PCCE News Archives - UNC Lineberger

A phase I gene therapy study at UNC Lineberger is now recruiting patients with refractory pancreatic ductal adenocarcinoma (PDAC) to test the safety and tolerability of escalating doses of iC9.CAR.B7-H3 T-cells.

Headshots of Channing Der and Adrienne Cox.

NIH Director Monica Bertagnolli, MD, wrote about research led by UNC Lineberger’s Channing Der, PhD, and Adrienne Cox, PhD, that provided the most comprehensive molecular portrait of the workings of KRAS.

Jen Jen Yeh speaks at a podium at the 2024 UNC Lineberger Scientific Symposium.

UNC Lineberger’s 47th annual scientific symposium featured 17 presentations from faculty at UNC Lineberger and institutions across the United States.

UNC Lineberger researchers have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene, and how its activities impact pancreatic cancer outcomes.

The grant will support the first metastatic pancreatic cancer trial in the country to evaluate whether selecting treatment by tumor subtype will help patients match to more effective first-line therapies.

Seven arms in a circle with a diverse range of skin tones.

The PROmoting CLinicAl TrIal EngageMent for Pancreatic Cancer App Study (PROCLAIM Study), which is focused on breaking down barriers to diverse clinical trial population recruitment, is enrolling patients.

We have recently been added as a study location for two phase I clinical trials currently recruiting patients with pancreatic ductal adenocarcinoma (PDAC).

Kirsten Bryant, PhD, shares what motivates her in the lab, how mentorship and advocacy have fueled her passion for pancreatic cancer research, and why she's encouraged by progress made in the past decade.

Jen Yeh, MD, has been appointed to the Pancreatic Cancer Action Network’s scientific and medical advisory board, which is comprised of leading scientists, clinicians and healthcare professionals across the United States.

Headshots of Shelley Earp and Yuliya Pylayeva-Gupta

The NCI has awarded has awarded Shelley Earp, MD, and Yuliya Pylayeva-Gupta, PhD, a research project grant to investigate approaches to overcome barriers to pancreatic cancer immunotherapies.

Category: PCCE News

Study testing CAR T therapy in refractory pancreatic cancer opens to accrual

NIH Director’s blog features pancreatic cancer research led by Der and Cox

Scientific symposium highlights latest developments in pancreatic cancer research

Molecular pathway that impacts pancreatic cancer progression and response to treatment detailed

Yeh, Johnson awarded five-year, $3.2 million research grant from NCI

PROCLAIM Study open to accrual

Two pancreatic cancer clinical trials now recruiting at UNC Lineberger

Inspired research: A conversation with Kirsten Bryant, PhD

Pancreatic Cancer Action Network names Yeh to scientific and medical advisory board

NCI awards Earp, Pylayeva-Gupta five-year, $2.69 million pancreatic cancer research grant