MD
Professor of Surgery and Pharmacology; Oliver Smithies Investigator
Co-Leader, UNC Lineberger Clinical Research Program
Director, UNC Lineberger Pancreatic Cancer Center of Excellence
Vice Chair for Research, Department of Surgery
UNC-Chapel Hill
Clinical Research
Gastrointestinal Oncology Program, UNC Lineberger Pancreatic Cancer Center of Excellence
Area of Interest
Jen Jen Yeh, MD, maintains an active clinical practice taking care of patients with endocrine (thyroid, parathyroid and adrenal) diseases and pancreatic cancer. Her research focus centers on the use of genomics to identify new approaches for pancreatic cancer.
Yeh received her medical degree from Johns Hopkins University and completed her general surgery residency at the Boston Medical Center, a research fellowship at Dana-Farber Cancer Institute, and a surgical oncology fellowship at the Memorial-Sloan Kettering Cancer Center.
In 2015, Yeh identified new molecular subtypes of pancreatic cancer that have may have biological and clinical significance. To translate molecular subtypes to the clinic, her group developed a single sample classifier that is now being developed for clinical use. Yeh and her collaborators also have developed a device that could help drive chemotherapy drugs directly into pancreatic tumor tissue to prevent their growth and shrink them. Yeh co-founded Advanced Chemotherapeutic Technologies, Inc. in order to bring the device into clinical trials. Yeh’s group is focused on identifying vulnerabilities in tumors to guide treatment for patients.
Awards and Honors
- Hyman L. Battle Distinguished Cancer Research Award, UNC-Chapel Hill, 2023
News and Stories
Serody and Yeh honored with Battle Distinguished Cancer Research Award
Jonathan Serody, MD, and Jen Jen Yeh, MD, were named the 2023 recipients of the Hyman L. Battle Distinguished Cancer Research Award, recognizing their significant scientific achievements.
Rashid awarded grant to develop AI tool that recommends optimal clinical trials to pancreatic cancer patients
Naim Rashid, PhD, has received a Department of Defense Pancreatic Cancer Research Program pilot award to build an AI tool that generates personalized clinical trial recommendations for patients with PDAC.
