The publication names the cancer center as one of the top 100 oncology programs in the nation.
Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not understood the mechanisms that underlie it.
The article profiles Russell Tatum, a father who found emotional support for himself and his family through the UNC Lineberger-supported group designed for fathers who have lost a spouse to cancer.
Michael Pignone will join fellow experts in evidence-based medicine from many health-related fields to rigorously review existing peer-reviewed evidence and evaluating the benefits and harms of preventive services.
Preclinical study shows potential of new technologies to detect response to cancer therapy earlier
A set of towlettes developed by two researchers at Carolina can safely remove difficult-to-clean anticancer drugs commonly found on surfaces in hospitals, pharmacies, clinics and labs. The product, called Hazardous Drug Clean – or HDClean – addresses the growing concern regarding the safety of health care workers who frequently handle these potentially dangerous drugs.
The Triangle Business Journal has named two UNC Lineberger members as finalists for the 2013 Health Care Heroes Awards.
North Carolina’s community colleges are important settings for educating and training our citizens. Can they also play a role in preventing cancer? A group of UNC researchers recently looked into the question of whether community colleges could spread the latest evidence-based cancer and wellness information to the thousands of employees and students of the state’s community college system.
Leah Ranney, PhD, associate director of the UNC Tobacco Prevention and Evaluation Program, and Adam Goldstein, MD, professor in UNC Family Medicine and director of the Tobacco Prevention and Evaluation Program, published the following editorial on the social benefits of anti-smoking policies and tobacco-use prevention programs:
Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) hide within the worldwide human population. While dormant in the vast majority of those infected, these active herpesviruses can develop into several forms of cancer. In an effort to understand and eventually develop treatments for these viruses, researchers at the University of North Carolina have identified a family of human genes known as Tousled-like kinases (TLKs) that play a key role in the suppression and activation of these viruses.
Ethan Basch, MD, MSc, Director of Cancer Outcomes Research at the UNC Lineberger Comprehensive Cancer Center, has been appointed by the Director of the National Cancer Institute to serve on the Board of Scientific Advisors (BSA).
What’s most important to a man as he decides whether or not to undergo prostate-specific antigen- PSA- screening for prostate cancer? What does he value most about the screening? And what’s the best way to present the information to help him make an appropriate decision for himself?
In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth in mice using a gene closely linked to these processes.
More than 150 physicians and patients gathered February 6th and 7th to learn more about melanoma. Melanoma Patient Day, February 6, was a half-day symposium sponsored by the Melanoma Research Foundation, the UNC Division of Surgical Oncology and the UNC Department of Dermatology. Meeting co-chairs were Drs. David Ollila, professor of surgery, and Nancy Thomas, Robert Alan and Irene Briggaman Distinguished Professor of Dermatology.
Worldwide, many strains of the bacterium Staphyloccocus aureus are already resistant to all antibiotics except vancomycin. But as bacteria are becoming resistant to this once powerful antidote, S. aureus has moved one step closer to becoming an unstoppable killer. Now, researchers at the University of North Carolina at Chapel Hill have not only identified the mechanism by which vancomycin resistance spreads from one bacterium to the next, but also have suggested ways to potentially stop the transfer.
UNC researchers find a way to unlock the secrets of DNA’s dark matter.
A new study from the University of North Carolina published January 25, 2013 in the journal Genome Medicine reveals the huge diversity of U.S. biobanks and also raises questions about the best way to manage and govern them
The Triad Golfers Against Cancer has awarded two grants to researchers at the UNC Lineberger Comprehensive Cancer Center totaling $65,000.
A University of North Carolina School of Medicine study may have implications for thwarting the effects of bioterrorism attack with lethal microbes, as well as finding a way to save people in septic shock, an overwhelming bacterial infection of the blood.
The Scientist Magazine has featured recent research by Timothy Gershon, MD, PhD, on the link between brain tumors and glycolysis.
The 2012 University Cancer Research Fund Innovation Awards recognize six University of North Carolina researchers for groundbreaking cancer research. The UCRF Innovation Awards are designed to support innovation, collaboration and cancer-focused science across a broad spectrum of the cancer-research community at UNC.
Norman Sharpless, MD, Wellcome Distinguished Professor of Cancer Research and Deputy Cancer Center Director, discussed the development of a mouse model to study aging and cancer with WUNC's Frank Stasio.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, spoke to National Public Radio's All Things Considered about the need to find a balance between making genetic data available to researchers and protecting patient privacy.
Dr. Qi Zhang receives the 2013 Basil O’Connor Starter Scholar Research Award from the March of Dimes Foundation.
Joseph DeSimone, PhD, was awarded the 2012 Watson Chubb Award for Innovation from the Sigma Xi, The Scientific Research Society. The award honors creativity among scientists and engineers.
A 2009 survey by UNC faculty of North Carolina middle and high schoolers found that 79 percent support smoke-free areas and other smoking bans.
The best approach to detecting cervical cancer in HIV-positive women living in research limited countries such as those in Sub-Saharan Africa combines commonly used testing methods tailored to local levels of development and medical infrastructure, according to a study by researchers from and the University of Witwatersrand in South Africa and the University of North Carolina.
Jenny Ting, PhD, Alumni Distinguished Professor in UNC’s Department of Microbiology and Immunology and member of UNC Lineberger, has been awarded the American Association of Immunologist’s Life Technologies Meritorious Career Award for 2013.
This month's focus is on the ever-popular mode of entertainment enjoyed throughout the centuries: the theater. Keith Burridge, a Kenan Professor of Cell Biology and Physiology, is also a playwright. His most recent play, The Art of Deception, is based on a true story of a dutch painter, Han van Meegeren.
CHAPEL HILL, N.C. – Research findings from the University of North Carolina School of Medicine are shining a light on an important regulatory role performed by the so-called dark matter, or “junk DNA,” within each of our genes.
Endeavors: Yang finds new link between health and connectivity to friends, family, and social groups
From UNC Endeavors - The arthritis and chronic back pain are so intense that the patient can barely get through the day. The patient’s blood work reveals that his body is in a state of chronic inflammation, a sign that his immune system is working too hard. Doctors prescribe medication, which helps a little, but it won’t address one contributing factor that sociologist Yang Yang says doctors aren’t trained to consider.
The Komen Foundation named Hyman B. Muss, MD, Professor of Medicine and the Director of the Geriatric Oncology Program at University of North Carolina Lineberger Comprehensive Cancer Center in Chapel Hill as one of two recipients of their Brinker Ward in 2012.
Satish Gopal, MD, MPH, assistant professor in the divisions of hematology/oncology and infectious diseases at the UNC School of Medicine, has been awarded a 2012 AIDS Malignancy Consortium (AMC) fellowship. The fellowship helps foster the careers of new and junior investigators whose work involves clinical research trials on HIV-associated malignancies in resource-limited settings.
Wang discovers information from outside the genome influences stem cell differentiation, cancer development
Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute to the development of a specific organ like a heart, lung, or kidney. Research from the University of North Carolina at Chapel Hill School of Medicine has shed new light on how epigenetic signals may function together to determine the ultimate fate of a stem cell.
