Assistant Professor, Pharmacotherapy and Experimental Therapeutics
UNC Eshelman School of Pharmacy
Area of Interest
The research interests of Klarissa Jackson, PhD, focus on drug metabolism and toxicology to better understand the mechanisms and risk factors of adverse drug reactions and improve drug safety.
Jackson’s research program has been supported by funding from the NIH National Cancer Institute Center to Reduce Cancer Health Disparities, the National Institute of General Medical Sciences, and the American Association of Colleges of Pharmacy. Her laboratory is currently investigating the role of cytochromes P450 in the metabolism and hepatotoxicity of tyrosine kinase inhibitors used in targeted cancer therapy. She is interested in understanding the impact of variability in drug metabolism and disposition on individual risk for drug toxicity. The long-term goal of this research is to better predict and prevent serious adverse reactions and improve drug safety in diverse patient populations.