UCRF News - UNC Lineberger

Group shot of UNC Lineberger Community Advisory Board members.

Community Advisory Board engages NC communities in the fight against cancer

UNC Lineberger’s Community Advisory Board works to make sure cancer research reflects community needs across the state, and to raise public awareness of cancer’s signs and symptoms.

Patients using smartphones, tablets and laptops to report symptoms.

Building tools to help doctors better track patient symptoms, improve outcomes

Digital reporting technologies created by UNC Lineberger researchers are now being used in North Carolina and across the country to improve care and outcomes for cancer patients.

UNC Lineberger's Lisa Carey and Chuck Perou.

UNC Lineberger continues its national leadership in breast cancer research

UNC Lineberger researchers are leading next-generation clinical breast cancer trials as part of a national project using cutting-edge technologies to track tumor changes in real time.

Chad Pecot, MD, and Kristina Whately, PhD, work in the Pecot Lab.

‘If you’re trying to make a difference in cancer, you can’t go slow’

Chad Pecot, MD, leads cancer RNA research at UNC Lineberger, creating innovative therapies and promising treatment strategies for multiple cancer mutations.

Single strand ribonucleic acid, RNA research and therapy.

Uniquely engineered KRAS-targeted cancer drug found to be effective in early studies

Chad Pecot, MD, and colleagues have demonstrated that a uniquely engineered drug that zeroes in on a mutated gene called KRAS G12V could potentially stop KRAS-dependent cancers in their tracks.

UNC researchers discover an enzyme that protects DNA during rapid cell divisions

Michael Emanuele, PhD, and colleagues have discovered that an enzyme called USP37 plays a crucial role in ensuring our cells copy their DNA correctly.

Ewing's sarcoma that has metastasized to the pleura fluid.

Researchers develop molecule that targets Ewing sarcoma

Pengda Liu, PhD, and colleagues have created a small molecule that targets and breaks down a protein linked to Ewing sarcoma, an aggressive cancer that mostly affects children and teens.

Human cells with acute myelocytic leukemia (AML) in the pericardial fluid, shown with an esterase stain at 400x magnification.

Adaptive whole-genome sequencing could transform childhood leukemia diagnosis

UNC Lineberger researchers have demonstrated a faster, more cost-effective approach to analyzing the genetic makeup of pediatric acute leukemia. Determining a cancer’s genomic classification is critical to developing a more effective treatment plan tailored to a patient’s tumor.