Use the links below to find the news archives.
Dr. Carey talks about the importance of cancer research and her new role as Chief of the Division of Hematology and Oncology and Physician-in-Chief of the N.C. Cancer Hospital.
N.E.D. - a rock band comprised of gynecologic oncology physicians - was featured in the New York Times' health and science blog.
The American Association for Cancer Research and Kure It have announced that William Y. Kim, MD, will receive a 2012 AACR-Kure It Grant for Kidney Cancer Research.
Nikolay Dokholyan, PhD, Professor of Biochemistry and Biophysics and member of the UNC Lineberger Comprehensive Cancer Center, was elected as a 2012 Fellow of the American Physical Society. The Dokholyan lab studies the physical nature of interactions between atoms, molecules, cells, and organisms. The underlying question throughout their research is how these interactions shape the complex organization, behavior, and evolution of biomolecules and organisms.
Hepatitis C virus has evolved to invade and hijack the basic machinery of the human liver cell to ensure its survival and spread. Researchers at the University of North have discovered how hepatitis C binds with and repurposes a basic component of cellular metabolism known as a microRNA to help protect and replicate the virus.
The UNC Global Oncology Program held its third annual retreat on December 14 at the Friday Center. Led by Dr. Blossom Damania, Director of the UNC Lineberger Global Oncology Program, and Dr. Dirk Dittmer, Program Resource Director for the program, close to 80 program members from the UNC Center for AIDS Research and UNC Lineberger shared their research.
For Dr. Neil Hayes “the best part of being a scientist is the people. Here at UNC, it’s the leadership we have for the cancer center in clinical fields, the wonderful scientists across the country who we collaborate with, and our patients.”
Dr. Lisa Carey, Marilyn Jacobs Preyer Distinguished Professor in Breast Cancer Research, and Barbara Martin, Health-e-NC Project Director, will discuss surviving breast cancer on the next episode of UNC’s Your Health with Adam & Cristy.
ABC 11 recently featured the UNC Comprehensive Cancer Support Program's Caregiver Support Group.
The UNC Lineberger Geriatric Oncology Program held its third annual retreat on November 29 at the Friday Center. Program members presented research and heard scientific presentations from colleagues at Duke and Wake Forest Universities. The group then discussed areas of possible collaboration.
Kurt Ribisl, PhD, has been appointed to lead the Cancer Prevention and Control Program at the UNC Lineberger Comprehensive Cancer Center.
An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively make designer drugs that hit multiple protein targets at once.
Brook Zickus’ wedding bouquet featured an unusual “something blue”: a UNC Lineberger ribbon-foot pin.
Basch discusses the value of patient-reported data in comparative effectiveness research in two webinars Dec. 11 and 12
Ethan Basch, MD, Director of the Cancer Outcomes Research Program at UNC Lineberger Comprehensive Cancer Center, will be speaking in two webinars on comparative effectiveness on Tuesday, Dec. 11 and Wednesday, Dec. 12.
The annual compilation of The Best Doctors in America® includes more than 60 physicians affiliated with the University of North Carolina’s Lineberger Comprehensive Cancer Center.
Yang Yang, PhD, associate professor of sociology and member of UNC Lineberger, was quoted about a Journal of Urology study that found that men have a higher death rate from cancer.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, was quoted on National Public Radio's All Things Considered discussing a report in American Journal of Human Genetics finding that healthy people have many genetic mutations.
Terry Magnuson served on an Institute of Medicine commission tasked to review the progress of California’s state-funded regenerative medicine initiative focused on stem cell research.
Chapel Hill, NC – Norman E. “Ned” Sharpless, MD, has been appointed Deputy Director of the UNC Lineberger Comprehensive Cancer Center. Dr. Sharpless is the Wellcome Distinguished Professor in Cancer Research, professor of medicine and genetics.
Federico Innocenti, MD, PhD, received the 2013 Leon I. Goldberg Young Investigator Award from the American Society for Clinical Pharmacology and Therapeutics. Innocenti, associate director for oncology research in the UNC Institute for Pharmacogenomics and Individualized Therapy and a member of UNC Lineberger, was recognized for his work in individualizing therapy for cancer patients.
The American Association for the Advancement of Science has awarded three UNC Lineberger Comprehensive Cancer Center members the distinction of AAAS 2012 Fellow. The three were among four UNC School of Medicine Faculty honored.
Stacey Anderegg is an Hematology/Oncology Infusion Nurse at the N.C. Cancer Hospital. In her life outside the hospital, Stacey is a vocalist with a 7 woman a cappella group called "Stella."
Dr. Lisa Carey, MD, medical director of the UNC Breast Center and associate director for clinical science at UNC Lineberger Comprehensive Cancer Center, spoke to MedPage Today about a recent Centers for Disease Control study that reported that black patients had a 41 percent higher mortality than their white counterparts, despite having a lower incidence of the disease.
The protein Ras plays an important role in cellular growth control. Researchers have focused on the protein because mutations in its gene are found in more than 30 percent of all cancers, making it the most prevalent human oncogene.
Chapel Hill, NC – In a paper published in the Nov. 21 issue of Cell, a team led by Mauro Calabrese, a postdoctoral fellow at the University of North Carolina in the lab of Terry Magnuson, chair of the department of genetics and member of the UNC Lineberger Comprehensive Cancer Center, broadens the understanding of how cells regulate silencing of the X chromosome in a process known as X-inactivation.
Neil Hayes, MD, MPH, talks to North Carolina Now about new research into lung cancer. The interview aired on the show's Nov. 12, 2012 broadcast.
Chapel Hill, NC – Ethan Basch, MD, has joined the Lineberger Comprehensive Cancer Center at the University of North Carolina School of Medicine. Basch will be an associate professor of medicine and director of the cancer outcomes research program.
Two UNC Board of Trustees members and longtime UNC Lineberger supporters were among the seven honored with the William Richardson Davie Award. The Davie Awards are the highest honor bestowed by the UNC Board of Trustees.
The 2012 Comprehensive Cancer Support Program Support Week was a huge success. Hundreds of patients and caregivers learned about and participated in activities highlighting the many support services of the Comprehensive Support Program during CCSP Support Week 2012.
UNC Lineberger Comprehensive Cancer Center and UNC Cancer Care honored four employees with 2012 Excellence Awards.
Andrew F. Olshan, PhD, has been appointed Associate Director of Population Sciences at UNC Lineberger Comprehensive Cancer Center. This senior leadership position is responsible for overseeing the development of population-based cancer research and its integration throughout the Cancer Center programs. The position also oversees several Cancer Center core resources as well as two established scientific programs, Cancer Epidemiology and Cancer Prevention and Control. Dr. Olshan will continue to serve as head of the Cancer Epidemiology Program and directs two cores, the Biospecimens Processing Facility and Rapid Case Ascertainment Core.
