Associate Professor, Medicine-Oncology
Associate Director for Finance, UNC Lineberger Clinical Protocol Office
Thoracic Oncology Program
Meet Jared Weiss
Area of Interest
My primary focus is on personalized immunotherapy for lung cancer and for head/neck cancer. At the current time, my primary effort is PANDA-VAC, a personalized and adaptive vaccine generated from prediction of Neo-antigens (LCCC1804). I am also in the early stages of cellular therapeutics work targeting GD2 and MAGE-A4 and in very early work on a novel mechanism for better selection of TIL (tumor infiltrating lymphocytes) products.
I am the national PI for investigator-initiated trials evaluating the introduction of oncolytic virus into malignant pleural effusions (LCCC1626), induction chemo-immunotherapy in locally advanced, surgically resectable head and neck cancer (LCCC1621), and adjuvant immune-radiotherapy in head/neck cancer (LCCC1725). A funded effort to evaluate LXR/ApoE agonism to reduce MDSCs (LCCC1925) is funded and in the protocol writing stage.
I also lead and participate in several international industry efforts; key amongst these is ILIAD (IM-202, ilixadencel dendritic cell infusion into solid tumors). Other efforts include immunolight, LOXO-292 (RET inhibitor) and trilacyclib (CDK4/6 inhibitor for myelopreservation in SCLC, manuscript under minor revisions at Annals of Oncology).
Awards and Honors
- Jimmy V Foundation Translational/Clinical Award, 2018-2020
- UNC Seq V2 award, 2018-2021
News and Stories
UNC Lineberger recognizes Lung Cancer Awareness Month in November
UNC Lineberger faculty and staff have been holding events throughout November to educate the community on the latest research and clinical advances in lung cancer.
UNC football player diagnosed with rare lung cancer shares story with ESPN
Tylee Craft, a junior wide receiver, sat down with ESPN to share an update on his cancer journey and when he hopes to get back on the field to play.
UNC Lineberger faculty present research at the American Society of Clinical Oncology annual meeting
UNC Lineberger members will be presenting research findings, providing commentary and leading education sessions at the American Society of Clinical Oncology’s 58th annual meeting.
Loved ones battling cancer inspire donor’s gift
After seeing friends and family members struggle with cancer and tired of feeling helpless, Betsy Jordan decided to do something about it by making a gift to support innovative research.