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Gary L Johnson, PhD, is a UNC Lineberger Comprehensive Cancer Center member and Kenan Distinguished Professor and Chair in the Department of Pharmacology at UNC-Chapel Hill. Johnson Lab studies the primary signal relay systems and how they regulate gene expression, cell growth, development and apoptosis.

Professor and Chair, Department of Pharmacology
Co-Leader, UNC Lineberger Molecular Therapeutics Research Program
UNC-Chapel Hill
Molecular Therapeutics

Area of Interest

As a translational basic scientist, my research interests focus on understanding the behavior of the kinome en masse in cancer. My laboratory has developed chemical proteomics methods that allows measurement of the functional state of ~90% of the kinome that can be applied to cell lines, preclinical animal models, patient-derived xenografts and clinical trials. My laboratory integrates kinome proteomics with next generation sequencing and chromatin epigenetics to define the dynamic behavior and function of the kinome at both baseline and with perturbation. Our focus is on defining mechanisms of resistance to targeted kinase inhibitors.

Find publications on PubMed

Awards and Honors

  • Battle Award for Cancer Research, UNC-Chapel Hill

News and Stories

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