Valerie King is living the teenage dream, she's in the running for homecoming queen. While it's tough competition for the crown, it's nothing compared to the battle she's been fighting for the past year.
Shelley Golden, MPH, and Jo Anne Earp, ScD, co-wrote an article that received the Lawrence W. Green Paper of the Year Award at the 63rd annual meeting of the Society for Public Health Education (SOPHE), held Oct. 25-27 in San Francisco.
Lilly Oncology on Canvas Art Exhibit on display in the N.C. Cancer Hospital Lobby November 7-21, 2012
UNC Lineberger Comprehensive Cancer Center is hosting the Lilly Oncology on Canvas Exhibition in the lobby of the N.C. Cancer Hospital.
Elizabeth D. Green has joined UNC Lineberger Comprehensive Cancer Center’s Office of External Affairs in the role of major gifts officer. She will work with UNC Lineberger supporters, faculty and staff to enhance awareness of and private support for cancer prevention, research and treatment programs at UNC Lineberger and the N.C. Cancer Hospital.
The chief of cardiology in the University of North Carolina School of Medicine and member of UNC Lineberger has been elected president of the Association of Professors of Cardiology.
UNC researchers discover the first link between epigenetic tags—the chemicals that orchestrate how our genes are expressed and our health maintained or derailed.
A new website for Single Fathers Due to Cancer has been launched as a way to help fathers more easily find resources and support.
Dr. Lisa Carey was featured by the Susan G. Komen Foundation as part of its 31 Days of Impact series that profiled men and women who are inspirational in the fight against breast cancer.
Genetic Engineering and Biotechnology News interviwed Howard McLeod, PharmD, about the role of physicians and insurance companies in gauging chemotherapy dosages in an article titled "Chemotherapy for the 21st Century" published Oct. 31, 2012.
Linda Van Le, MD, professor of gynecologic oncology and member of the UNC Lineberger Comprehensive Cancer Center, has been appointed the Leonard Palumbo Distinguished Professor of Gynecologic Oncology. This professorship was established in 1986 in honor of Dr. Leonard Palumbo. Because of Dr. Palumbo's long standing commitment to gynecologic oncology it was the family's wish that this professorship be designated as a professorship in gynecologic oncology. Dr. Wesley Fowler, Jr. held the professorship during his nearly forty years of dedicated service to the UNC Department of Obstetrics and Gynecology.
Mark C. Weissler, MD, FACS, was elected vice-chair of the Board of Regents of the American College of Surgeons (ACS) during the organization’s 2012 Clinical Congress in Chicago on Sept 30.
Lawrence B. Marks, MD, has been elected to a two-year term on the Board of Directors of the American Society for Radiation Oncology (ASTRO).
The Raleigh News and Observer interviewed Leslie Parise, PhD, professor and chair of the department of biochemistry, and Tina Leisner, PhD, a UNC research associate in biochemistry, about their research into the linkage between breast cancer and the protein CIB1.
Keith Amos, MD, FACS, was interviewed by UNC-TV’s Black Issues Forum on community education about breast cancer in the African American community on Sunday, Oct. 28.
Look at a typical directory of cancer support groups and you’ll find listings for cancer types, survivorship, and coping. But not too many lists include groups for caregivers.
There are Top 20 lists for music, books and for articles written about lay health advisors, as reported by the BioMedLib “Who is Publishing in My Domain?” journal.
Located at the center of campus, the new Genome Sciences Building will help researchers unlock the underlying mechanisms of cancer, in addition to providing space for other groundbreaking research.
Asheville artist Ann Hartline was featured in Family House Diaries in July 2011. Despite new medical challenges over the past year, Ann celebrated five years of living life large with metastatic breast cancer.
Close to 150 faculty and postdoctoral fellows gathered at the Kenan Center for the 37th annual UNC Lineberger Postdoc-Faculty Research Day
This year’s speaker was Dr. Brooke McCartney, associate professor in the department of biological sciences at Carnegie Mellon University. She completed her postdoc training in the lab of Dr. Mark Peifer.
Ronald Chen, MD, MPH, assistant professor of Radiation Oncology in the UNC School of Medicine and Bryce Reeve, PhD, associate professor of Health Policy and Management in the Gillings School of Global Public Health have been awarded a four-year, $1,124,226 grant by the National Cancer Institute (NCI). This grant supplements a parent study funded by the Agency for Healthcare Research and Quality (AHRQ) to monitor the recovery, mental well-being and quality of life of prostate cancer patients during the two years following treatment. Both researchers are members of UNC Lineberger Comprehensive Cancer Center.
Patient perspective key to adequate evaluation of cancer treatment
Election to the IOM is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.
Satish Gopal, MD, MPH, assistant professor in the division of hematology/oncology and infectious diseases at the UNC School of Medicine, has received a five-year International Research Scientist Development Award (IRSDA) from the Fogarty International Center of the National Institutes of Health.
A brilliant and beloved scientist has left us too early. Dr. Robert Millikan, Barbara Sorenson Hulka Distinguished Professor of Cancer Epidemiology, died Sunday, October 7. He was 55.
William Valdar, PhD, assistant professor of genetics, has received a 5-year, $1.4 million grant from the National Institute of General Medical Sciences (part of the National Institutes of Health), to develop statistical methods and software to support the design and analysis of experiments that use the Collaborative Cross, a “library” of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.
Drs. Davis, Lieb and Rathmell, all members of UNC Lineberger, are featured in an article on V's Voice, the blog for The V Foundation for Cancer Research.
The North Carolina Biotechnology Center recently awarded the Society for Translational Oncology (STO) $5,000 to be used for the organization's annual meeting. This year's meeting "Personalizing Cancer Diagnosis and Treatment 2012" will be held October 20-21 at UNC Lineberger.
Andrew Wang, MD, assistant professor of radiation oncology, has been awarded a $50,000 one-year grant from the Lung Cancer Research Foundation.
Chapel Hill, NC – Christophe Guilluy, PhD, Wenjin Liu, PhD and JinZhu Duan, PhD are the first, second, and third place recipients of the Joseph S. Pagano Award for a paper by a postdoctoral fellow published in 2011.
WCHL named UNC Lineberger director Shelley Earp, MD, the Village Pride Award Honoree for October 2, 2012. Each weekday the station selects a Hometown Hero who goes “over and above the call of duty,” exemplifying excellent service and dedication to others in the community.
Chapel Hill, NC – More than 50 Chapel Hill and Carrboro businesses and community groups are turning the towns pink during the months of September and October to raise funds for UNC Lineberger Comprehensive Cancer Center and its Comprehensive Cancer Support Program.
New research from UNC has established the first link between the two most fundamental epigenetic tags -- histone modification and DNA methylation -- in humans.
DALLAS -- An American clinician-scientist and an Israeli researcher whose work has led to more personalized treatments for breast cancer are being honored as this year’s winners of the prestigious Susan G. Komen for the Cure® Brinker Awards for Scientific Distinction in Basic Science and Clinical Research, the highest awards of merit given by the world’s leading breast cancer organization.
