The University Cancer Research Fund (UCRF) is a nation-leading investment to stimulate cancer research and reduce North Carolina’s leading cause of death. The Fund builds upon the exceptional research base at UNC Lineberger Comprehensive Cancer Center, the state’s only public, NCI-designated comprehensive cancer center.

UCRF’s Goal

To create a nation-leading cancer research effort and to reduce North Carolina’s cancer burden. UCRF is accomplishing these goals through:

  • Discovery to better understand the causes and course of cancer;
  • Innovation to create new and better ways to prevent, diagnose and treat cancer; and by stimulating
  • Delivery of improved cancer care, screening and prevention across the state.
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Latest News

  • UNC Lineberger's Anthony Amelio, PhD.

    Researchers use genetic insights to develop model for HPV-linked head and neck cancer

    A University of North Carolina Lineberger Comprehensive Cancer Center-led research team has used genetic insights about head and neck cancers linked to HPV, or human papillomavirus, to improve laboratory tools for studying the disease. Leveraging their discovery that different subtypes of HPV-linked oropharyngeal squamous cell carcinoma exist based on the expression levels of two different … Continued

  • Can scientists predict which cancer markers are likely to trigger an immune response?

    Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have designed and validated a model for predicting what might make an effective cancer vaccine against a patient’s tumor. This finding could help overcome a significant obstacle in the development of personalized cancer vaccines. In a study published in the journal Cancer Immunology Research, … Continued

  • Researchers unveil experimental compound to block therapeutic target in blood cancer

    Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer. They also developed an experimental therapeutic to block the signal and slow tumor growth. In the journal Proceedings of the National Academy of Sciences, the researchers reported they have identified a … Continued

  • UNC Lineberger's Anthony Amelio, PhD.

    Amelio published in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

    A new study led by UNC Lineberger’s Antonio “Tony” Amelio, PhD, and colleagues was published in the journal Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, and featured on the cover of the July issue. Amelio is an assistant professor in the UNC Adams School of Dentistry Division of Oral and Craniofacial Health Sciences. … Continued

  • Scientists publish overview of the latest in cancer vaccine target research

    University of North Carolina Lineberger Comprehensive Cancer Center researchers have published a review of experimental cancer vaccines that identified areas of promise and challenges for the field. In the Nature Reviews Cancer, researchers outlined current research into targets for therapeutic cancer vaccines, an area of active investigation focused on boosting immune responses to cancer. “Generally, … Continued

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