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Brian Kuhlman, PhD, is a UNC Lineberger Comprehensive Cancer Center member, Co-Director of UNC Molecular and Cellular Biophysics Program, and Professor of Biochemistry and Biophysics at the UNC-Chapel Hill School of Medicine.

Professor, Biochemistry & Biophysics
Oliver Smithies Investigator
Co-Director, UNC Molecular and Cellular Biophysics Program
UNC-Chapel Hill
Molecular Therapeutics

Area of Interest

The focus of my laboratory is the development and application of computational methods for protein design. We are testing our software on a variety of design problems including the creation of novel protein-protein interactions and protein switches. In several cases, the proteins we are engineering will be useful for studying cancer and potentially treating cancer.

Awards and Honors

  • W.M. Keck Foundation Young Investigator in Medical Sciences, 2005-2010
  • AAAS Newcomb Cleveland Prize, 2004
  • Foresight Institute Feynman Prize in Nanotechnology, 2004
  • Searle Scholar, 2004-2007
  • Beckman Young Investigator, 2004-2007
  • Sloan Research Fellow, 2004
  • Damon Runyon/Walter Winchell Cancer Research Fund Postdoctoral Fellowship, 1999-2002
  • Stony Brook President’s award for excellence in research by a graduate student, 1998
  • Stony Brook President’s award for excellence in teaching by a graduate student, 1995
Headshot of Brian Kuhlman