Blossom Damania, PhD, and Dirk Dittmer, PhD, both have lived all over the world, where they saw firsthand the global burden of cancer. Both are professors of microbiology and immunology in the UNC school of Medicine and members of UNC Lineberger.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, provided his perspective on a HuffPost Live broadcast that aired on September 24, 2012.
Team identifies genetic causes and similarity to ovarian cancer
Carey named Division Chief of Hematology-Oncology and Physician-in-Chief of the N.C. Cancer Hospital
Chapel Hill - Lisa A. Carey, MD, has been appointed Chief of the Division of Hematology and Oncology at the University of North Carolina School of Medicine and Physician-in-Chief of the N.C. Cancer Hospital.
Chapel Hill, NC – The cost of sequencing the entire human genome, or exome – the regions of the genome that are translated into proteins that affect cell behavior – has decreased significantly, to the point where the cost of looking at the majority of a patient’s genomic data may be less expensive than undertaking one or two targeted genetic tests.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in NPR's second story in its "$1,000 Genome" series, which aired today.
Chapel Hill, NC –Researchers have long known that individual diseases are associated with genes in specific locations of the genome.
Preclinical testing a necessary step in drug development
UNC Lineberger faculty co-author review article on adjuvant chemotherapy in women 70 years of age and older
Dr. Angelique Whitehurst, assistant professor of pharmacology, was awarded a 2011 Innovative Research Grant from Stand Up to Cancer, the scientific partner of the American Association of Cancer Research.
Chapel Hill, NC – A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.
Changes in DNA that are important to the initiation and progression of lung cancer also identified by NIH-supported researchers
Wanda Wooten talks with NBC 17 about the day she was diagnosed with ovarian cancer and her treatment and offers encouragement to other women facing ovarian cancer.
The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C.
UNC scientists were co-principal investigators and collaborators for projects described in the September 6, 2012 special issue of the journal Nature describing the ENCODE (Encyclopedia of DNA Elements) Project.
GeneCentric now has two separate exclusive licenses to diagnostic technologies from the University of North Carolina at Chapel Hill. The company was co-founded in 2011 by UNC Lineberger researchers Drs. Charles Perou and Neil Hayes, who discovered molecular signatures critical in distinguishing clinically relevant subtypes of lung cancer.
UNC-Chapel Hill rose to ninth from 16th among leading private and public research universities for the level of federal funding ($545.99 million) devoted to research and development in all fields during fiscal 2010.
UNC Head Basketball Coach Roy Williams and UNC Lineberger physician-scientist Kim Rathmell, MD, PhD, were featured speakers at the American Cancer Society’s Cancer Action Network breakfast, held August 24th in Research Triangle Park.
Kayaking and rock climbing aren’t usual clinical activities for UNC Lineberger medical oncologist Dr. Juneko Grilley-Olson and nurse practitioner Elizabeth Sherwood, but they were during the time that each volunteered for a First Descents camp week for young adult cancer survivors.
Chapel Hill, NC – A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been well-understood.
Chapel Hill, NC – Leukemia and lymphoma patients who receive life-saving stem cell or bone marrow transplants often experience chronic side effects that significantly decrease quality of life, can last a lifetime, and ultimately affect their long-term survival.
The V Foundation for Cancer Research, one of the nation’s leading cancer research foundations, has awarded a $600,000 grant to a UNC Lineberger team.
A Randolph County woman with leukemia receives stem cells from her youngest brother in hopes of restoring her health and returning to work as a baker.
Hy Muss, MD, and Debra Bynum, MD, co-authored an editorial in the July 20, 2012 issue of the Journal of Clinical Oncology.
A UNC-led team of scientists describes the function of a previously uncharacterized protein that dramatically influences inflammation.
Chapel Hill, NC – Carmina G. Valle, MPH, is the recipient of the first Marci Kramish Campbell Dissertation Award, a competitive $5,000 award to recognize excellence in dissertation research focused on cancer and the population sciences.
Joseph DeSimone, PhD, Chancellor's Eminent Professor of Chemistry, gave an interview to EarthSky regarding his green inventions, his current work and the future of science.
Nick McCrory, the son of Ana and Doug McCrory, won a bronze medal in the Olympic men’s 10-meter synchronized diving competition with partner David Boudia. Nick’s mother, Ana, works in the UNC Lineberger Tissue Culture Facility.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in an article on NPR's website discussing a recent request by a genetic test maker for the Food and Drug Administration to approve its personalized DNA test.
Life is full of choices, and even cells come to a fork in the road. They have to decide what to do about damage to their DNA: repair the damage, force the damaged cell to die, or allow the damage to transform the cell to a tumor cell.
Three UNC graduate students were awarded International Predoctoral Fellowships by the Howard Hughes Medical Institute. Onur Dagliyan, Alakananda Das, and Mira Pronobis each received a $43,000 fellowship.
Three UNC Lineberger researchers are collaborating on a project recently awarded more than $3.3 million over five years from the National Institutes of Health’s National Heart, Lung, and Blood Institute.
Vaccines against human papillomavirus (HPV) are now recommended by the Centers for Disease Control and Prevention for both teenage boys and girls. The vaccine protects against the two most common types of the virus that cause cervical cancer: HPV 16 and 18. Is there a chance that the increased number of people vaccinated might result in an increase of other types of HPV that cause cancer?
Ana McCrory of the Tissue Culture Facility will be making a special trip to London in July. She, her husband, Doug, their son, Lucas, and other family members are traveling to cheer on her son, Nick, who is a member of the 11-member US diving team for the 2012 Summer Olympics.
Dittmer selected to serve as chair of AIDS-Associated Opportunistic Infections and Cancer Study Section
Dirk Dittmer, PhD, professor of microbiology and immunology, has been selected to serve as chair of the AIDS-Associated Opportunistic Infections and Cancer Study Section, for the Center for Scientific Review, a program of the National Institutes of Health.
RALEIGH, NC – Crown Imports announced today that the highly successful “Corona Cares” charitable donation program in North Carolina will kick off on August 1 to benefit patient and family support programs at the N.C. Cancer Hospital. Over the past two years, “Corona Cares” has provided more than $210,000 for these programs.
The Cancer Genome Atlas generates genomic data for colon and rectal cancers that point to potential targets for treatment.
Overall, eleven specialties at UNC Hospitals were recognized as nationally ranked or high performing by U.S. News & World Report in its annual "America's Best Hospitals" issue.
The University of North Carolina at Chapel Hill’s Frank Hawkins Kenan Institute of Private Enterprise has appointed Joseph M. DeSimone as its new director.
Rachel Roper, PhD, Associate Professor of Microbiology & Immunology at East Carolina’s Brody School of Medicine has been granted a patent for her discovery of a poxvirus gene that, when deleted, significantly weakens the vaccine virus while simultaneously increasing immune responses to it.
Keith Amos, MD, assistant professor of surgery at UNC-Chapel Hill, is quoted in an ABC News feature discussing a new study about partial breast removal surgery to treat cancer.
