Gary L. Johnson

Gary L Johnson, PhD, is a UNC Lineberger Comprehensive Cancer Center member and Kenan Distinguished Professor and Chair in the Department of Pharmacology at UNC-Chapel Hill. Johnson Lab studies the primary signal relay systems and how they regulate gene expression, cell growth, development and apoptosis.

PhD
Professor and Chair, Department of Pharmacology
UNC-Chapel Hill
Molecular Therapeutics
Breast Cancer

Area of interest

As a translational basic scientist, my research interests focus on understanding the behavior of the kinome en masse in cancer. My laboratory has developed chemical proteomics methods that allows measurement of the functional state of ~90% of the kinome that can be applied to cell lines, preclinical animal models, patient-derived xenografts and clinical trials. My laboratory integrates kinome proteomics with next generation sequencing and chromatin epigenetics to define the dynamic behavior and function of the kinome at both baseline and with perturbation. Our focus is on defining mechanisms of resistance to targeted kinase inhibitors.

Awards and Honors

  • Battle Award for Cancer Research

Link to Publications on Reach NC site

Find Publications on PubMed

  • Phone Number

    (919) 619-5091 (Office Phone)

  • Address

    4016 Genetic Medicine Building Chapel Hill

    CB #7365

    Chapel Hill, NC 27599-7305