Nigel S Key

Nigel S Key, MB, ChB, FRCP, is a UNC Lineberger Comprehensive Cancer Center member, Director of the Hemophilia and Thrombosis Center and Harold R. Roberts Professor of Medicine in the Division of Hematology and Oncology at UNC-Chapel Hill.

Nigel S Key

UNC-Chapel Hill
Clinical Research

Lab Website

Area of interest

My clinical and laboratory interest is in thrombosis and hemostasis.  My laboratory has been focused on understanding the role of circulating tissue factor - the 'trigger' for coagulation - in the pathogenesis of disorders of hemostasis and thrombosis. Better assays and clinical studies are needed in this area to ultimately determine whether the tissue factor pathway may be exploited in the treatment of bleeding disorders or as a target for anti-thrombotic agents. Disease areas of focus have been cancer-associated thrombosis, sickle cell disease, and human experimental endotoxemia.

I also direct the T32 Training grant in hematology at UNC, which includes MD and PhD training slots in benign hematology.

Awards and Honors

  • 1976 Harkness Bursary, University of St. Andrew's
  • 1991 Watson Award, University of Minnesota Medical School
  • 1999 Individual NRSA, NIH
  • 1995-2000 NIH FIRST Award
  • 1998 Teacher Of The Year Award, Dept of Medicine, University of Minnesota Medical School
  • 1999 Elected Fellow, Royal College of Physicians (London)
    2000 Outstanding Care Provider Award, Hemophilia Foundation of MN and Dakota
  • 2002-2006 Best Doctors in America
  • 2003 12th Annual Clinical Scholar Award, University of Minnesota Physicians
  • 2003 Researcher of the Year Award, National Hemophilia Foundation
  • 2004 Editorial Advisory Board, Journal of Thrombosis and Haemostasis
  • 2005 Associate Editor, Thrombosis Research
  • 2005 American Clinical and Climatological Association
  • 2005 Harold R. Roberts Distinguished Professor, UNC
  • 2005 Best Doctors, Minneapolis-St Paul Magazine
  • 2014-16 Chair of Council, International Society on Thrombosis and Haemostasis
  • 2015 Biggs-MacFarlane Plenary Lecture, British Society of Haematology

Link to Publications on Reach NC site

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