John Strader, PA-C with the hematologic malignancies program, was honored as the 2012 Man of the Year by the Leukemia & Lymphoma Society, North Carolina chapter, raising over $30,000 for the organization.
Chapel Hill - From the air, the twists and turns of rivers can easily be seen. In the body, however, tracing the twists and turns of blood vessels is difficult, but important. Vessel “bendiness” can indicate the presence and progression of cancer.
Researchers at UNC have proposed a novel interpretation of an old biomarker which, if validated, could fundamentally transform the management of head and neck cancer.
CHAPEL HILL, NC – Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system.
When scientists and advocates join forces, good things can happen. Dr. Channing Der, Sarah Graham Kenan Professor of Pharmacology and UNC Lineberger faculty member, and Lori Matteson, a Raleigh pancreatic cancer survivor and advocate, joined over 600 other pancreatic cancer advocates and family members on a visit to Washington, DC.
Karyn Stitzenberg, MD, MPH, has been appointed to a four-year term on the North Carolina Advisory Committee on Cancer Coordination and Control.
A diet based on American junk food could lead to more obesity-induced inflammation than a diet high in animal fat, according to a new study by researchers at the University of North Carolina at Chapel Hill.
Increased fatty acid synthesis is a metabolic signature of non-Hodgkin lymphoma
Bruce Ham heard about the “Support Program for Single Fathers” from a friend. “I attended the first meeting. The guys in the group were going through exactly what I was going through and they were a similar age, they had all lost their wives to cancer, they all had kids in the house, so we had a lot in common. That’s what made it appealing to me.”
CHAPEL HILL, NC – Sometimes, technology progresses faster than our ability to take advantage of it.
Parking difficulties inspired Barbara Riff to take motorcycle lessons with her son. Now she commutes to work via motorcycle and frequently takes motorcycle trips for fun.
New JAMA study shows stepped-care intervention results in weight loss at lower cost, UNC's Deborah Tate co-author
A customized weight loss program may cost less to implement – despite having similar results – than a traditional weight loss program, according to a study published in the June 27 issue of The Journal of the American Medical Association (JAMA).
UNC Lineberger honored five clinical fellows for their research accomplishments and clinical excellence.
What are cancer rumors and why do people share them?
Todd Auman, PhD, has been appointed director of UNC Lineberger Comprehensive Cancer Center’s Tissue Procurement Facility.
A new analysis done by University of North Carolina at Chapel Hill researchers has found that physical activity - either mild or intense and before or after menopause - may reduce breast cancer risk, but substantial weight gain may negate these benefits.
Presents invited lecture at Harvard Medical School
Newly-Formed Collaboration to Focus on Vaccines and Inhaled Therapeutics
Genetic Marker in the Vitamin D Receptor Gene Associated With Increased Overall Survival for Pancreatic Cancer Patients
By Jeremy Moore
Following a blood stem cell transplant, survivors can face serious economic challenges that may negatively affect their quality of life.
Lisa Carey, MD, authored an editorial, titled “Neoadjuvant Trials of Human Epidermal Growth Factor Receptor 2 Targeting: How Many Drugs Do We Need?”
Carey Anders, MD, and William Kim, MD, were awarded grants from the Damon Runyon Cancer Research Foundation.
A gene known to be mutated in many different cancers, but thought to be relatively unimportant in melanoma, may be a key indicator of how the disease will respond to radiation therapy and whether it will spread.
Votes, not baskets, will propel Cornucopia House to the Final Four in a national competition for a $25K mobile technology grant from AtlanticBT.
Chapel Hill, NC – Debbie C. Dibbert, Director of External Affairs at UNC Lineberger Comprehensive Cancer Center, has been elected president of the National Association of Cancer Center Development Officers (NACCDO). She will serve a two-year term.
CHAPEL HILL, N.C. – A recent clinical trial testing a combination therapy for basal-like (also known as triple-negative) breast cancer demonstrates that a combination of two drugs with promising preclinical results is not as effective as researchers had hoped.
Chapel Hill, NC – Why do some cancers spread rapidly to other organs and others don’t metastasize? A team of UNC researchers led by Norman Sharpless, MD, have identified a key genetic switch that determines whether melanoma, a lethal skin cancer, spreads by metastasis.
WCHL named Jennifer Bowman a Hometown Hero for June 11, 2012. Each weekday the station selects a Hometown Hero who goes “over and above the call of duty,” exemplifying excellent service and dedication to others in the community.
Deborah Mayer, PhD, RN, AOCN, FAAN, associate professor in the UNC School of Nursing, has been appointed to a three-year term on the Cancer Survivorship Committee of the American Society of Clinical Oncology.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in an article discussing the fetal genome and the possibility of clinic procedures being introduced in the next couple of years.
Kurt Ribisl, PhD, is co-author of the article “Internet Alcohol Sales to Minors” published online ahead of print in the May 2012 issue of the Archives of Pediatrics & Adolescent Medicine.
Victoria Bae-Jump, MD, PhD, has received a two-year $200,000 grant from the Department of Defense, to study “Preclinical and Clinical Investigations of the Impact of Obesity on Ovarian Cancer Pathogenesis.”
Congratulations to the N.C. Children’s Hospital for receiving top rankings in 10 out of 10 clinical categories in U.S. News & World Report’s 2012-13 “America’s Best Children’s Hospitals” list. The N.C. Children’s Hospital is ranked 26th in cancer.
More than 150 faculty, students, and fellows gathered in the Alumni Center to hear talks on HPV and Cancer given by UNC Lineberger scientists from basic, translational science, clinical, population science, and global perspectives.
UNC surgeon-scientist Dr. Nancy DeMore says, “As a physician, I’m acutely aware of how much more we need to learn about breast cancer and how urgently we need better therapies. It really gives me hope to be in the lab and to know that I’m working towards something that may make things better for patients.”
Chapel Hill - Patricia Cadle, MRE, BCC, Oncology Chaplain at UNC Health Care’s Department of Pastoral Care, was honored as the 2012 Chaplain of the Year by the North Carolina Chaplains’ Association. This award is presented annually at the Association’s spring conference in recognition of “distinguished ministry in pastoral care” to a chaplain “who serves patients, community and colleagues with grace and innovation.”
CHAPEL HILL, N.C. – Blue Cross and Blue Shield of North Carolina (BCBSNC) has announced Dr. Lisa Carey, Medical Director of the University of North Carolina at Chapel Hill (UNC) Breast Center and Associate Director of UNC Lineberger Comprehensive Cancer Center, as the newest member of its board of trustees.
Chapel Hill, NC – Multiple research projects – including a 2006 study conducted at the University of North Carolina at Chapel Hill – have used DNA microarray analysis to identify several breast cancer subtypes, including luminal A, luminal B, basal-like and HER2-enriched. Simple tests are being developed to help doctors identify these subtypes and to treat their patients in a more biologically-based way. In turn, these tests have made several studies possible that indicate that basal-like, or triple negative breast cancer, is more prevalent in African Americans than their Caucasian counterparts.
