MD
Professor of Surgery and Pharmacology; Oliver Smithies Investigator
Co-Leader, UNC Lineberger Clinical Research Program
Director, UNC Lineberger Pancreatic Cancer Center of Excellence
Vice Chair for Research, Department of Surgery
Assistant Dean for Translational Research, UNC School of Medicine Office of Research
UNC-Chapel Hill
Clinical Research
Gastrointestinal Oncology Program, UNC Lineberger Pancreatic Cancer Center of Excellence
Area of Interest
Jen Jen Yeh, MD, maintains an active clinical practice taking care of patients with endocrine (thyroid, parathyroid and adrenal) diseases and pancreatic cancer. Her research focus centers on the use of genomics to identify new approaches for pancreatic cancer.
Yeh received her medical degree from Johns Hopkins University and completed her general surgery residency at the Boston Medical Center, a research fellowship at Dana-Farber Cancer Institute, and a surgical oncology fellowship at the Memorial-Sloan Kettering Cancer Center.
In 2015, Yeh identified new molecular subtypes of pancreatic cancer that have may have biological and clinical significance. To translate molecular subtypes to the clinic, her group developed a single sample classifier that is now being developed for clinical use. Yeh and her collaborators also have developed a device that could help drive chemotherapy drugs directly into pancreatic tumor tissue to prevent their growth and shrink them. Yeh co-founded Advanced Chemotherapeutic Technologies, Inc. in order to bring the device into clinical trials. Yeh’s group is focused on identifying vulnerabilities in tumors to guide treatment for patients.
Awards and Honors
- Hyman L. Battle Distinguished Cancer Research Award, UNC-Chapel Hill, 2023
News and Stories
UNC Lineberger and UNC faculty and trainees present findings at AACR annual meeting
Nearly 30 UNC Lineberger and UNC faculty and trainees will present findings and participate during the American Association for Cancer Research annual meeting in Chicago, April 25-30.
UNC Lineberger hosts NCI in gastrointestinal cancer SPORE Investigators Meeting
The nation’s top gastrointestinal cancer clinical translational researchers convened in Chapel Hill for the 2025 GI SPORE Investigators Meeting.
