine response to lung cancer therapy

by Mary Ruth Helms last modified May 11, 2012 10:01 AM

Chapel Hill - Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient’s individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient’s response to therapy.

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UNC Bone Marrow and Stem Cell Transplantation Program achieves outstanding outcomes

by Mary Ruth Helms last modified May 10, 2012 02:08 PM

Chapel Hill, NC –A medical procedure called allogeneic hematopoietic cell transplantation, commonly known as a bone marrow or stem cell transplant, is the only known curative option for many patients with life-threatening blood-borne cancers such as leukemia and lymphoma.

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Thriving on science: in depth with Jason Lieb

Thriving on science: in depth with Jason Lieb

by Mary Ruth Helms last modified May 11, 2012 10:21 AM

Jason Lieb likes to mix it up. A triathlete, he enjoys running, swimming and cycling. In his lab, he works in several model systems: yeast, round worms (C. elegans), fruit flies (Drosophila melanogaster) and human cell lines.

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Postdoctoral fellow receives DOD Visionary Fellowship Award

Postdoctoral fellow receives DOD Visionary Fellowship Award

by Mary Ruth Helms last modified May 08, 2012 01:05 PM

Idoia Garcia, PhD, a postdoctoral fellow in the lab of Timothy Gershon, MD, PhD, has been awarded a Department of Defense Visionary Postdoctoral Fellowship Award. The peer-reviewed award is intended to support exceptionally talented recent medical or other doctoral graduates in their pursuit of cutting-edge, innovative, high-risk/high-impact cancer research during their postdoctoral fellowship.

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Der receives grant funding for pancreatic cancer research

Der receives grant funding for pancreatic cancer research

by Mary Ruth Helms last modified May 08, 2012 09:56 AM

Channing Der, PhD, Sarah Graham Kenan Professor of Pharmacology, received a two-year $200,000 American Association for Cancer Research Innovative grant from the Pancreatic Cancer Action Network. His grant will fund research on the mechanism of ERK inhibition resistance and ERK-dependent pancreatic cancer.

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UNC scientist reports ways to improve breast cancer biomarker test

UNC scientist reports ways to improve breast cancer biomarker test

by Mary Ruth Helms last modified May 04, 2012 10:32 AM

American and Spanish researchers report potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests.

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Review study makes recommendations to enhance Cancer Comparative Effectiveness Research

by Mary Ruth Helms last modified May 03, 2012 03:41 PM

Which treatment for prostate cancer is most effective? Will a specific combination of cancer drugs increase patient survival for colon cancer? As the pace of scientific discovery continues to accelerate, patients and their providers face more choices and decisions about how to address their health care needs, and information that can help inform their decisions is often hard to find.

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Stem cells poised to self-destruct for the good of the embryo

Stem cells poised to self-destruct for the good of the embryo

by Mary Ruth Helms last modified May 09, 2012 09:55 AM

Embryonic stem cells are primed to kill themselves if damage to their DNA makes them a threat to the developing embryo. UNC researchers reveal how they do it.

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DeSimone elected into National Academy of Sciences

DeSimone elected into National Academy of Sciences

by Mary Ruth Helms last modified May 03, 2012 10:09 AM

Dr. Joseph DeSimone, PhD, Chancellor's Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill, has been elected into the National Academy of Sciences, one of the highest honors that a U.S. scientist or engineer can receive.

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Milowsky comments on new therapies for bladder cancer

Milowsky comments on new therapies for bladder cancer

by Ellen de Graffenreid (edegraff) last modified May 02, 2012 03:38 PM

Matthew Milowsky, MD, was recently quoted in the online journal Health News Digest on new therapies for bladder cancer.

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Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award

Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award

by Ellen de Graffenreid (edegraff) last modified May 02, 2012 01:47 PM

Joseph S. Pagano, MD, has been awarded the fifth annual Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research. Dr. Pagano is the director emeritus of UNC Lineberger Comprehensive Cancer Center.

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UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery

UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery

by Mary Ruth Helms last modified May 03, 2012 12:02 PM

Current nanomedicine research has focused on the delivery of established and novel therapeutics. But a UNC team is taking a different approach.

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36th Annual UNC Lineberger Scientific Symposium

by Ellen de Graffenreid (edegraff) last modified May 01, 2012 04:41 PM

UNC Lineberger’s 36th annual scientific symposium drew large crowds, with over 450 participants.

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New book summarizes state of eHealth applications

New book summarizes state of eHealth applications

by Ellen de Graffenreid last modified May 01, 2012 08:49 AM

UNC’s Seth Noar examines intersection of technology and health

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Armistead receives Mentored Clinical Scientist Development Award

Armistead receives Mentored Clinical Scientist Development Award

by Ellen de Graffenreid last modified Apr 24, 2012 04:36 PM

Paul Armistead, MD, PhD, has received a grant of more than $396,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study leukemia stem cell-associated minor histocompatibility antigens.

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