Chapel Hill, NC – Does hepatitis C cause liver cancer due to inflammation associated with the disease, or does the virus interact with host cells in a different way to promote the development of cancer?
Victoria Bae-Jump, MD, PhD will serve a two-year term as a junior investigator on the Gynecologic Cancer Steering Committee of the National Cancer Institute, a member institute of the National Institutes of Health.
In the processes of treating most cancers, one of the key pieces of information is the appearance of the tumor under the microscope using a technique called light microscopy. In lung cancer, for example, the appearance of the tumor determines both which chemotherapies are safe and which chemotherapies are effective. In addition, tumor appearance also suggests which patients should be tested for mutations that can be targeted by some of the most effective and safest drugs on the market.
Chapel Hill, NC – Norman E. “Ned” Sharpless, MD, professor of medicine and genetics and Associate Director for Translational Research at UNC Lineberger Comprehensive Cancer Center has been appointed the Wellcome Distinguished Professor in Cancer Research. The professorship was established by the School of Medicine in 1988 with gifts from the Burroughs Wellcome Fund and the William A. Smith Trust of Wadesboro, NC. The gifts were supplemented by the state of North Carolina the Distinguished Professors Endowment Trust Fund to create the endowed professorship.
The finding presents a possible explanation for why so many cancers possess not just genomic instability, but also more or less than the usual 46 DNA-containing chromosomes.
Chapel Hill, NC – Susan G. Komen for the Cure® has awarded a grant of almost $900,000 to Lisa A. Carey, MD, and Gary Johnson, PhD, to research clinical applications for the first broad-based test for protein kinase activation and response to inhibitory drugs in HER2-positive breast cancer.
Chapel Hill, NC – Multiple myeloma is a form of cancer where the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anemia, infection and kidney failure. A medical procedure called autologous hematopoietic stem cell transplantation, commonly known as a stem cell transplant, is frequently an important treatment option for many patients.
Chapel Hill - Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient’s individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient’s response to therapy.
Chapel Hill, NC –A medical procedure called allogeneic hematopoietic cell transplantation, commonly known as a bone marrow or stem cell transplant, is the only known curative option for many patients with life-threatening blood-borne cancers such as leukemia and lymphoma.
Jason Lieb likes to mix it up. A triathlete, he enjoys running, swimming and cycling. In his lab, he works in several model systems: yeast, round worms (C. elegans), fruit flies (Drosophila melanogaster) and human cell lines.
Idoia Garcia, PhD, a postdoctoral fellow in the lab of Timothy Gershon, MD, PhD, has been awarded a Department of Defense Visionary Postdoctoral Fellowship Award. The peer-reviewed award is intended to support exceptionally talented recent medical or other doctoral graduates in their pursuit of cutting-edge, innovative, high-risk/high-impact cancer research during their postdoctoral fellowship.
Channing Der, PhD, Sarah Graham Kenan Professor of Pharmacology, received a two-year $200,000 American Association for Cancer Research Innovative grant from the Pancreatic Cancer Action Network. His grant will fund research on the mechanism of ERK inhibition resistance and ERK-dependent pancreatic cancer.
American and Spanish researchers report potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests.
Which treatment for prostate cancer is most effective? Will a specific combination of cancer drugs increase patient survival for colon cancer? As the pace of scientific discovery continues to accelerate, patients and their providers face more choices and decisions about how to address their health care needs, and information that can help inform their decisions is often hard to find.
Embryonic stem cells are primed to kill themselves if damage to their DNA makes them a threat to the developing embryo. UNC researchers reveal how they do it.
Dr. Joseph DeSimone, PhD, Chancellor's Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill, has been elected into the National Academy of Sciences, one of the highest honors that a U.S. scientist or engineer can receive.
Matthew Milowsky, MD, was recently quoted in the online journal Health News Digest on new therapies for bladder cancer.
Joseph S. Pagano, MD, has been awarded the fifth annual Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research. Dr. Pagano is the director emeritus of UNC Lineberger Comprehensive Cancer Center.
Current nanomedicine research has focused on the delivery of established and novel therapeutics. But a UNC team is taking a different approach.
UNC Lineberger’s 36th annual scientific symposium drew large crowds, with over 450 participants.
UNC’s Seth Noar examines intersection of technology and health
Paul Armistead, MD, PhD, has received a grant of more than $396,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study leukemia stem cell-associated minor histocompatibility antigens.
UNC junior Molly DeCristo attended her first international scientific meeting, but not just as a participant. The American Association for Cancer Research (AACR) honored her poster with a rosette, judging it as “highly rated,” among the top 2.5 percent of those submitted.
A Wayne County woman doesn’t let cancer, its treatment or its recurrence get in the way of her plans to attend her oldest granddaughter’s high school graduation or her own 45th high school reunion.
Chapel Hill - A treatment for localized prostate cancer known as Intensity Modulated Radiation Therapy (IMRT) is better than conventional conformal radiation therapy (CRT) for reducing certain side effects and preventing cancer recurrence, according to a study published in the April 18, 2012 issue of the Journal of the American Medical Association. In 2012, approximately 241,740 American men will be diagnosed with prostate cancer.
CHAPEL HILL, N.C. - As the number of breast cancer survivors increases, now estimated at 2.8 million, more will be living with the chronic effects of cancer treatments or with advanced disease.
James Coghill, MD, has received a grant of more than $529,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study a promising target for new therapies to combat graft versus host disease, a serious complication of treatment for many blood cancers.
National Cancer Institute-designated cancer centers should lead the way
Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.
Chapel Hill, NC – In a paper published today in the journal Nature Methods, a team from the University of North Carolina at Chapel Hill demonstrates a simple, cost-effective technique for three-dimensional RNA structure prediction that will help scientists understand the structures, and ultimately the functions, of the RNA molecules that dictate almost every aspect of human cell behavior. When cell behavior goes wrong, diseases – including cancer and metabolic disorders – can be the result.
Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.
UNC Health Care will offer free screenings during Oral, Head and Neck Cancer Awareness Week, on Wednesday, April 25, from 1 - 4 p.m. in the Ear, Nose, & Throat Clinic on the ground floor of the N.C. Neurosciences Hospital.
Chapel Hill, NC – In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases “en masse”, enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies.
Chapel Hill - Anyone who’s tried a weekend home improvement project knows that to do a job right, you’ve got to have the right tools. For cells, these “tools” are proteins encoded by genes.
Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting
Nancy DeMore, MD, and colleagues presented an abstract at the recent Society of Surgical Oncology 65th annual cancer symposium held in Orlando, Florida in March. Dr. DeMore is an associate professor of surgery and a member of UNC Lineberger.
UNC Cancer Care’s neuro-oncology program will recognize Ependymoma Awareness Day on April 19th, as part of the program’s overall efforts to increase public awareness of this rare tumor and the need for clinical studies to improve early diagnosis, standardize treatment and improve the health status of those living with this disease.
