Douglas H. Phanstiel

Assistant Professor; Thurston Arthritis Research Center
UNC-Chapel Hill
Cancer Genetics

Area of interest

The overarching mission of my lab is to gain a functional and mechanistic understanding of how DNA loops control gene transcription during cellular differentiation. We employ an interdisciplinary approach that combines existing genomic, proteomic, bioinformatic, and genome editing technologies with the development of new experimental and computational tools to interrogate 3D chromatin architecture. Insights gleaned from my lab’s research will have a broad impact on our understanding of chromatin structure, the molecular mechanisms of disease, and gene regulation as a whole.

Awards and Honors