UNC-led team offers clinical, research agenda
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in recent articles in The News & Observer and the Scientific American blog.
Chapel Hill - In a clinical trial of an experimental drug to treat thyroid cancer, UNC and six other institutions report the first evidence in this tumor that targeting therapy to an oncogene documented to be present in the patient receiving therapy may be associated with clinical benefit.
UNC Lineberger faculty members Ned Sharpless, MD, and Adam Zanation, MD, were honored for their achievements by Triangle Business Journal as 2012 Health Care Heroes.
David Ollila, MD, and Craig Burkhart, MD, spoke about teenage tanning bed use at a Child Fatality Task Force committee meeting on March 26, 2012. They discussed the option of banning teenagers below the age of 18 from tanning bed use.
The Lustgarten Foundation, the nation’s largest foundation dedicated solely to funding pancreatic cancer research, has awarded Channing Der, PhD, a $1.165 million grant to identify promising drug combinations for potential future use in clinical trials.
John Baron, MD, was interviewed by Charles Bankhead of MedPage Today on March 21, 2012 to give his perspective on three recently published reviews in "The Lancet" and "The Lancet Oncology." The reviews suggest that "regular aspirin use leads to significant reductions in the risk of cancer, metastasis, and cancer mortality."
A team of scientists, including several from UNC Lineberger, has identified predictive genetic biomarkers in pre-clinical models that affect response to therapy for non-small cell lung cancer (NSCLC). The study was done in parallel to an ongoing clinical trial among lung cancer patients at multiple institutions.
Jared Weiss, MD, gave a podcast titled "2011 Highlights in Lung Cancer" that was posted on cancergrace.org on March 15, 2012. In the podcast, Dr. Weiss talks about highlights in lung cancer from 2011 and also answers questions.
Internationally renowned virologist; past president of national cancer and international virology associations; National Academy of Science Institute of Medicine member; North Carolina Award for Science winner; revered mentor to faculty, fellows, medical and graduate students; Berryhill Lecturer; proud grandfather; dedicated squash and tennis player; and recent honoree at his eightieth birthday.
N.E.D. is a rock band. The members of the band are gynecologic cancer surgeons from all over the country and two of them, Dr. John Boggess and Dr. John Soper, work here at UNC Health Care.
Drs. Christine E. Kistler and Adam Goldstein discuss how clinicians can better have conversations about the balance between short-term risk of adverse cardiovascular events associated with taking Chantix compared to the long-term reduction in the risk of death that results from smoking cessation.
Enduring subtle, insidious acts of racial discrimination is enough to depress anyone, but African-American men who believe that they should respond to stress with stoicism and emotional control experience more depression symptoms, according to new findings from the University of North Carolina at Chapel Hill.
A study of cervical cancer incidence and mortality in North Carolina has revealed areas where rates are unusually high.
The Center for Integrative Chemical Biology and Drug Discovery at the University of North Carolina at Chapel Hill has received a contract from SAIC-Frederick, Inc. to develop potential drug leads for treating renal cell carcinoma, the most common type of kidney cancer in adults.
Small DNA circles found outside the chromosomes in mammalian cells and tissues, including human cells
CHAPEL HILL, N.C. – Researchers from the University of North Carolina at Chapel Hill have helped identify a new DNA entity in mammalian cells and provided evidence that their generation leaves behind deletions in different locations of the cells’ genetic program, or genome.
Tobacco companies have enlisted convenience stores as their most important partners in marketing tobacco products and fighting policies that reduce tobacco use, according to a report released today by leading public health organizations, including The University of North Carolina Gillings School of Global Public Health.
Timothy Gershon, MD, PhD, assistant professor of neurology, has received a four-year National Institutes of Health Mentored Clinical Scientist Research Career Development Award grant from the National Institute of Neurologic Disease and Stroke.
CHAPEL HILL -- A team of researchers at the University of North Carolina at Chapel Hill have successfully flushed latent HIV infection from hiding, with a drug used to treat certain types of lymphoma.
This award, initiated by the AUA Residents Committee and approved by the AUA Board, is presented annually to recognize an outstanding urology educator or program director who has dedicated a portion of his/her career to teaching residents and advancing urology graduate medical education.
Loretta Muss, Coordinator of the N.C. Cancer Hospital Patient and Family Advisory Board, and fellow board member, Ryan Keith, talked about cancer care & families on the February 25, 26, and 27 broadcasts of YOUR HEALTH®.
Chapel Hill, NC – In a paper published today in the journal, Cell, a team from the University of North Carolina at Chapel Hill has explained for the first time how a long-studied protein complex affects cell migration and how external cues affect cell’s ability to migrate.
UNC Lineberger patient David Alston talks about the treatment he is undergoing for testicular cancer.
The story "Shortages Of Life-Saving Drugs Getting Worse" aired today on WFAE 90.7, Charlotte's NPR news source.
The story "Men find emotional support on hospital bathroom's dry erase board" aired on February 23, 2012 on WRAL.
UNC Lineberger’s Carolina Well and the Comprehensive Cancer Support Program (CCSP) offered a workshop on “Cancer Transitions: Promoting Wellness & Group Process” for community outreach coordinators and their community partners as well for interested UNC nurses and staff.
Chapel Hill, NC – A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross – a “library” of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.
Training the next generation of scientists is vital to continued progress in understanding cancer and all human disease. But how do students evaluate the programs offered by colleges and universities to decide which program is the best fit for them?
Making a simple substitution of water or diet soft drinks for drinks with calories can help people lose four to five pounds, a new University of North Carolina at Chapel Hill study shows.
Super Bowl Sunday was super for another reason.
A new online resource is available to help connect women and adolescents to life-saving cervical cancer-related services.
Scientists from UNC Lineberger have published a report describing an outreach program they developed for breast cancer survivors in four NC counties.
First cases in Triangle done at UNC
Lawrence Marks, MD, chair of UNC's department of radiation oncology and a UNC Lineberger member, is quoted in the article "TomoTherapy offers safer radiation" published in today's issue of The News & Observer.
Becker's Hospital Review has named the N.C Cancer Hospital as one of "70 Hospitals with Great Oncology Programs."
Bladder cancer patients in the Triangle area are not alone. They have a monthly group where “true loving support for each other” is shared, says David Langham, a bladder cancer survivor and one of the organizers of the group.
UNC and partners to study policies to restrict tobacco marketing at point of sale: multi-institutional $6.7 million research grant awarded
The way tobacco products are marketed and sold changed with the June 2009 passage of the Family Smoking Prevention and Tobacco Control Act. For example, this law mandates larger and stronger warning labels on packs and advertising and prohibits the sale of “light” and clove cigarettes. The FDA Act also now allows states and local communities to regulate the time, place, and manner of tobacco advertising. Thus, states could restrict tobacco promotions or restrict the location of tobacco advertising.
In 2008 UNC and Harvard University’s Brigham and Women’s Hospital in Boston were selected by the U.S. Agency for Healthcare Research and Quality to carry out accelerated practical studies examining the comparative effectiveness of cancer treatments. The collaboration is called the Cancer Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Comparative Effectiveness Consortium.
As part of Patient Power® coverage of the annual meeting of the American Society of Hematology (ASH), UNC Lineberger member Steven Park, MD, talks about the latest in treatment for Hodgkin Lymphoma.
When Chase Jones organized Basebald for the Cure, he hit a home run!
Whether photographing a child in the streets of Vietnam or consulting with a patient about a diagnosis, Dr. Paul Godley employs his intuition and charming personality to put the person in front of him at ease within a matter of moments.
Coca-Cola and Tar Heel Athletics team up to help cancer research and treatment.
UNC scientists collaborate to find first major genetic mutation associated with hereditary prostate cancer risk
Chapel Hill - After a 20-year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the disease.
UNC radiation oncologists co-author Journal of Clinical Oncology editorial on breast cancer radiotherapy and coronary artery stenosis
Timothy Zagar, MD, assistant professor of radiation oncology, and Lawrence Marks, MD, professor and chair of radiation oncology, co-authored an editorial in the December 27, 2011 issue of the Journal of Clinical Oncology.
Chapel Hill, NC - How much medical information does a woman understand and retain about her breast cancer diagnosis? UNC scientists participated in a four-institution study involving 440 women with early-stage breast cancer and found that breast cancer survivors had limited knowledge about their surgical options, including an understanding of something as important as the risk of recurrence.
Benjamin E. Haithcock, MD, an assistant professor in UNC's Division of Cardiothoracic Surgery and a member of UNC Lineberger, discussed esophageal cancer in an interview that was aired on the January 5, 2012 segment of the radio show "Make it Happen."
Deborah Tate, PhD, associate professor in the Department of Health Behavior and Health Education and the Department of Nutrition at UNC-Chapel Hill, is quoted in the article "Latest gadgets give diets, workouts a high-tech boost" published in today's issue of The News & Observer.
UNC Lineberger geriatric oncology program leaders co-author Journal of Clinical Oncology editorial about older women and breast cancer
UNC Lineberger Geriatric Oncology program leaders Hy Muss, MD, and Jan Busby-Whitehead, MD, co-authored an editorial in the December 10, 2011 issue of the Journal of Clinical Oncology. Muss is professor of medicine. Busby-Whitehead is professor of medicine, and director of the UNC School of Medicine’s Center for Aging and Health and Division of Geriatric Medicine.
UNC Lineberger GI Oncology program directors Joel Tepper, MD, and Bert O’Neil, MD, co-authored an editorial in the December 10, 2011 issue of the Journal of Clinical Oncology. Tepper is the Hector McLean Distinguished Professor of Cancer Research. O’Neil is associate professor of medicine.
New research study examines behavioral economics of colorectal cancer screening in underserved populations
CHAPEL HILL, N.C. – A new study at UNC Chapel Hill will examine what complex and conjoined behavioral factors influence low income people to pursue colorectal cancer screening and what strategies could increase screening rates in disadvantaged communities.
Nancy E. Thomas, MD, PhD, was appointed the first Irene and Robert Alan Briggaman Distinguished Professor. The professorship is named in honor of Dr. Briggaman, who served as chair of the UNC Department of Dermatology from 1987-1999, and his wife, Irene.
Mechanism explains how virus survives in the liver and how a new antiviral works
Ruben Gonzalez-Crespo, a Spanish interpreter at UNC Lineberger Comprehensive Cancer Center, was highlighted in the November 2011 issue of the University Gazette in an article titled "Former singer finds new voice helping others battle cancer."
The Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO) will award 20 oncology trainees with Merit Awards at the 2012 Genitourinary Cancers Symposium. The symposium will be held February 2 - 4, 2012 in San Francisco.
Tori Frahm has experienced just eight Christmases, but she epitomizes the true spirit of the holiday. She and her family organized collection and delivery of 750 presents for pediatric oncology patients and their siblings at UNC Lineberger Comprehensive Cancer Center. The gifts helped 125 families have a brighter holiday.
One neighborhood in Cary has become the centerpiece of a holiday tradition that benefits UNC Lineberger.
Chapel Hill, NC – In an editorial published today in the Journal of Clinical Oncology, UNC associate professor E. Claire Dees, MD, reviews current evidence on the safety and efficacy of combination therapies currently used for metastatic breast cancer and urges clinical researchers to move forward with new studies that leverage advances in the identification of tumor biomarkers.
Six University of North Carolina at Chapel Hill faculty members have been named fellows of the American Association for the Advancement of Science.
Dr. Marci Campbell, professor of nutrition at the University of North Carolina Gillings School of Global Public Health, died December 14 after living with cancer with grace and caring for almost two years.
Weili Lin, PhD, has been elected a Fellow of the American Institute for Medical and Biological Engineering. Lin was cited for his outstanding contributions to the development and translation of MR functional neuroimaging.
American Cancer Society Revises Cancer Screening Guideline Process; UNC scientists are report co-authors
ATLANTA –December 13, 2011– The American Cancer Society has revised its guideline formation process to achieve greater transparency, consistency, and rigor in creating guidance about cancer screening. The new methods align with new principles from the Institutes of Medicine (IOM) by creating a single generalist group for writing the guidelines, commissioning systematic evidence reviews, and clearly articulating the benefits, limitations, and harms associated with cancer screening tests. The new process is outlined in a Special Communication in the December 14, 2011 issue of the Journal of the American Medical Association.
CHAPEL HILL – The era of widely available next generation personal genomic testing has arrived and with it the ability to quickly and relatively affordably learn the sequence of your entire genome. This would include what is referred to as the “exome,” your complete set of protein-coding sequences.
Chapel Hill - The complete sequence of an individual’s genome – all 3 billion DNA building blocks - will soon be affordably available to doctors, patients and even consumers. While knowledge of one’s genome may have important medical benefits, tremendous questions remain regarding an avalanche of such data means and how they should be used. Many clinical, ethical and social issues arise from the evaluation, use and sharing of the data.
Donald Rosenstein, MD, professor of psychiatry and medicine in the UNC School of Medicine and director of the UNC Comprehensive Cancer Support Program, will serve a one-year term as president of the Academy of Psychosomatic Medicine. Dr. Rosenstein is a member of UNC Lineberger Comprehensive Cancer Center.
President Obama has announced his intent to nominate Barbara K. Rimer, DrPH, Dean and Alumni Distinguished Professor of the University of North Carolina Gillings School of Global Public Health, to chair the President’s Cancer Panel. The panel was established as part of the National Cancer Act, signed by President Nixon in 1971
The molecule is the protein Shc (pronounced SHIK), and new blood vessel formation, or angiogenesis, is seriously impaired without it.
UNC scientists contribute cell studies and protein expression analysis
Blossom Damania, PhD, was a speaker at the Twenty-third Annual Kavli Frontiers of Science Symposium, held November 17-19, 2011 in Irvine, California. The symposium is hosted by the National Academy of Sciences.